EUVIMEDEuropean Health Evidence
Uhr 10/10Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Therapie & Reha · Seite 113

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
19.08.2026journal-article

Musculoskeletal Care

Rehabilitation Experiences and Support Needs of Patients With Hemiplegic Shoulder Pain Based on the ICF Framework: A Qualitative Study

Xingyu Li, Hualu Yang, Minghong Sui, Jiaqing Liu, Xin Wang, Xiaotian Liu, Guangfa Xiang, Rui Luo, Yanhong Chen, Beirong Mo

ABSTRACT Background Hemiplegic shoulder pain (HSP) multi‐dimensionally affects the rehabilitation process of stroke survivors. Although previous literature has explored post‐stroke functional recovery, empirical qualitative investigations into the authentic rehabilitation experiences and deep care needs of this specific population during hospitalisation remain to be further elucidated. Objective Guided by the International Classification of Functioning, Disability and Health (ICF) framework, this study aimed to exp …

19.08.2026journal-article

Frontiers in Endocrinology

Elevated IGF-1 levels are associated with accelerated bone age advancement during growth hormone therapy in children: a multicenter cohort study

Jungmin Ahn, Hwalrim Jeong, Junghwan Suh, Hyun Wook Chae

Background Elevated insulin-like growth factor-1 (IGF-1) levels are associated with earlier pubertal onset and accelerated bone maturation. However, the effect of IGF-1 increases during growth hormone (GH) therapy on bone age (BA) advancement across different etiologies of short stature remains unclear. Methods This multicenter observational study included 1,944 children with idiopathic growth hormone deficiency (IGHD), idiopathic short stature (ISS), or small for gestational age (SGA) enrolled in the LG Growth Stu …

19.08.2026journal-article

Borderline Personality Disorder and Emotion Dysregulation

Understanding stakeholder views on dialectical behavior therapy for post-traumatic stress disorder: a qualitative analysis of clinician and patient experiences

Laurie Nadeau, Émiliane Larrivée, Anne-Sophie Paré, Christine Therriault, Alain Taillefer, Florence Charest, Alexandre Hudon, Félix-Antoine Bérubé, Lionel Cailhol

Abstract Background Individuals with Borderline Personality Disorder (BPD) and Complex Post-Traumatic Stress Disorder (C-PTSD) often face significant challenges in treatment due to the severity and complexity of their symptoms. Dialectical Behavior Therapy for PTSD (DBT-PTSD) is a phase-based, multicomponent psychotherapy developed to address the needs of this population. While its efficacy has been demonstrated in clinical trials, little is known about how patients and clinicians experience this treatment. Methods …

19.08.2026journal-article

American Journal for Young Scientists

Artificial Intelligence for Early Detection of Alzheimer's Disease: A Comparative Review of Speech, Neuroimaging, and EEG Biomarkers

Hudson Barber

Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common cause of dementia globally. Accurate and early diagnosis of AD is essential to enhance patient care and management, facilitate recruitment for clinical trials, and provide access to novel treatments at a stage when intervention may have greater potential benefit. However, the early detection of AD before obvious clinical symptoms have emerged is challenging. Firstly, there is no unique, widely available screening test for early dia …

19.08.2026journal-article

Cancers

B Cell Aplasia Following CAR T Cell Therapy: Incidence, Kinetics, Prognostic Implications, and Clinical Management

Malak Khalifeh, Malini Surapaneni, Huda Salman

B cell aplasia (BCA), the sustained depletion of circulating CD19-positive B cells, is the defining on-target, off-tumor consequence of anti-CD19 chimeric antigen receptor (CAR) T cell therapy. Despite its occurrence across all approved CAR T cell products and all responding patients, BCA has not been systematically reviewed as a standalone clinical and biological phenomenon. This review synthesizes data from landmark trials and real-world cohorts across B cell-acute lymphoblastic leukemia (B-ALL), large B cell lym …

19.08.2026journal-article

Radiation Protection Dosimetry

Occupational effective doses for regional and university hospitals in Albania (2021–2025): optimization and statistical analysis

Ervis Gega, Elida Bylyku, Elda Spahiu, Brunilda Daci, Klaudia Kaçori

Abstract The Institute of Applied Nuclear Physics conducts periodic monitoring of doses for occupationally exposed workers in Albania. This is the first study in Albania that includes all regional and university hospitals in the country. Measurements are carried out in 2-month periods using thermoluminescent dosemeters composed of LiF:Mg,Ti crystals which are measured with the Harshaw 6600 and Harshaw 4500 reader. The results indicate that the average dose for the years 2021 to 2025 is 0.62 mSv y−1 and collective a …

19.08.2026journal-article

International Journal of Veterinary Medicine

Rationale for the use of testicular hyaluronidase in the therapy of bovine mastitis

S. V. Nikolaev, A. A. Zalevskiy

The study evaluated the effectiveness of testicular hyaluronidase in the treatment of mastitis in cows. The research was conducted on Holstein animals with recurrent catarrhal inflammation of one udder quarter (more than twice per lactation). All animals (n=20) underwent therapy, which included a supramammary novocaine block and an injection of an anti-inflammatory agent on the first day of treatment, as well as intracisternal administration of the drug «Mastiet Forte» until clinical recovery. The experimental grou …

19.08.2026journal-article

Advanced Materials

Machine Learning‐Based Screening of Optimal miRNA Targets Enabled by a Cytosolic Delivery Carrier for Augmenting Cancer Therapy

Hang Xu, Pengxiang Min, Yanbin Fu, Ge Sun, Hui Wu, Mengqiao Pan, Chaoxian Zhao, Jiatong Li, Ying Wu, Ying Xu, Bin Gu, Jiahua Pan, Lin Zhang, Peifeng Liu

ABSTRACT Nucleic acid therapeutics offer promise for precision cancer treatment, but are limited by inaccurate target selection and inefficient delivery. This work presents a therapeutic platform combining dual machine learning models (LASSO and RSF)‐based miRNA target screening with a modular biomimetic nanocarrier system. Systematic screening and experimental validation identify miR‐873 as a previously uncharacterized tumor‐suppressive miRNA in prostate cancer, and miR‐20a as oncogenic. Mechanistic studies reveal …

19.08.2026journal-article

Antibiotics

Does a Loading Dose Improve Outcomes? Colistin Therapy for Urinary Tract Infections Caused by Multidrug-Resistant Gram-Negative Bacteria

Wasan Katip, Puntapong Taruangsri, Siriporn Okonogi, Shaun Wen Huey Lee, Ajaree Rayanakorn

Background: Colistin remains an important therapeutic option for complicated urinary tract infections (cUTIs) caused by multidrug-resistant Gram-negative bacteria. A loading dose is often recommended to rapidly achieve steady-state plasma concentrations, but its clinical benefit specifically for cUTIs, where local urinary drug concentrations markedly exceed plasma levels, remains unclear. Methods: We conducted a retrospective cohort study of adult patients treated with intravenous colistin for cUTIs at Nakornping H …

19.08.2026journal-article

Journal of Translational Medicine

Epitranscriptomic RNA modifications in cancer DNA damage response: mechanistic links between RNA fate, genome maintenance, and therapy resistance

Xiaoning Yang, Hongxiu Wang, Jiawei He, Shuqiang Yang, Meijia Zhao, Luqian Zhao, Jingjing Wang, Xiaowen Chen, Xin Xu, Hongran Qin

Abstract Epitranscriptomic RNA modifications have emerged as a fundamental regulatory layer linking RNA metabolism with genome maintenance, DNA damage response (DDR), and therapeutic resistance during cancer evolution. Throughout tumorigenesis, persistent oncogenic signaling, replication stress, oxidative stress, metabolic reprogramming, chronic inflammation, and anticancer treatments continuously generate DNA lesions that challenge genome integrity. Although the DDR network normally safeguards genomic stability by …

19.08.2026journal-article

Egyptian Rheumatology and Rehabilitation

Effect of peripheral neuropathy on Achilles tendon: ultrasonographic study

Youssy Saeed Eshak Gergius, Mona Mansour Hassab Elnaby, Alshymaa Mohamed Farouk Mohamed Motaher, Salwa Galal Moussa

Abstract Introduction Type 2 diabetes mellitus (T2DM) is frequently associated with diabetic peripheral neuropathy (DPN) and musculoskeletal complications, including Achilles tendon abnormalities. Limited evidence exists regarding if tendon abnormalities progress with increasing neuropathy severity or not. Therefore this study aimed to compare ultrasonographic Achilles tendon abnormalities between patients with T2DM with and without DPN, to investigate the relationship between neuropathy severity and tendon structu …

19.08.2026journal-article

SEISENSE Journal of Management

The Double-Edged Effects of Hybrid Work on Employee Well-Being

Ryan Basith Fasih Khan

Purpose: This study maps and synthesizes research on hybrid work and employee well-being, explaining its simultaneous resource and demand effects.Design/Methodology: Following PRISMA 2020 and SPAR-4-SLR, 250 Scopus records published from 2020 to 3 June 2026 were screened. After excluding 26 articles in press, 224 articles were bibliometrically mapped and 200 underwent structured title-abstract synthesis using VOSviewer and thematic coding.Findings: Five clusters organize the field. Flexibility and autonomy appeared …

19.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

BEYOND THE BIOMEDICAL MODEL: PHYSICAL THERAPY EXPERT EXAMINATION AS A GUARANTEE OF OBJECTIVITY IN LABOR TECHNICAL EVIDENCE

Rodrigo Moreira Campos, Samantha de Freitas Campos, Andervan Aguiar de Lima

This study analyzes the technical, scientific, legal, and regulatory foundations that support the practice of physical therapists as judicial experts and technical assistants in labor courts. Through a narrative literature review and theoretical-documentary analysis, the study addresses the core role of human functioning evaluation in establishing work capacity, occupational restrictions, and technical evidence. The central problem lies in overcoming the strictly biomedical paradigm in labor litigations, shifting t …

19.08.2026journal-article

Frontiers in Computer Science

Integrating human–computer interaction and real-time thermal imaging: user-centered design of a thermographic system for physical rehabilitation

Margarita Kaplun-Mucharrafille, Alberto Rossa-Sierra, Rita Q. Fuentes-Aguilar, David Vidaña-Zavala

Infrared thermography has emerged as a non-invasive technique for monitoring physiological processes in clinical rehabilitation; however, its adoption remains limited due to challenges in usability, data integration, and measurement reliability. This work presents the design and development of a thermographic medical device with a user-centered graphical user interface (GUI), integrating real-time thermal acquisition, processing, and analysis within a unified clinical workflow. The proposed system is based on a mod …

19.08.2026journal-article

npj Digital Medicine

In silico trials for sex-specific patient inclusion criteria in cardiac resynchronization therapy

Shuang Qian, Devran Ugurlu, Elliot Fairweather, Richard E. Jones, Hassan Zaidi, Sanjay Prasad, Brian P. Halliday, Daniel Hammersley, Gernot Plank, Edward Vigmond, Cristobal Rodero, Abdul Qayyum, Derek Bivona, Kenneth C. Bilchick, Christopher A. Rinaldi, Alistair Young, Pablo Lamata, Martin Bishop, Steven Niederer

Abstract Cardiac resynchronization therapy (CRT) guidelines are based on clinical trials with limited female representation and inconsistent left bundle branch block (LBBB) definitions. Conventional QRS duration (QRSd) criteria show variable diagnostic accuracy between sexes, partly due to differences in heart size and remodelling. We evaluated the influence of sex, heart size, LBBB, and conduction delay on QRSd and assessed the diagnostic performance of conventional and indexed QRSd criteria using a population-bas …

19.08.2026journal-article

Cancer Research Communications

FGFR1 suppresses STING-mediated interferon response in endocrine therapy resistant breast cancer

Torbjørn Amundsen. Lien, Sushil Dhakal, Anne Marthe. Fosdahl Wium, Helga Bergholtz, Serhat Gunesten, Helene Midtun. Flatekvål, Daniel Nebdal, Phuong Vu, Antoni Hurtado, Jens Henrik. Norum, Therese Sorlie

Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification is frequently observed in ER⁺/HER2⁻ breast cancer and has been linked to poor response to endocrine therapy. While FGFR1 has been implicated in therapeutic resistance, its role in regulating interferon (IFN) response in the context of endocrine resistance remains unclear. We investigated whether FGFR1 modulates the IFN response through the GMP-AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway in tamoxifen-resistant breast cancer. We …

19.08.2026journal-article

Occupational Health

Mental Health Disclosure and Employability Perceptions: An Evaluation of Trustworthiness, Job Suitability, and Value

Cody Normitta Porter, Bryony Jerome, Daniel Lawrence, Mircea Zloteanu, April Smith

Employment is an important determinant of psychological, social, and economic wellbeing, yet individuals with mental health disorders often face barriers to workforce participation. This study examined the impact of mental health disclosure on perceptions of trustworthiness, job suitability, and value to the company, focusing on Major Depressive Disorder (MDD), Emotionally Unstable Personality Disorder (EUPD), and schizophrenia. Using experimental vignette methodology, 330 participants evaluated a job candidate bef …

19.08.2026journal-article

International Journal of Innovative Science and Research Technology

Therapeutic Architecture and War Trauma: A Literature Review Toward the Design of a Psychosocial Rehabilitation Center

Bucyedusenge Elizabette, Mahamat Talba, Bwemba Charles, Youssoufa S., Ndongo Jean Paul, Mbessa Michel

Architectural design bears a major responsibility in creating health spaces dedicated to the reconstruction of victims of conflict. Rehabilitation centers, conceived for individuals with a fragile psyche, require calm and regenerative environments that foster dignified social reintegration. This article presents a systematic literature review structured around four interconnected axes: the foundations of architectural programming; the historical and spatial principles of therapeutic architecture; the neurobiologica …

19.08.2026journal-article

World Journal of Psychiatry

Post-interventional anxiety and depression in patients undergoing endovascular therapy for acute ischemic stroke: A retrospective cohort study

Chao Yu, Yu-Hao Ding, Yu-Yi Xie, Jun-Jie Shao, Jing-Li Wang

BACKGROUND Endovascular therapy (EVT) has revolutionized the management of acute ischemic stroke (AIS) caused by large-vessel occlusion, significantly improving functional outcomes. However, the psychological sequelae following EVT, particularly anxiety and depression, remain insufficiently characterized. A clearer understanding of the prevalence and predictors of post-interventional anxiety and depression is essential for delivering comprehensive stroke care. AIM To evaluate the prevalence, severity, and risk fact …

19.08.2026journal-article

Acta Ophthalmologica

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

Koen A. van Overdam, J. Sebag

Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical variability of PVR. We propose an integrative framework in which PVR is conceptualised as a biological process arising from the interaction of three interdependent pathways: …

19.08.2026journal-article

Ear & Hearing

Spectro-Temporal Modulation Sensitivity Prospectively Predicts Speech-in-Noise Recognition in Cochlear Implant Users

Julia Erb, Malte Wöstmann, Jens Kreitewolf, Jan Peter Thomas, Christiane Völter, Jonas Obleser

Objectives: For cochlear implant (CI) patients, reliable predictors of speech outcome are desirable. In this longitudinal study, we examined the contributions of spectro-temporal sensitivity to successful speech recognition following cochlear implantation. Design: We assessed N = 46 recently implanted adult patients shortly after CI activation (T1) and 6 months later (T2) with an adaptive ripple discrimination paradigm where dynamic ripples varied around the temporal rate of 4 Hz and spectral scale of 0.5 cyc/oct. …

19.08.2026journal-article

Current Treatment Options in Neurology

Prism Therapy and Surgical Intervention for Oscillopsia

Elizabeth M. Bolton, Nicholas J. Volpe

Abstract Purpose of Review The purpose of this article is to present a critical appraisal of current therapeutic and surgical strategies for patients with nystagmus and associated oscillopsia. Different forms of nystagmus and associated oscillopsia as well as evidence supporting successful use of prism and surgical treatment of these patients are considered. Recent Findings Low power yoked prisms are effective and under-utilized in the treatment of infantile nystagmus syndrome (INS). Surgical treatments for INS and …

19.08.2026journal-article

Exploration of Targeted Anti-tumor Therapy

Mitochondrial checkpoint for interferon responses in macrophages

Andreas O. Mieland, Oliver H. Krämer

A functional immune system is a key antagonist of cancer cell growth. Cytokines such as interferons (IFNs) promote the onset of inflammation, turn cells into an anti-viral state, and shape the dynamic tumor-immune cell interactome. Recent work illustrates how type I IFNs contribute to the resolution of inflammatory conditions. This involves macrophage-mediated efferocytosis for the clearance of apoptotic cells and the intrinsic capacity of type I IFNs to restrict their own autocrine signaling loops via the IFN-stim …