Frontiers in Endocrinology
Effect modification by fatty liver in the association between triglyceride-Glucose index and new-onset hypertension: a large health-examination cohort study
Background The triglyceride-glucose (TyG) index is a simple surrogate marker of insulin resistance. Whether baseline fatty liver modifies the association between TyG and incident hypertension has not been evaluated in large longitudinal cohorts. Methods This retrospective cohort study included 66,664 adults without hypertension at baseline who underwent routine health examinations and follow-up. The TyG index was calculated from fasting triglyceride and fasting glucose concentrations and analyzed as both a continuo …