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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
11.08.2026journal-article

Indian Journal of Nephrology

Declining Kidney Function Is Associated With Podiatric Risk Among People With Type 2 Diabetes: A Cross-Sectional Observational Study.

Sivashankari Selva Elavarasan, Vijay Viswanathan, Satyavani Kumpatla

Background Chronic kidney disease (CKD) is related to the development and progression of diabetic foot ulcers (DFU). The aim was to assess the relationship between the International Working Group on Diabetic Foot (IWGDF) podiatric risk (PR) score and kidney function based on KDIGO among people with type 2 diabetes (T2D) in the Indian context. Materials and Methods In this cross-sectional observational study, data from 5,972 participants from 2022–2025 were included and categorized based on IWGDF PR and KDIGO catego …

11.08.2026journal-article

Canadian Journal on Aging / La Revue canadienne du vieillissement

An Analysis of Bi-directional Associations Between Self-Reported Residual Hearing and Loneliness: Findings from the Canadian Longitudinal Study on Aging

Julie Beadle, John Best, Lorienne Jenstad, M. Kathleen Pichora-Fuller, Paul Mick, Mélanie Levasseur, Mathieu Hotton, Brenda T. Poon, Jeff A. Small, Jaimie Borisoff, Gloria Gutman, Andrew Wister

Abstract This study examined the longitudinal associations between self-reported residual hearing and loneliness, and whether associations differed by age and sex. Using comprehensive cohort data from the Canadian Longitudinal Study on Aging (CLSA; n = 30,097 at baseline), cross-lagged path models (CLPMs) assessed associations across three timepoints (Baseline, Follow-Up 1 [FU1], and FU2). Among females 45–64 years, we observed statistically significant bi-directional associations (hearing to loneliness β = .018, p …

11.08.2026journal-article

Frontiers in Aging Neuroscience

Trajectory-based identification of cognitive-performance phenotypes across adulthood from psychophysiological testing

Alexander E. Zapryalov, Sergey V. Stasenko, Nadezhda A. Chumankina, Danila D. Shashnin, Maria V. Vedunova

Background Multidimensional psychophysiological batteries reveal substantial inter-individual variation in processing speed, accuracy, memory, executive control, and visuospatial performance. Because the present sample is predominantly young to middle-aged, the analysis is framed as adult cognitive-performance phenotyping rather than identification of clinical cognitive-aging stages. Methods We analyzed a cross-sectional convenience sample of 1,117 adults (age 18–78 years; mean 31.4 ± 12.0 years; 65.8% women) asses …

11.08.2026journal-article

Frontiers in Immunology

Aging-associated immune and stromal programs mark interferon- and remodeling-linked spatial contexts in psoriatic skin

Xuejingzi Wu, Mengwen He, Hongxiang Chen, Lu Gan

Introduction Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by spatially organized epithelial, stromal, vascular, and immune interactions. Although aging is associated with inflammatory activation and tissue remodeling in skin, it remains unclear how aging-associated transcriptional programs are positioned within psoriatic tissue architecture and whether stromal cells with senescence-associated features retain inflammatory responsiveness. Methods We integrated a normal aging human sk …

11.08.2026journal-article

Frontiers in Aging Neuroscience

Machine learning-based radiomics modeling of combined subcortical nuclei from quantitative susceptibility mapping for Parkinson's disease diagnosis

Fudong Wen, Jiawei Hu, Yubing Yang, Yue Su, Xinyu Song, Yuan Tian, Yupeng Wang

Background Quantitative susceptibility mapping (QSM) enables non-invasive assessment of brain iron deposition in Parkinson's disease (PD), yet existing radiomics studies have predominantly focused on single subcortical nuclei, without systematically evaluating whether combining multiple regions improves diagnostic accuracy. Methods A total of 59 PD patients and 73 healthy controls underwent QSM. Radiomic features were extracted from the substantia nigra (SN), caudate nucleus (CN), globus pallidus (GP), red nucleus …

11.08.2026journal-article

Transforming Government: People, Process and Policy

Who benefits from trustworthy AI? Public value and citizen legitimacy in urban generative AI governance

Nagwan AlQershi, Ramayah Thurasamy

Purpose The growing deployment of generative artificial intelligence (GenAI) in urban governance has intensified global debates on trustworthy AI. However, existing research remains largely technology-centric and offers limited empirical insight into how citizens perceive trustworthy AI and how these perceptions are translated into policy legitimacy. Addressing this gap, this study aims to examine how and for whom trustworthy AI generates legitimacy by analysing the mechanisms through which perceived GenAI trustwor …

11.08.2026journal-article

Gerodontology

Unmet Dental Care Needs Among Older Koreans

Mina Kim, Kyeongmin Jang

ABSTRACT Objective To examine predisposing characteristics, enabling resources, need‐related factors, and health behaviour or service‐use indicators associated with unmet dental care needs among Korean adults aged ≥ 65 years, using Andersen's Behavioural Model of Health Services Use as an organizing framework. Current Knowledge Previous Korea National Health and Nutrition Examination Survey (KNHANES)‐based studies have identified socioeconomic, geographic, and oral health‐related correlates of unmet dental care nee …

11.08.2026journal-article

Frontiers in Rehabilitation Sciences

Embodied robots in rehabilitation-oriented interventions for older adults with disability or cognitive impairment: a scoping review

Wen Xu, Xian Zhou, Yu Zeng, Sixuan Han, Yanyan Hong

Background Robots are increasingly used in later-life care. However, existing reviews often combine applications such as companionship, telepresence, medication support, monitoring, psychosocial support, traditional AI, and rehabilitation within a single body of evidence. This conceptual overlap makes it difficult to interpret the rehabilitation-specific evidence base. Objective This study aimed to map empirical studies on embodied robots used in rehabilitation-oriented interventions for older adults with disabilit …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Understanding How Older Adults Comprehend Simple Comparative Sentences in a Predicate-Final Language

Jimin Park, Seunghun J. Lee, Jee Eun Sung

Purpose: This study examined the effects of aging on the comprehension of simple comparative sentences in a predicate-final language. Additionally, we explored individual variability among older adults by categorizing them based on chance-level performance. Method: A total of 221 participants completed a sentence–picture matching task involving simple comparative constructions, which were manipulated by word order (comparee-first, standard-first). Response accuracy and response time (RT) were analyzed across age gr …

11.08.2026journal-article

Journal of Gerontology and Geriatrics

UK Consensus on Comprehensive Geriatric Assessment Screening for Older People with Cancer—CRANE

Tania Kalsi, Danielle Harari

UK cancer waiting-time standards inadequately address the complex needs of older patients, and no standardised, implementable comprehensive geriatric assessment (CGA) case-finding framework exists for this population. Using a nominal group technique involving clinicians and advocates, a consensus was reached to develop the Cancer Risk Assessment and Needs Evaluation (CRANE) CGA case-finding framework. CRANE was designed to be completed in 10–15 min for patients aged 70 and over, incorporating ten key domains, inclu …

11.08.2026journal-article

Frontiers in Medicine

Effect of rapid antiretroviral therapy initiation on loss to follow-up, virologic failure, and immunologic failure among people living with HIV under the treat-all policy in China: a retrospective cohort study (2016–2023)

Shuanglian Ao, Yan Zheng, Liuying Yang, Zongyu Nie, Peng Li, Hai Long

Introduction Since 2016, China has fully implemented the Treat-All policy, which eliminated the CD4 cell count threshold and ensures timely antiretroviral therapy (ART) for all people living with HIV (PLWH). This study aimed to evaluate the impact of rapid ART initiation ( ≤ 7 days post-HIV diagnosis) versus delayed initiation on loss to follow-up (LTFU), virologic failure, and immunologic failure among PLWH. Methods This study enrolled newly diagnosed, ART-naive adult PLWH in Guizhou Province, China, between 2016 …

11.08.2026journal-article

Metabolites

Macronutrient-Based Dietary Patterns and the Risk of Muscle Mass Decline in Middle-Aged and Older Adults: A Prospective Community-Based Cohort Study

Yuji Jeong, Seok-Won Son, Se-Hong Kim, Ha-Na Kim

Background/Objectives: Loss of skeletal muscle mass is linked to functional decline and adverse health outcomes. Evidence on long-term associations between macronutrient-based dietary patterns and muscle mass decline remains limited. This study examined this association in a prospective cohort of Korean adults aged 40–69 years. Methods: Participants were categorized into four groups by macronutrient energy proportion: high-carbohydrate (HCHO, carbohydrate > 65% of total energy), high-fat (HF, fat > 30%), high-prote …

11.08.2026journal-article

Uzhhorod National University Herald. Series: Law

The Ukrainian people as participants in law-making

A. M. Kolodiy, O. A. Kolodiy, A. I. Khalota

This article presents a comprehensive study of the legal nature of the Ukrainian people as participants in law-making activities within the context of the development of a democratic, constitutional and social state. It analyses the constitutional and legislative foundations of the Ukrainian people’s participation in the exercise of public authority, particularly in the sphere of adopting normative legal acts. Particular attention is paid to the provisions of the Law of Ukraine ‘On Law-Making Activity’, which, for …

11.08.2026journal-article

University of Waterloo Journal of Undergraduate Health Research

Pathologizing Aging: Risks and Concerns with Botox in Youth

Fatima Fahlefi

The growth in preventative Botox for younger demographics as a treatment for wrinkles reflects a cultural shift where aging is no longer seen as a natural life process, but a medicalized condition that requires interventions. This paper argues that there are some serious concerns with this trend regarding safety, ethics, and autonomy which are important to tackle. Using medical and sociological perspectives, this paper highlights how there is a need for better regulations of off-label procedures in informal setting …

11.08.2026journal-article

Healthcare

Risk and Protective Factors for Suicidal Ideation and Attempts Among Older Adults in California, 2021–2024 Pooled Cross-Sectional Study

Kristen R. Choi, Gery Ryan, Sarah E. Choi, Luisa R. Blanco

Background/Objectives: Older adults have high rates of suicide, but there is little research on age-specific correlates of suicide. The purpose of this study was to examine risk and protective factors for suicidal ideation and attempts across adult and older adult age groups in a racially diverse sample. Methods: Using a cross-sectional analysis of California Health Interview Survey (CHIS) data from 2021 to 2024 (N = 92,397) linked with 2020 CDC/ATSDR Social Vulnerability Index data, the analytic sample was 64,263 …

11.08.2026journal-article

The Journal of Cardiovascular Aging

Current status and global trends in self-care among patients with heart failure: challenges and opportunities

Barbara Riegel, Christopher S. Lee, Tiny Jaarsma, Anna Stromberg

Self-care effectively improves outcomes in adults with chronic conditions such as heart failure (HF). Yet engaging patients in self-care maintenance, self-care monitoring, and self-care management has proven to be difficult for patients and providers. In this review we define self-care as a decision-making process involving the choice of behaviors that maintain physiologic stability and the response to symptoms when they occur. The three core self-care behaviors of maintenance, monitoring, and management are define …

11.08.2026journal-article

Healthcare

Somatic, Psychiatric and Neurodevelopmental Comorbidities in People with Autism Spectrum Disorder (ASD): A Narrative Review

Emma Dando, Juergen Hahn, David A. Geier, Athena Whiteley, Paul Whiteley

Background/Objectives: Autism spectrum disorder (ASD) is currently singularly described as a behaviourally defined neurodevelopmental diagnosis with symptoms affecting social communication and social understanding alongside the presence of restricted patterns of behaviour. Wide, and often very personal, variations in symptom intensities and differing developmental trajectories, reflective of large heterogeneity, are an important feature of the label. ASD carries enhanced risks for multiple over-represented, sometim …

11.08.2026journal-article

Frontiers in Public Health

Prevalence and associated factors of cognitive frailty in older adults with heart failure: a systematic review and meta-analysis

Min Cheng, Jing Zhao, Juan Hu

Objectives To explore the prevalence and associated factors of cognitive frailty in older adults with heart failure. Design A systematic review and meta-analysis. Methods We systematically searched China National Knowledge Infrastructure (CNKI), Wanfang Data, the VIP Database, SinoMed, PubMed, Web of Science, Embase, the Cochrane Library and Scopus from their inception to March 30, 2026. Results A total of 22 studies involving 8,892 older adults with heart failure were included. The meta-analysis showed that the po …

11.08.2026journal-article

Frontiers in Health Services

Perceived feasibility of peer-delivered mental health and psychosocial support interventions for people living with HIV/AIDS at Ryan White-funded clinics in the southeastern United States: a Consolidated Framework for Implementation Research study of health care worker perspectives

Caroline W. Kokubun, Sophia C. Garbarino, Celeste K. Ellison, Benjamin G. Druss, Briana A. Woods-Jaeger, Ameeta S. Kalokhe, Jessica M. Sales

Background People living with HIV/AIDS and violence-related trauma histories (PLWH/T) may have unmet mental health needs due to high rates of mental disorders coupled with mental health provider shortages, as well as other barriers to care. Our prior work with PLWH/T in Metro Atlanta revealed a desire for peer-delivered mental health and psychosocial support (MHPSS) services, such as peer mentorship/navigation, peer support groups, cognitive behavioral therapy, and Psychological First Aid/Mental Health First Aid. M …

11.08.2026journal-article

Journal of the American Oil Chemists' Society

Early‐Stage Thermal Aging of Soybean Oil at 150°C: Coupling DGA ‐Derived Scission Gas Markers With GPC ‐Resolved High‐Molecular‐Weight Tail Growth

Haowei Lyu, Xinjie Wang, Zhaojun Xu, Xinlei Tu, Feng Feng, Chunshan Lu, Qingtao Wang, Qunfeng Zhang, Xiaonian Li

ABSTRACT Triglyceride‐based oils undergo concurrent chain scission and intermolecular coupling during high‐temperature exposure, resulting in time‐dependent redistribution of molecular weights and the formation of volatile/gaseous products. Here, refined soybean oil was thermally aged at 150°C for 0–96 h, and its degradation behavior was characterized using physicochemical indices (acid value, viscosity, and moisture), dissolved gas analysis (DGA) as scission‐related gaseous markers, and gel permeation chromatograp …

11.08.2026journal-article

Frontiers in Neurology

BrainAgeMS: protocol for a prospective comparative study of brain aging in healthy adults and people with multiple sclerosis

Sebastián Navarrete, Milena Capiglioni, Stefanie Marti, Lukas Pirpamer, Richard McKinley, Robert Hoepner, Alejandro León Betancourt, Piotr Radojewski

Biological brain aging can diverge substantially from chronological aging, particularly in chronic neurological conditions like multiple sclerosis (MS), where neuroinflammatory and neurodegenerative processes may accelerate age-related brain changes. This study aims to determine whether multipool Chemical Exchange Saturation Transfer (CEST) and T1 relaxometry at 7 T can serve as biologically grounded imaging markers of brain age in healthy adults and people with MS (pwMS). BrainAgeMS (NCT06221631) is a prospective, …

11.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

DELIRIUM PÓS-OPERATÓRIO NO IDOSO: FATORES DE RISCO, PREVENÇÃO E PROGNÓSTICO — REVISÃO NARRATIVA CRÍTICA COM GRADUAÇÃO DA EVIDÊNCIA

Caroline Pretto Sauter, Rafael Viana dos Santos Coutinho, Guilherme Valdemarca, Maisa Niehues, Amanda Novaes Rienda Soares

Introdução: o delirium pós-operatório é uma complicação neurocognitiva frequente em pessoas idosas e permanece subdiagnosticado, especialmente na apresentação hipoativa. Objetivo: analisar criticamente fatores de risco, estratégias preventivas e repercussões prognósticas, distinguindo evidência clínica direta, evidência indireta ou extrapolada e inferência fisiopatológica. Método: revisão narrativa crítica orientada pela SANRA, com atualização bibliográfica dirigida em PubMed/MEDLINE, Cochrane Library, SciELO e LIL …

11.08.2026journal-article

Journal of Monno Medical College

Knowledge on Diabetes Mellitus among the Rural People in a Selected Area of Manikganj District of Bangladesh

Afsana Mahjabin, Khondoker Mohammad Ali, Mushreen Islam, Md. Salahuddin Emdad, Raziya Sultana Niha, Hasan Toufik Imam, Shahima Sultana, Sk Md Muktadir Hasan, Mitali Hossain, Md. Mostafizur Rahman, A B M Maqsudul Haque

Background: Diabetes Mellitus (DM) is a disorder in which the body does not produce enough or respond normally to insulin causing blood sugar levels to be abnormally high. Objective: This study intends to assess the status of knowledge on Diabetes Mellitus of the people in a rural area of Manikganj district. Methodology: This was a descriptive type of cross-sectional study carried out in Andharmanik village, Boyra union, Harirampur upazila of Manikganj district during the period of May to October, 2025 in the Depar …

11.08.2026journal-article

Frontiers in Research Metrics and Analytics

Constructing a Bayesian neural network model for the cross-sectional classification of psychological distress among older adults: comprehensive analysis of humor styles, communication skills, and physical activity experiences

Keishi Soga, Keita Kamijo, Takuji Kawamura, Akari Uno, Yasuyuki Taki

Objectives This study aimed to develop a model for the cross-sectional classification of psychological distress among older adults, using a Bayesian Neural Network (BNN) to examine the relationships among humor expressions, communication skills, physical activity (PA), and social PA experiences (with friends), and their effects on psychological distress risk. Methods A cross-sectional survey was conducted among 5,265 Japanese adults aged 65 to 89 years. The predictor variables included humor expressions, communicat …