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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Journal of Speech, Language, and Hearing Research

Evaluating the Validity of Visual Analog Scales for Measuring Intelligibility in Spontaneous Speech

Nathaniel Cline, Kris Tjaden

Purpose: The purpose of this study was to investigate the relationship between orthographic transcription and visual analog scale (VAS) intelligibility ratings across read and spontaneous speech in speakers with Parkinson's disease (PD), speakers with multiple sclerosis (MS), and healthy controls. Method: Forty-four speakers (20 PD, 20 MS, four healthy controls) provided read speech samples from the Speech Intelligibility Test and spontaneous monologue samples. Speech samples were mixed with multitalker babble and …

02.09.2026journal-article

Radiation

Theranostics in Pancreatic Neuroendocrine Neoplasms: From Molecular Imaging to Personalized Radionuclide Therapy

Takehiro Okabayashi, Ryo Inada, Motoyasu Tabuchi, Rika Yoshimatsu, Yuji Negoro, Akihito Nishioka

Pancreatic neuroendocrine neoplasms (PanNENs) are a heterogeneous group of tumors characterized by variable biological behavior and frequent overexpression of somatostatin receptors, making them ideal candidates for theranostic approaches. Over the past two decades, advances in molecular imaging and peptide receptor radionuclide therapy (PRRT) have fundamentally transformed the diagnosis and management of advanced PanNENs, establishing nuclear medicine as a central component of precision oncology. This review provi …

02.09.2026journal-article

Laryngoscope Investigative Otolaryngology

Noninvasive Speech Restoration After Total Laryngectomy Using Surface Electromyography: Pilot Study

Naresh K. Kaushal, Daniel C. Comstock, Peter C. Belafsky, Adolfo Ramirez‐Aristizabal, Lee M. Miller

ABSTRACT Objective To demonstrate the feasibility of restoring intelligible, own‐voice speech after total laryngectomy using noninvasive surface electromyography. Methods One post‐laryngectomy patient and one healthy reference speaker silently articulated a closed‐vocabulary corpus of 499 dates and times while surface electromyographic (sEMG) signals were recorded from a 20‐electrode face, jaw, and neck montage. A decoder mapped sEMG into speaker‐independent speech tokens, which a public token‐to‐speech stack conve …

02.09.2026journal-article

Renal Replacement Therapy

Association between serum soluble (pro)renin receptor level and lower limb amputation in hemodialysis patients

Yoshifumi Amari, Satoshi Morimoto, Noriko Morishima, Chikahito Suda, Choka Azuma, Hidenobu Okuda, Fumitaka Nakajima, Atsuhiro Ichihara

Abstract Background The (pro)renin receptor [(P)RR] is a multifunctional protein, and its soluble form [s(P)RR], generated by proteolytic cleavage, has been proposed as a biomarker reflecting tissue renin–angiotensin system activity. Patients on maintenance hemodialysis (HD) have a high burden of cardiovascular disease driven by accelerated atherosclerosis. Serum s(P)RR levels are associated with atherosclerosis progression independently of conventional risk factors, suggesting its potential as a novel cardiovascul …

02.09.2026journal-article

Journal of the American Veterinary Medical Association

Comparing compressed 2-dose and 3-dose melarsomine protocols in the era of adjunctive therapy: a randomized clinical trial of 168 dogs with heartworm disease

Linda S. Jacobson, Jessie L. Dyer, Adrienne Van Vlake, Brian A. DiGangi, Mirah A. Horowitz, Julie K. Levy

Abstract Objective To test the hypothesis that, when used with doxycycline, moxidectin, and prednisone, 2-dose melarsomine would be as safe and effective as 3-dose melarsomine. Methods A randomized clinical trial was conducted from April 2024 to December 2025, comparing compressed 2-dose and 3-dose melarsomine protocols. Dogs with Class 1 or 2 heartworm disease received sustained-release moxidectin, doxycycline, prednisone, and 2 or 3 injections of melarsomine. Melarsomine was administered on days 14 and 15 (2-dose …

02.09.2026journal-article

Journal of Biomedical Optics

Single-fiber reflectance spectroscopy system using unmodified clinical laser fibers for tissue optical property recovery for photodynamic therapy treatment planning

Timothy M. Baran

SignificanceEstimation of tissue optical properties in workflow- and resource-constrained clinical settings is required to support photodynamic therapy (PDT) treatment planning, yet large-scale clinical translation remains limited by spectroscopy probe cost, complexity, and the need for probe-specific inverse models. Single-fiber reflectance (SFR) spectroscopy offers a simple and low-cost option, but previous implementations relied on customized angle-polished fibers.AimThe objective was to develop a proof-of-conce …

02.09.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Associations of multiple core stability aspects with drop jump performance

Liang Guo, Meng Wu, Kaiqi Zheng, Xiaokun Gong, Zhongwei Yang, Li Li

Abstract Background Drop jump performance (DJ) is essential for many ball sports. Core stability (CS) contributes to trunk control and lower-limb capacity during jump movements. The objective of this study was to investigate the relationships between multiple CS aspects and DJ performance. Methods Eighteen male university basketball players were recruited from a university. Kinematic and kinetic data of DJ were collected using infrared cameras and force plates. Five tests—sit-ups (SU), trunk extensor endurance (EE) …

02.09.2026journal-article

Annals of Surgery

A Randomized Controlled Trial Evaluating Negative Pressure Therapy (NPT) to Reduce Wound Complications Following Major Lower Extremity Amputation

Paul J. DiMuzio, Cara M. Staley, Federico Biscetti, Dawn M. Salvatore, Babak Abai, Michael J. Nooromid, Roberto G. Aru, Scott Keith, Romeo B. Mateo, Nii-Kabu Kabutey, Ellen D. Dillavou

Objective: This study hypothesizes that negative pressure therapy (NPT) reduces wound-healing complications following major amputation. Background: Major lower extremity amputation carries a high incidence of incisional complications. NPT reduces these complications in other areas of the body, suggesting a benefit following amputation. Methods: Patients undergoing above- or below-knee amputation (AKA, BKA) were randomized in this multi-institution study into receiving NPT versus standard dressing. The primary endpo …

02.09.2026journal-article

Africa Journal of Nursing and Midwifery

Cultural Beliefs of Zulu Women During Pregnancy, Labour, and Postnatal Infant Care in the KwaZulu-Natal Province of South Africa

Mmbulaheni Ramulondi

Numerous ongoing cultural beliefs begin at birth and continue throughout various stages of life. Women continue to observe these beliefs not only because they are traditions, but also because they hold meaning for them. This study explores the cultural beliefs and practices of Zulu women during childbirth. One hundred and forty women living in northern Maputaland were purposively selected and interviewed. Descriptive statistics were used to analyse data. The results indicated that all participants in this study wer …

02.09.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Association between patellar height and spinopelvic alignment in a static posture: A cross-sectional observational study

Minbong Kang, Donghyun Kim

Background Altered patellar height is associated with abnormal patellofemoral joint mechanics and is considered a structural risk factor for pain and instability. Although patellar height has been primarily explained by local knee structures, the contribution of static spinopelvic alignment remains unclear. Objective To compare spinopelvic alignment according to patellar height and to explore whether pelvic and spinal alignment variables are independently associated with patellar height. Methods This cross-sectiona …

01.09.2026journal-article

Journal of Nursing Reports in Clinical Practice

Effect of mindfulness-based cognitive therapy on fatigue and the quality of life of patients with decompensated heart failure: A quasi-experimental study

Bahauddin Ahmadpour, Sina Valiee, Fatemeh Rafiei, Mokhtar Mahmoudi

The current study aimed to evaluate the impact of mindfulness-based cognitive therapy (MBCT) on fatigue and quality of life among patients with decompensated heart failure (DHF). This quasi-experimental study with a pretest–posttest control group design was conducted in two cardiology clinics in Saqqez and Baneh, Kurdistan Province, Iran. Patients were randomly allocated to two groups: intervention and control. In the intervention group, the effects of MBCT training were evaluated using the Demographic Information …

01.09.2026journal-article

Kidney Research and Clinical Practice

Exercise as an adjunctive therapy for patients on maintenance hemodiafiltration

Jessica L. F. Andrade, Ayden T. Heitmann, Miguel K. Rodrigues, Dave K. Marchand, Adelson M. Rodrigues, Bruno P. Biluca, Rene Freitas, Thiago Reis, Miguel A. Goes, Mayron F. Oliveira

Background: Fatigue and sedentarism are common in kidney disease and dialysis treatment. Although hemodiafiltration effectively removes solutes and improves mortality, the influence of exercise as an adjunct therapy on maintenance hemodiafiltration programs remains understudied. Methods: A multicenter 6-month study was assessed comparing individuals with chronic kidney disease enrolled in exercise training (exercise group) during dialysis (intradialytic vs. interdialytic) compared to usual care (control group). Phy …

2 Zitationen
01.09.2026journal-article

International Journal of Sports Physical Therapy

Shoulder Internal and External Rotator Strength Reliability and Validity in Healthy Adolescent Athletes

Katie Sloma, Garrett Robbins, John Arvesen, Ashley Erdman, Alex Loewen, Joshua Riesenberg, Ava Davis, Henry Ellis, Philip Wilson, Sophia Ulman

Background Handheld dynamometry (HHD) has been recommended in return-to-play (RTP) assessments following shoulder injuries; however, variations in testing methods limits interpretation of results. In contrast, isokinetic dynamometry is considered gold-standard for assessment of strength but is less accessible than HHD. Further assessment is needed to identify which shoulder HHD testing positions best reflect isokinetic dynamometry values and can be used to guide RTP practices in adolescent athletes. Purpose To comp …

01.09.2026journal-article

Obesity Science & Practice

Patient‐Reported Continuity of GLP‐1 Receptor Agonist Therapy

You Chen, Gracie Piantek, Xinmeng Zhang, Yubo Feng, Chao Yan, Jason M. Samuels, S. Trent Rosenbloom, Danxia Yu, Laurie L. Novak, Gitanjali Srivastava

ABSTRACT Objective Use of GLP‐1 receptor agonists is associated with significant weight loss in many individuals. Discontinuation is associated with weight regain. Patients' experience with this is not well characterized. This study describes the patient experience of continuity of care. Methods A cross‐sectional electronic survey was administered to adults identified from an academic medical center's electronic health records as having at least one GLP‐1 RA prescription in the preceding 6 years and a subsequent pr …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Teachers’ Experiences in Ensuring the Inclusion of Students with Special Needs in Primary Education

Shpresë Qamili

This qualitative research study aims to capture the attitudes of elementary school teachers regarding the inclusion of students with special needs in elementary education, the teachers’ knowledge of inclusive education as well as to analyze the strategies they use, the challenges they face, and their support needs during this process. To conduct this research, we used semi-structured interviews with 20 elementary school teachers. The data were analyzed using thematic analysis to identify the main themes that emerge …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Deciphering Masalili Weaving: An Ethnomathematical Approach to Enhance Mathematical Literacy in Southeast Sulawesi

Helisman -, E. Kus Eddy Sartono, Muthmainah -, Tinto Wahyu Kisworo, Fatia Rosyida, Yeyen Febrilia

The stagnation of mathematical literacy among students in regional Indonesia necessitates culturally resonant pedagogical interventions. This study examines the efficacy of integrating Masalili weaving, a traditional textile from Southeast Sulawesi, into the geometry curriculum to enhance mathematical literacy and student interest. Using a quasi-experimental design with a non-equivalent control group, 256 sixth-grade students were recruited. The experimental group received instruction via an ethnomathematics-based …

02.09.2026journal-article

Therapeutic Advances in Ophthalmology

Fluocinolone Acetonide Implant as a Baseline Therapy for Diabetic Macular Edema: Results from the Randomized Phase 4 NEW DAY Study

Michael A. Singer, Charles C. Wykoff, Christopher D. Riemann, Victor H. Gonzalez, Christina Y. Weng, Kamel Alkhatib, Scott Moody, Mary Pao

Summary This summary explains the findings of the NEW DAY study, which examined two ways of starting treatment for diabetic macular edema (DME). DME is an eye condition that can affect people with diabetes and can cause blurred vision or vision loss if not treated. In the 18-month study, adults with DME who had little or no previous treatment started therapy with either a single fluocinolone acetonide (FAc) implant or a series of aflibercept injections. The FAc implant is a small device placed inside the eye and is …

01.09.2026journal-article

Physiotherapia Croatica

Proprioceptivna neuromuskularna facilitacija u rehabilitaciji pacijentice s protruzijom intervertebralnih diskova

Marina Brizić

Uvod: Sjedilački način života, nedovoljna razina tjelesne aktivnosti i pretilost povezanisu s povećanim rizikom razvoja degenerativnih promjena kralježnice, uključujući protruzijuintervertebralnog diska. Takve promjene mogu biti praćene boli, smanjenom pokretljivošćui ograničenjima u svakodnevnom funkcioniranju, što može negativno utjecatina tjelesno i psihološko zdravlje te kvalitetu života pojedinca. Jedan od fizioterapijskihpristupa koji se primjenjuje u rehabilitaciji osoba s mišićno-koštanim poremećajimajest p …

01.09.2026journal-article

Disinfection affairs

Efficacy of antimicrobial therapy and topical disinfectants in the purulent surgery department of a multidisciplinary hospital

O.V. Mironenko, A.A. Tovanova, A.A. Panteleev, M.I. Podboronov

Presentation at the scientific-practical conference with international participation «Perspectives of disinfectology. Disinfection measures in emergency situations and in the territories of natural foci of infectious diseases» (September 22-23, 2026, Moscow)

01.09.2026journal-article

Journal of Orthopaedic & Sports Physical Therapy

CFT+ With a Subsequent Interdisciplinary Pain Management Program (IPMP) If Needed Versus IPMP Alone for Patients With Severe Disabling Chronic LBP: Pragmatic Patient-Blinded RCT With Economic Analysis

Henrik Bjarke Vaegter, Anne Smith, Jannick Vaaben Johansen, Irene Stegemejer, Kira Søndberg Fuglsang, Jesper Fredslund Pedersen, Liza Sopina, Rob Schutze, Peter O’Sullivan, Peter Kent, Gitte Handberg, Francis Fatoye, Kasper Ussing, Jonas Bloch Thorlund

OBJECTIVES: We aimed to determine whether, for patients with severely disabling chronic low back pain (cLBP), initiating care with cognitive functional therapy combined with psychologist support (CFT+) improved disability and pain, and was cost-effective compared with an interdisciplinary pain management program (IPMP) at 12 months. METHODS: We conducted a randomized controlled trial (NCT04399772) with concealed allocation, blinded patients, and intention-to-treat analysis. One hundred thirty-three adults with seve …

01.09.2026journal-article

Society for Art Education of Korea

Development and Application of a Generative AI–Human Collaborative Meta-Analysis Procedure: Focusing on Digital Art Therapy Research

Society for Art Education of Korea, Yunmi Park, Inwoo Park, Jeongwan Seo, Hyeryung Seo, Daekeun Park

Meta-analysis synthesizes evidence across studies but is time-consuming and susceptible to judgmental variation and data extraction errors. Although generative AI has been applied to individual meta-analytic tasks, few studies have proposed a human–AI collaborative framework with validation procedures for the entire process. To address this gap, this study proposes a six-stage meta-analysis procedure through human– AI collaboration and introduces a human-guided AI convergence process in which AI outputs are iterati …

01.09.2026journal-article

PAIN, JOINTS, SPINE

Statistical Outcome Profile of a Diaphragmatic Breathing-Based Rehabilitation Programme for Mechanical Low Back Pain: Pain, Disability and Core Stability at 9-Month Follow-up

Khushi Vishwakarma, Dr. Jafar Khan, Dr. Shilpi Kapoor, Dr. K. M. Annamali, Dr Reshma Khurana, Dr. Renuka Pal

Background: Diaphragmatic breathing is increasingly incorporated into rehabilitation for mechanical low back pain because the diaphragm contributes to both respiration and lumbopelvic stabilization. This paper was designed as an outcome-focused statistical analysis, with greater emphasis on the trajectory, magnitude, consistency, and clinical interpretation of changes in pain, disability, and core-stability performance. Methods: Thirty adults with mechanical low back pain received diaphragmatic breathing retraining …

01.09.2026journal-article

Military Medicine

Infectious complications of mine-explosive trauma: etiology of wound infections and principles of antimicrobial therapy (literature review)

D. A. Prokopovich, L. V. Lagun, D. A. Yakovlenko

Infectious complications remain the leading cause of mortality and prolonged hospitalisation in military personnel sustaining mine-explosive trauma (MET). The aim of this study was to analyse the current spectrum of infectious complications of MET, evaluate the aetiological structure of wound pathogens, and determine rational principles of antimicrobial prophylaxis and therapy. A systematic review of 18 scientific publications from 2012–2025 was performed. Infectious complications were found to develop in 27–35 % o …

02.09.2026journal-article

The Oncologist

68 LNK001 is a High-Fidelity AND-Logic-Gated CAR T Cell Therapy that Enables Precision Targeting of Clear Cell Renal Cell Carcinoma (ccRCC): Target Discovery and Validation for the ATHENA Phase 1 Trial

Alexander Bankovich, Bryan Smith, Colin Farrell, Angeles Estelles, Janette Sutton, Zeynep Wheeler, Kazuteru Hasegawa, Benjamin Bauer, Jakob McBroome, Diego Vargas-Inchaustegui, Regina Lin, Mark Wallet

Abstract Background Chimeric antigen receptor (CAR) T cell immunotherapies have shown exciting clinical benefits in hematologic malignancies, whereas challenges have persisted in addressing solid tumors. A key reason for the lack of success in solid tumors is on-target off-tumor (OTOT) toxicity that has previously occurred towards targets such as CAIX in ccRCC. New tools are required to enable precise targeting of malignant cells and sparing of normal tissues. We have developed Logic-gated Intracellular NetworK (LI …