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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Journal of the American Geriatrics Society

Identifying Factors Associated With Prolonged Hospitalizations for Community‐Dwelling Veterans Living With Dementia

Chelsea R. Perfect, Justine Seidenfeld, Kayla W. Kilpatrick, Karen M. Stechuchak, Caitlin B. Kappler, Juliessa M. Pavon, S. Nicole Hastings

ABSTRACT Background People living with dementia (PLWD) are more likely to be hospitalized and have longer hospital stays compared with the general population. Prolonged hospitalizations are associated with inpatient complications, functional decline, and mortality. This study aimed to identify patient‐level factors associated with prolonged hospitalizations for PLWD. Methods Secondary analysis of a stepped‐wedge, cluster randomized trial that enrolled community‐dwelling older adults hospitalized for at least 2 days …

02.09.2026journal-article

South African Journal of Economics

How many people are employed in South Africa?

Andrew Kerr, Amy Thornton, Peris Wachira

ABSTRACT The main labour market survey in South Africa is the Quarterly Labour Force Survey (QLFS) but the General Household Survey (GHS) also measures employment. We show that despite often identical sample designs and questions about employment, the GHS produces higher estimates of total employment from around 2012 than the QLFS, which finds more economic inactivity. The discrepancy in employment totals worsens substantially after Covid and the GHS also starts to report many more unemployed while the QLFS reports …

02.09.2026journal-article

Health Security

The Role of Parmedics in Addressing the Health Insecurity of Older Adults in Humanitarian Emergencies: A Systematic Review

Megan De Silva, Lloyd Denzil Christopher, Aidan Peters, Navindhra Naidoo

Older adults are disproportionately exposed to greater risk of harm and adverse outcomes in humanitarian emergencies. This systematic review explores and evaluates contemporary evidence on the role of paramedics in responding to humanitarian emergencies, with a specific focus on their ability to reduce the vulnerability potential for older adults. A systematic review of the literature was undertaken using Joanna Briggs Institute evidence summary and PRISMA guidelines. From an initial yield of 4,440 results, 16 sour …

02.09.2026journal-article

Pharmacy

Development and Validation of Digital Decision Aids to Support Medication Adherence in Older Adults: A Scoping Review

Ghada Elba, Shaheena Fakir, Rishabh Sharma, Halak Patel, Caitlin Carter, Tejal Patel

Introduction: The development of technology to support medication management and adherence among older adults is rising. Many of these technologies offer diverse features, which add complexity when making a choice. Evidence-based decision aids can inform decision-making in such situations. To inform the development of such a decision aid, it is necessary to review the literature on the development and validation of decision aids that impact medication adherence. Therefore, this study aims to review the available li …

02.09.2026journal-article

People and Nature

Buildings as accidental habitat: Where animals nest, sleep and forage

Bethany M. Kiss, Sarah A. Bekessy, Brandon Mak, Fabio Sweet, Georgia E. Garrard, Wolfgang W. Weisser, Casey Visintin

Abstract Animals have long inhabited human buildings alongside us, but our understanding comes from isolated studies, such as reports of a possum in the roof or a bat in our walls. What we lack is the building's perspective: which building features actually serve as habitat and for whom? We first conducted a literature review to identify building features used by wildlife and to develop a classification of architectural elements relevant to habitat use. We then analysed over a decade of wildlife rescue records from …

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02.09.2026journal-article

Diabetic Medicine

The effect of social determinants of health on use of diabetes‐related mobile health applications in older adults with type 2 diabetes

Damilola Adissa, Cody Makinson, Melissa A. Elafros, Kara Mizokami‐Stout, Eva L. Feldman, Brian C. Callaghan, Evan L. Reynolds

Abstract Aims Determine associations between social determinants of health (SDOH) and use of diabetes‐related mobile health (mHealth) applications in older individuals with type 2 diabetes. Methods We identified participants that self‐reported having type 2 diabetes who completed the National Poll on Healthy Aging, a nationally representative survey of older adults in the United States. Co‐primary outcomes were use of mHealth applications to (1) track diabetes medications and (2) track blood glucose levels. SDOH fa …

02.09.2026journal-article

Healthcare

Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia

Antea Krsek, Lana Sabati, Ivana Krajina, Zofia Nikola Lewandowska, Vlatka Sotosek, Lara Baticic

Dementia is one of the leading causes of disability and dependence among older adults and is increasingly encountered in patients undergoing surgery. As populations age and surgical interventions become more common, understanding the perioperative care of patients with pre-existing dementia has become an important clinical priority. Dementia is associated with reduced cognitive reserve, chronic neuroinflammation, synaptic dysfunction, blood–brain barrier impairment, neurotransmitter abnormalities, and cerebrovascul …

02.09.2026journal-article

BMC Psychology

Undiagnosed probable depression among middle-aged and older adults in China: a two-wave national comparison using CHARLS, 2011 and 2020

Yue Wu

Abstract Background Population based evidence comparing physician recognition of probable depression among Chinese middle aged and older adults across national survey waves remains limited. Methods Data were drawn from two waves of the China Health and Retirement Longitudinal Study (CHARLS), including 10,546 wave-specific observations from 8,754 unique respondents aged 45 years and older in 2011 and 2020. Probable depression was defined as a score of 10 or higher on the ten-item Center for Epidemiologic Studies Dep …

02.09.2026journal-article

PLANTS, PEOPLE, PLANET

Niche‐tracking as a collecting method: Habitat‐targeted search strategies for taxon‐focused botany

Lucas C. Marinho, Isabela M. Waga, Domingos Cardoso

Societal Impact Statement Biodiversity science depends on more than collecting plants—it depends on how we search for them. Although GPS and digital maps have transformed fieldwork, they can also encourage repeated visits to the same easy‐to‐access sites, leaving other habitats and populations unknown to science. This paper formalizes “niche‐tracking,” a well‐known practical approach in which botanists combine scientific knowledge with traditional and local ecological knowledge to track the conditions where target …

02.09.2026journal-article

arq.urb

Neurourbanismo, imagem sensorial da cidade e Aging In Place

Ciro Férrer Herbster Albuquerque, Zilsa Maria Pinto Santiago

Segundo a Organização das Nações Unidas, estima-se que, até 2050, 68% da população mundial viverá em áreas urbanas, sendo que 22% terá 60 anos ou mais. O neurourbanismo constitui uma abordagem interdisciplinar que articula conhecimentos da neurociência, do urbanismo, da psicologia, da arquitetura, dentre outras áreas, com o objetivo de investigar como o ambiente construído influencia a atividade cerebral, o comportamento humano e a saúde ao longo da vida. O presente estudo consiste em uma revisão integrativa da lit …

02.09.2026journal-article

British Journal of Community Nursing

Smoke and mirrors are making people cynical

Alison While

This article discusses the government's initiatives to make the NHS more efficient through digitalisation and reducing waiting lists, and explores the unintended barriers to care created by these moves.

02.09.2026journal-article

Journal of Alzheimer’s Disease

Cross-sectional associations of loneliness with plasma p-tau217 and neurofilament light chain in dementia-free older adults in the INSPIRE-T baseline cohort

Claudie Hooper, Emmanuel González, Leonor Nogueira, Julien Delrieu, Nicola Coley, Maria Soto, Bruno Vellas, Sophie Guyonnet, for the IHU HealthAge INSPIRE/Open Science study group

Background Loneliness is the subjective feeling of social isolation and evidence suggests that it increases the risk for cognitive decline and Alzheimer's disease (AD). However, studies examining the associations between loneliness and AD biomarkers are limited and inconclusive. Objective We sought to investigate the relationships between loneliness and plasma tau phosphorylated at threonine 217 (p-tau217) and plasma neurofilament light chain (NfL): peripheral biomarkers of central AD pathology. Methods This is a c …

02.09.2026journal-article

Physiologia

Changes in Cardiovascular Health and Functional Fitness Following Multicomponent Exercise Training in Community-Dwelling Older Women

Sandra Silva-Santos, Paula Rodrigues, Cidália Freitas, Joana Pinto, Raphael José Perrier-Melo, Manoel J. Rios

Background: Multicomponent exercise promotes healthy aging, but evidence in community-dwelling older women remains limited. This study examined pre–post changes in functional fitness and cardiovascular health following participation in a six-month multicomponent exercise program. Methods: Thirty-five community-dwelling older women (71.39 ± 6.82 years) participated in a quasi-experimental pre–post intervention study. Participants completed supervised multicomponent exercise sessions twice weekly for six months. Anth …

02.09.2026journal-article

Work, Aging and Retirement

Classical Theories in the Hands of the Everyday: Lay Perceptions of Aging Well and Retirement in Singapore

Bryan Y J Tan, Yan Mo, Qiushi Feng

Abstract For decades, gerontologists have competed to objectively define the ideal later life, often eliding the subjective perspectives of older adults. Yet, definitions of successful aging are only meaningful intersubjectively, making lay evaluations crucial to ground theoretical models in the realities they are meant to serve. Such gaps are consequential to the alignment of retirement policies and workplace arrangements with the experiences of older adults. This study explores Singaporean older adults’ lay evalu …

02.09.2026journal-article

Physiology International

Poor sleep quality is associated with blunted baroreflex sensitivity during stress cardiovascular reactivity in older adults

Laith Ashour, Batool Abuqudaira, Shaima Jaber, Lujain Badran, Mohammad Zaita, Raghad Alhawi, Alameen Dirar Jaber, Salam Aburumman, Mohammad Al-Shorman, Rima Heramas, Hazim Mohammad Abualganam, Sajeda Omar Salem, Akram Saleh

Abstract Objectives Poor sleep quality may contribute to autonomic dysfunction in older adults, but evidence regarding its effect on stress-associated baroreflex sensitivity (BRS), an important physiological indicator, is limited. Methods data were derived from the MIDUS 3 Biomarker Project (2017–2022). Stress-associated BRS was measured using the sequence method while participants are taking a math-task (used as a psychological stressor) to solve in prespecified limited time. Sleep quality was assessed via the Pit …

02.09.2026journal-article

Aging Clinical and Experimental Research

Association between the preoperative geriatric nutritional risk index and loss of walking independence 180 days after hip fracture surgery: A retrospective cohort study

Jiachen Ren, Mengyuan Liu, Keyao Yang, Cici Bai, Xu Ma, Zhishang Wang, Guoxin Dong, Yanbin Zhu, Xiuting Li

Abstract Background Malnutrition may impair recovery after hip fracture, but the association between preoperative geriatric nutritional risk index (GNRI) and postoperative walking outcomes remains unclear. We examined the association between GNRI and loss of walking independence (LWI) 180 days after hip fracture surgery. Methods This was a retrospective cohort study of patients aged 65 years and older who sustained a hip fracture and underwent surgery at a tertiary referral hospital between January 2021 and Decembe …

02.09.2026journal-article

npj Dementia

Reimagining biomedical science workflows in the age of large language models

Kaleigh F. Roberts, Srinivas Koutarapu, Justin Melendez, Eric C. Landsness, Justin T. Reese, Donald L. Elbert, Randall J. Bateman

Abstract Large language models (LLMs) are generative artificial intelligence (AI) models that are rapidly reshaping the practice of biomedical science. Their ability to synthesize literature, generate analytical code, and interface with multimodal data offers a new framework for accelerating discovery. Yet their integration into scientific workflows remains irregular, and the field lacks clear guidance for reliable and productive use. We review emerging evidence on researcher adoption, highlight common failure mode …

02.09.2026journal-article

Australian Occupational Therapy Journal

Developing an at‐home dementia rehabilitation intervention: An iterative qualitative codesign study

Clare Stephenson, Sophia Hadjimichael, Kasia Bail, Diane Gibson, Stephen Isbel, Michelle Bennett, Nathan M. D'Cunha

Abstract Introduction There is limited availability of community‐based rehabilitation for people with dementia. This study explored stakeholder perspectives to inform the design of an occupational therapy‐led at‐home dementia rehabilitation programme. Methods Four co‐design workshops were conducted over 6 months with 16 participants, including people with dementia, care partners and health‐care professionals. Transcribed workshop discussions underwent iterative thematic analysis to inform the final intervention com …

02.09.2026journal-article

The Journal of Aging and Social Change

“Outside We May Become Wrinkly but Inside We Are Growing Crumbly”

Liana Winett, Louise Dalingwater

Women’s health in both the United States and the United Kingdom lags that of men in clinical understanding, options, and access. Even some phenomena that exclusively affect women and which represent a near-universal experience, such as menopause, have historically received less attention than their ubiquity might suggest. Given that the governments of both nations have material influence over how health is perceived and addressed, we wished to explore whether and how menopause has been perceived as a national polic …

02.09.2026journal-article

Canadian Geriatrics Journal

Prevalence and Risk of Heart Failure Among Older Adults Experiencing Homelessness: A Systematic Review and Meta-Analysis

Peter M. Hoang, Josephine Ding, Laith Almsari, Jeswende Seedu, Riyad Asgarali, Yu Qing Huang, Charmaine De Castro, Paula Rochon, Maurita Harris, Kristina M. Kokorelias

Background Understanding the prevalence and risk of heart failure (HF) among older adults is crucial for informing the design and implementation of interventions and guiding equitable healthcare delivery. Methods A systematic search was conducted in MEDLINE, Embase, Cochrane Database of Systematic Reviews, CINAHL, and Web of Science from inception to April 2025. We included studies of adults aged 50 years or older experiencing homelessness. Outcomes included HF prevalence, risk of HF, and HF mortality. Screening, e …

02.09.2026journal-article

npj Dementia

Regulators of interferon-responsive microglia uncovered by Genome-wide CRISPRi screening

Amanda McQuade, Vincent Cele Castillo, Venus Hagan, Weiwei Liang, Thomas Ta, Reet Mishra, Olivia Teter, Layla Gomes, Bianca Gonzalez, Noam Teyssier, Kun Leng, Martin Kampmann

Abstract Microglia dynamically support brain health through the induction of specialized activation states in response to injury or disease. Activation of the interferon-responsive microglia (IRM) state has been identified across neurodevelopmental windows, age-related cognitive decline, and neurodegenerative diseases. Functionally, IRM have been linked to synaptic pruning, dead cell removal, and neuroinflammation, making this state critical to brain homeostasis. While the functional importance of this state is bec …

02.09.2026journal-article

Journal of Sleep Research

A Double‐Blind Randomised Controlled Crossover Trial of the Effect of Blue‐Enriched Ambient Light on Sleep in Older Adults With Sleep Disturbance: The CleverLights Study

Teha B. Pun, Craig L. Phillips, Nathaniel S. Marshall, Matthew Rahimi, Rick Wassing, Maria Comas, Angela L. D'Rozario, Camilla M. Hoyos, Delwyn J. Bartlett, Wenye Hu, Sharon L. Naismith, Sean Cain, Svetlana Postnova, Ronald R. Grunstein, Christopher J. Gordon

ABSTRACT Light interventions have been investigated for treating sleep disturbances in older adults; however, findings are mixed. This proof‐of‐concept trial investigated the effect of blue‐enriched ambient light on electroencephalographic (EEG) sleep in older adults with self‐reported poor sleep. Twelve participants (65.6 ± 8.7 years) were randomly exposed to two 72‐h in‐laboratory light conditions separated by 2 weeks. During the day, participants were exposed to either blue‐enriched light (intervention: melanopi …

02.09.2026journal-article

Frontiers in Aging Neuroscience

Knowledge structure and frontier trends of exercise interventions for Parkinson’s disease: a bibliometric and visualized analysis

Jiangxi Yang, Huangyan Li, Shiliang Hu, Yang Xu, Yeting Zhang

Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder with motor and non-motor manifestations. Exercise is increasingly integrated into the management of people with PD, yet the literature spans diverse intervention modalities, outcome domains, and mechanism-related topics. Objective To characterize publication growth, global collaboration, article types, keyword networks, thematic evolution, outcome domains, and emerging research fronts in exercise intervention research for PD. Methods En …

02.09.2026journal-article

Dietetics

Mitochondria-Targeted Nutraceuticals as Metabolic Adjuncts to Physical Rehabilitation in Older Adults with Sarcopenia or Frailty: A Narrative Review

Alessio Turco, Lorenzo Lippi, Francesca Uberti, Alessandro de Sire, Marco Invernizzi

Age-related skeletal muscle wasting, clinically expressed as sarcopenia and frailty, significantly limits the efficacy of physical rehabilitation due to an underlying cellular bioenergetic decline, mitochondrial dysfunction, and chronic inflammaging. This narrative review synthesizes current physiological and clinical evidence evaluating mitochondria- targeted nutraceuticals as targeted metabolic adjuvants to physical exercise in older adults. Comprehensive literature searches were executed across PubMed, Web of Sc …