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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
12.08.2026journal-article

BMC Geriatrics

Prevalence of behavioural risk factors and their combinations among older adults: cross-sectional results of the nationwide study Gesundheit 65+

Beate Gaertner, Grit Eckert, Judith Fuchs, Jennis Freyer-Adam, Anne Starker

Abstract Background Behavioural risk factors (BRFs) negatively impact health and well-being across life course, including older age. Data on their prevalence among older adults in Germany are scarce. This study examines prevalence of single BRFs — alcohol use, smoking, insufficient vegetable and fruit consumption, physical inactivity, and obesity — and identifies BRF combinations with a focus on sociodemographic disparities in adults aged 65 years and older. Methods The nationwide Gesundheit 65 + study (06/2021–04/ …

12.08.2026journal-article

International Journal For Multidisciplinary Research

Counselling Approaches fo Reducing Anxiety in People with Alcohol Use Disorder: A Narative Review

Saurabh Prajapati, Tranjali Sharma

Background: Anxiety and alcohol use disorder (AUD) frequently co-occur, and the two conditions can reinforce one another. Counselling-based interventions are widely used in this population, but the supporting evidence is scattered across the literature and varies considerably in strength. Objective: This narrative review summarises counselling approaches used to reduce anxiety among people with AUD and compares the strength of evidence supporting each approach. Methods: PubMed, PsycINFO, the Cochrane Library and Go …

12.08.2026journal-article

International Journal of Innovative Science and Research Technology

Post-Stroke Psychosis and Neuropsychiatric Disturbances in an Older Adult: A Diagnostic Challenge and Case Report

Miguel Angel Diaz Diaz, Valentina Salazar Maldonado, Nicolás Alejandro Contreras Diaz, Juan Manuel Alfonso Parada

Post-stroke neuropsychiatric disturbances may manifest as affective, cognitive, behavioral, or psychotic symptoms and may represent a diagnostic challenge, particularly when structural epilepsy coexists with brain lesions involving different vascular territories. We present the case of a 67-year-old man with a history of arterial hypertension, type 2 diabetes mellitus, and obstructive sleep apnea syndrome, who had experienced ischemic strokes in the territories of the right posterior cerebral artery and the left mi …

12.08.2026journal-article

JAMA Network Open

Differences in Cognitive Aging Assessments Associated With Retest Effects

Yan Wang, James Russell Pike, Jennifer A. Deal, Frank R. Lin, Nicholas Salvatore Reed, Emmanuel E. Garcia-Morales, Alison R. Huang, Douglas A. Jabs, Alden L. Gross

Importance Retest effects can inflate longitudinal cognitive test performance and complicate estimation of cognitive change. Whether retest effects influence estimated intervention effects in randomized clinical trials remains unclear. Objective To quantify the magnitude and heterogeneity of differences associated with retesting in longitudinal cognitive testing and examine whether accounting for retesting alters estimated treatment effects in the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) trial. Des …

12.08.2026journal-article

International Journal of Obesity

Adolescent weight gain trajectories and their associations with biological aging: a genetically informed study

Anni Pitkänen, Anna Kankaanpää, Emma Raitoharju, Saara Marttila, Leo-Pekka Lyytikäinen, Pashupati P. Mishra, Nina Mononen, Tuija Tammelin, Juha Mykkänen, Katja Pahkala, Suvi Rovio, Laura Joensuu, Miina Ollikainen, Jorma Viikari, Olli Raitakari, Terho Lehtimäki, Elina Sillanpää

Abstract Background High body mass index (BMI) in adolescence is associated with accelerated biological aging, which might predict the onset of obesity-related diseases before they develop. Genetic factors may shape both adolescent BMI and weight trajectories. Methods Participants were from the Young Finns Study ( n = 3 596, ages 3–18 at baseline), followed from 1980 to 2018–2020. Biological aging was estimated using DNA methylation based epigenetic clocks DunedinPACE (years/calendar year) and PC-GrimAge (years) at …

12.08.2026journal-article

Journal of Geriatric Psychiatry and Neurology

Plasma Biomarkers and Clinical Indicators for Identifying Mild Cognitive Impairment in Older Adults With Psychiatric Disorders

Camilla Elefante, Maria Francesca Beatino, Daniela Marro, Andrea Coccoglioniti, Cosimo Lazzerini, Andrea Pacini, Ani Gasparyan, Esther Caparrós, Lucia Petrozzi, Gabriele Siciliano, Zahinoor Ismail, Lorenzo Lattanzi, Filippo Baldacci, Roberto Ceravolo, Giulio Perugi

Background Mild Cognitive Impairment (MCI) and Mild Behavioral Impairment (MBI) can be prodromal stages of neurodegenerative disease associated with plasma biomarkers of tau pathology and neuroaxonal damage. However, in psychiatric populations, the relationship between MCI, MBI and these plasma biomarkers remains unclear. Objective This study examined the association of MCI with plasma biomarkers of neurodegeneration (phosphorylated tau217 [p-tau217] and neurofilament light chain [NfL]), metabolic alterations, psyc …

12.08.2026journal-article

Theoretical Criminology

Generativity, legal consciousness and civic engagement among formerly incarcerated people

Justin M. Smith, Aaron T. Kinzel

Imprisonment and its collateral consequences after prison typically prevent political and civic engagement. Yet, some formerly incarcerated people counter this effect through leading and participating in organizational actions to transform the carceral system. Using in-depth interviews and an insider perspective, this study analyzes how generativity is associated with forms of civic engagement among formerly incarcerated people. Among this group of participants, generative relationships during and after incarcerati …

12.08.2026journal-article

Scientific Reports

Dynamic changes in physical frailty and associated factors among community-dwelling older adults in Chiang Mai: a prospective cohort study

Nida Buawangpong, Wachiranun Sirikul, Kanokporn Pinyopornpanish, Yanisa Samakarn, Wichuda Jiraporncharoen, Penprapa Siviroj

Abstract Silent and dynamic physical frailty causes rapid functional decline and dependency. This study aimed to determine risk factors for physical frailty progression or improvement. A prospective cohort study was conducted in Chiang Mai, Thailand, involving community residents aged 65 to 84. Participants were recruited in 2021 and were followed between May 2023 and September 2023. Physical frailty was assessed using modified Fried’s criteria. A generalized linear model was used to examine factors associated with …

12.08.2026journal-article

Journal of the American Geriatrics Society

Frailty and Five‐Year Mortality After TAVR in Patients Aged 75 Years and Older

Jérémie Huet, Mélissa Sabin, Thierry Le Tourneau, Thibaut Manigold, Anne‐Sophie Boureau

ABSTRACT Background Transcatheter aortic valve replacement (TAVR) is the standard treatment for older adults with symptomatic severe aortic stenosis. While cardiovascular predictors of long‐term mortality after TAVR are well established, the impact of geriatric factors beyond short‐term outcomes remains poorly defined. The main objective was to evaluate the association between geriatric factors and five‐year all‐cause mortality in patients aged 75 years and older undergoing TAVR. Methods This study is a single‐cent …

12.08.2026journal-article

Frontiers in Public Health

Nutritional status and functional capacity among people living with HIV in routine care: a retrospective cohort study

Louis Okeibunor Odeigah, Mary Olufunmilayo Ologe, Kazeem Adeola Oshikoya, Joseph Olusesan Fadare

Background Malnutrition remains an important concern among people living with HIV (PLHIV), even with widespread antiretroviral therapy (ART). Although ART has improved survival and long-term outcomes, undernutrition persists alongside increasing overweight and obesity, creating a dual nutritional burden that may complicate HIV care. This study described the nutritional status of adults receiving routine HIV care in a tertiary facility in Nigeria. Methods We conducted a retrospective cohort study using routinely col …

12.08.2026journal-article

InGente Americana

Implementación de dispositivo para envío de SMS a adultos mayores vulnerables en zonas rurales

Marlon Alexis Martinez Romero, Oscar David Gomez Ochoa, Ivan Camilo Nieto Sanchez

Introducción: El proyecto llevó a cabo un análisis integral de las condiciones geográficas, demográficas y socioculturales de la población adulta mayor campesina del corregimiento La Playa, en el municipio de Granada, Meta, Objetivo: Diseñar un dispositivo portátil de bajo costo para el envío de mensajes SMS en situaciones de emergencia. Metodología: Para ello, se evaluó la cobertura de redes móviles (GSM - 2G, 3G, 4G) y se seleccionó la tecnología más adecuada, considerando las limitaciones de conectividad y la ba …

12.08.2026journal-article

Healthcare

Changes in Emotional Regulation, Well-Being, and Pain Perception Following Music Therapy in People with Sensory Processing Sensitivity: A Non-Controlled Exploratory Study

Alicia Francisca Ponce-Valencia, Diana Jiménez Rodríguez, Leonor Alberola Amores, Alba Álvarez Pujante, Manuela Pérez-Chacón, Antonio Chacón, Paloma Echevarría Pérez

Background/Objectives: Highly sensitive persons (HSPs) are characterized by increased emotional and sensory responsiveness, which may predispose them to anxiety, emotional dysregulation, and sensory overload. Music therapy based on gong sound sessions has emerged as a complementary intervention aimed at promoting emotional well-being. This study analyzed immediate pre- and post-intervention variations in an adult population with sensory processing sensitivity. Methods: A quantitative, quasi-experimental, single-gro …

12.08.2026journal-article

Frontiers in Aging Neuroscience

MTHFR C677T and A1298C polymorphisms in dementia susceptibility: evidence from a meta-analytic investigation with disease-specific and ethnicity-stratified analyses

Yuyao He, Yandan Shi, Jinhua Hu, Xiyuan Wang, Jinqing Su, Ziyuan Yang, Zhihao Zhang, Sha Liao, Xiuxian Lu, Xiqi Zhu

Background Alzheimer’s disease (AD) and vascular dementia (VaD) have become significant global health challenges. Recent research evidence indicates a close comorbidity between AD and cerebral small vessel disease. The C677T (rs1801133, also known as c.665C > T) and A1298C (rs1801131) polymorphisms in the methylenetetrahydrofolate reductase ( MTHFR ) gene have been associated with both conditions, though conclusions vary across studies. Methods We conducted a systematic search of PubMed, Embase, Web of Science and …

12.08.2026journal-article

PLOS One

External validation of model predicting healthcare costs using cohort study-derived and claims-derived predictor variables in community-dwelling older adults

Lisa Langsetmo, John T. Schousboe, Allyson M. Kats, Brent C. Taylor, Cynthia M. Boyd, Kerry M. Sheets, Kristine Ensrud

Background In a pooled analysis of 4 prospective cohort studies linked with Medicare claims (2002–2011), claims-derived predictors and cohort-derived functional impairments and phenotypic frailty were associated with higher subsequent healthcare expenditures in community-dwelling beneficiaries. Objective Determine calibration and discrimination of published cost prediction models among a nationally representative sample of US community-dwelling older adults in an independent sample (external validation) and at a di …

12.08.2026journal-article

Frontiers in Aging Neuroscience

Semantic control across Alzheimer’s disease phenotypes: cognitive mechanisms and neural correlates

Pilar Armas, Alejandra O. Morcillo-Nieto, Sara E. Zsadanyi, Sonia Karin Marques-Kiderle, Júlia Filella-Mercè, Francesco Ciongoli, Isabel Sala, M. Belen Sanchez-Saudinos, Sara Rubio-Guerra, Nuole Zhu, Isabel Barroeta, Maria Carmona-Iragui, Ignacio Illán-Gala, Daniel Alcolea, Alberto Lleo, Juan Fortea, Stephanie M. Grasso, Marco Calabria, Javier Hernando, Elizabeth Jefferies, Matthew A. Lambon Ralph, Richard J. Binney, Alexandre Bejanin, Miguel A. Santos-Santos

Introduction Semantic cognition, our ability to understand meaning, relies on two distinct but interacting systems: one involved in knowledge representation and another in control processes. This control system is thought to comprise at least two mechanisms: controlled retrieval, which facilitates access to information relevant to a specific goal or context, and selection, which is engaged to resolve competition among multiple simultaneously active semantic representations. The present study aimed at understanding …

12.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Intelligibility of Emotional Speech in Chinese Older Adults: Effects of Age-Related Hearing Loss

Xinran Fan, Jing Zhang, Minhui Cai, Jiayi Wu, Runci Wang, Jingjing Guan, Hongwei Ding

Purpose: The intelligibility of speech with emotional prosody may decline with aging and hearing loss. In Mandarin Chinese, both lexical tone and emotional prosody rely on pitch variations, raising the possibility that emotional prosody modulates speech intelligibility. This study examined the effects of aging and age-related hearing loss on word recognition for Mandarin words spoken with different emotional prosodies. Method: Four groups participated: older adults with normal hearing (ONH; n = 35, 60–86 years of a …

12.08.2026journal-article

Polymer Composites

Combined Effects of Thermal Cycling Aging and Reinforcement Content on the Ball‐On‐Disk Wear of Additively Manufactured Polylactic Acid Composites

Sinan Fidan, Satılmış Ürgün, Nevin Gamze Karsli, Taner Yilmaz, Mustafa Özgür Bora, Mehmet İskender Özsoy

ABSTRACT This study focuses on the additive manufacturing of pure polylactic acid (PLA) specimens and milled glass fiber (GF)‐filled PLA composites under thermal cycling aging and wear tests. Wear tracks have been analyzed via 3D optical profiling and SEM imaging. DSC was used to characterize the material changes caused by thermal cycling rather than to determine friction‐induced heating or thermal softening during the wear tests. Factorial ANOVA has been used to evaluate the contribution of different factors. Rein …

12.08.2026journal-article

Frontiers in Public Health

Moving Barbados forward: a case for investment in exercise for geriatric health

Sanjay Seegobin, Cordelle Lazare, Leslie S. Craig, Sheldon Jones, Rhonda McIntyre

Barbados faces a geriatric health crisis: by 2060, older adults will comprise 29.1% of the population; NCDs cause 83% of deaths, and adults are inactive. While citizen group exercise programs exist, no government-funded, community-based geriatric exercise program operates at the national scale in Barbados or across the wider Caribbean region. Evidence shows exercise programs reduce fall risk and generate 36 to 127% return on investment, with the greatest financial benefit accruing for the oldest and highest risk pa …

12.08.2026journal-article

Frontiers in Public Health

Longitudinal trajectories of internet use, attitudes toward aging, and depression: a latent growth mediation model

Yunqian Zhou, Jie Qin, Na Cao, Linwei Yu

Objectives Whether Internet use affects depression in older adults in china via aging attitudes remains unclear. Moreover, few longitudinal studies have been conducted. Methods After excluding missing data, the final sample comprised 4,039 older adults (aged ≥60 years) from the 2018, 2020, and 2023 waves of the China Longitudinal Aging Social Survey (CLASS). Using latent growth modeling, we examined the proposed relationship between frequency of Internet use (IU), attitude toward aging (AA) and depression level (DE …

12.08.2026journal-article

International Journal of Environmental Research and Public Health

Determinants of PrEP Delivery Platform Choice in Adolescents and Young People: The Fast-PrEP Project in Cape Town, South Africa

Elzette Rousseau, Connor Bondarchuk, Keitumetse Lebelo, Luyanda Matsebula, Fiona Bennin, Pippa Macdonald, Carey Pike, Onesimo Vanto, Ntombovuyo Mathole, Lauren Fynn, Dvora Joseph Davey, Chelsea Coakley, Melissa Wallace, Linda-Gail Bekker

Background: Effective HIV prevention in South Africa requires implementing pre-exposure prophylaxis (PrEP) service delivery options responsive to adolescents and young people (AYP) with diverse characteristics and needs. We aimed to identify characteristics associated with AYP’s choice of PrEP initiation setting. Methods: Fast-PrEP is an ongoing phase 4 HIV prevention programme in Cape Town, South Africa. Oral PrEP (TDF/FTC) is offered to AYP (15–29 years) within sexual and reproductive health services from four co …

12.08.2026journal-article

JMIR Rehabilitation and Assistive Technologies

Usability and Functional Outcomes of the Obi3 Robotic Feeding Device Among People With Disabilities, Caregivers, and Providers: Mixed Methods Study

Andrea D Fairman, Ryan B Osal, Heather Keeton, Jonathan P Dekar

Background Loss of self-feeding ability due to severe bilateral upper extremity motor impairment (BUEMI) limits functional independence with a critical activity of daily living, increases medical risks, reduces social participation, and affects overall well-being. Robotic feeding devices are an emerging category of assistive technology. OObi3 is a third-generation, robotic feeding device, regulated in the United States as a Class I medical device and CE marked as a Class I device under the European Union Medical De …

12.08.2026journal-article

European Geriatric Medicine

Fall-Risk-Increasing drugs and falls in community-dwelling older adults: a prospective cohort study in a single Danish municipality

Thorbjørn Irskov Mortensen, Gustav Valentin Gade, Martin Grønbech Jørgensen, Lotta Seppala, Nathalie van der Velde, Tahir Masud, Jesper Ryg

Abstract Purpose Fall-risk-increasing drugs (FRIDs) are a significant and modifiable risk factor for falls in older adults. However, prospective data using robust fall ascertainment on specific FRID classes are scarce in community-dwelling populations. We aimed to investigate the association between individual FRID classes and both single and recurrent falls in older community-dwelling adults. Methods We analysed data from a Danish prospective cohort of 241 community-dwelling adults aged ≥ 75 years. Medication reco …

12.08.2026journal-article

PULMONOLOGIYA

Features of the bronchopulmonary system in elderly individuals: Aging and the respiratory system

A. D. Naumenko, A. L. Chernyaev, M. V. Samsonova

The elderly population is growing. It is projected to reach 20% or even higher percentage of the population by 2050. Respiratory system diseases rank second among the causes of death worldwide. To date, several signs of aging have been described which underlie the structural morphological and functional changes that lead to a gradual decline in the functions of the entire organism and disruption of adaptive mechanisms. This article describes some mechanisms of cellular senescence, provides morphofunctional characte …

12.08.2026journal-article

Journal of Alzheimer’s Disease

Progression from mild cognitive impairment to dementia in Alzheimer's disease: Whole cortex voxelwise functional connectivity analysis with multivariate distance matrix regression

Luiz Kobuti Ferreira, Eric Westman, Lars-Olof Wahlund, Rosaleena Mohanty, for the Alzheimer's Disease Neuroimaging Initiative

Background Differentiating individuals with mild cognitive impairment who convert to dementia due to Alzheimer's disease (MCI-C) from those who do not convert (MCI-NC) is increasingly important. Functional connectivity (FC) derived from resting state functional MRI (rs-fMRI) has been investigated as a potential biomarker. However, improved data analysis strategies are needed. One underexplored approach is pairwise voxel-to-voxel analysis. Objective To describe differences in FC between amyloid positive MCI-C and MC …