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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
12.08.2026journal-article

Sensors

Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults

Elodie Piche, Emeline Michel, Olivier Guerin, Etienne Gouraud, Frédéric Chorin

Background: Although dual-energy X-ray absorptiometry (DXA) is the reference method for measuring appendicular skeletal muscle mass (ASMM) and diagnosing sarcopenia, seated bioelectrical impedance analysis (BIA) may represent a practical alternative. As its validity remains still insufficiently documented in specific populations, the objective is to evaluate the agreement between seated BIA and DXA, and examine associations between phase angle (PhA) and physical performance in old adults. Methods: Fifty-nine old ad …

12.08.2026journal-article

Journal of Epidemiology and Community Health

Socioeconomic position and falls among middle-aged and older-aged adults: a systematic review with a life course approach

Frerik Smit, Marcia R Franco, Catherine Sherrington, Stéphane Cullati, Fiona Blyth, Anita van Zwieten, Saman Khalatbari-Soltani

Introduction Falls among middle-aged and older-aged adults are a significant public health concern. However, a holistic understanding of how different indicators of socioeconomic position (SEP) are associated with falls is lacking, particularly for SEP across the life course. Methods We systematically searched for observational studies analysing the association between at least one indicator of SEP and one fall outcome. Due to heterogeneity between included studies, results were narratively synthesised. Results Aft …

12.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

ARTIFICIAL INTELLIGENCE-DRIVEN FINTECH INNOVATIONS AND CIRCULAR ECONOMY TRANSITION: BRIDGING INNOVATION, INCLUSION, AND SUSTAINABLE IMPACT FOR PEOPLE AND PLANET

Suganthi Pais

As the need for sustainable development has grown, developing new and innovative technologies that help the move from a linear to a circular economy has been enhanced. The application of Artificial Intelligence (AI) and Financial Technology (FinTech) has become a game-changer with great potential to optimize resources, boost sustainable finance, and to drive environmentally responsible consumer behaviours. This research explores the impact of Artificial Intelligence (AI) powered FinTech Innovations on Circular Econ …

12.08.2026journal-article

Critical Care Medicine

Postintensive Care Frailty of Older Patients With Septic Shock: A Post Hoc Analysis of a Multicenter Randomized Controlled Trial

Ryo Yamamoto, Takahiro Yamanaka, Daiki Kaito, Akia Endo, Kazuma Yamakawa, Takashi Tagami, Yutaka Umemura, Junichi Sasaki

Objectives: Postintensive care frailty impairs quality of life in survivors of severe illness. While anabolic hormone deficiency and prolonged inflammation are considered key physiologic mechanisms, specific features associated with frailty progression remain unclear. This study aimed to elucidate clinical characteristics associated with frailty deterioration following recovery from septic shock in older adults. Design: Post hoc analysis of a randomized controlled trial. Setting: ICUs in Japan. Patients: Adults of …

12.08.2026journal-article

Frontiers in Aging Neuroscience

Joint effects of leukocyte-albumin ratio and hypertension are associated with multidimensional cognitive decline and Alzheimer’s disease risk in older adults: evidence from NHANES and a clinical AD validation cohort

Pan Gao, Yiming Chu, Mingjun Geng, Nannan Tian, Diandian Chen, Yingli Si, Heyang Liu, Peichang Wang, Jingrong Cao

Background Alzheimer’s disease (AD) pathogenesis involves complex interactions between neuroinflammation and vascular dysfunction. While leukocyte-albumin ratio (LAR) and hypertension are independently linked to cognitive decline, their joint associations with multidimensional cognitive impairment and AD risk remain understudied. Methods We analyzed two cohorts: 1,300 adults (≥ 60 years) from NHANES 2011–2014, and a clinical cohort (50 AD patients + 125 age-/gender-matched controls). LAR was calculated, hypertensio …

12.08.2026journal-article

Смоленский медицинский альманах

РОЛЬ ОБРАЗА ЖИЗНИ И ХАРАКТЕРА ПИТАНИЯ В ФОРМИРОВАНИИ СИМПТОМОВ ДИСПЕПСИИ У ЛИЦ МОЛОДОГО ВОЗРАСТА

В. С. Асадчая, А. И. Кускова, А. В. Типоченкова, Т. Н. Янковая

Анализ распространенности симптомов диспепсии выявил, что (n=53) 86% лиц молодого возраста имеют симптомы диспепсии. У девушек чаще встречается, чем у юношей чувство вздутия живота, чувство тяжести в верхней части живота после приема пищи, чувство раннего насыщения, отрыжка, изжога. У юношей чаще встречается чувство затруднения при глотании. Наиболее частым фактором, вызывающим диспепсию, является нарушение питания (употребление жирной пищи и fast food, нерегулярное питание и т.д.), в меньшей степени влияют наличие …

12.08.2026journal-article

Interdental Jurnal Kedokteran Gigi (IJKG)

Association of Oral Health Literacy Measured Using the Held-29 With Oral Health Status and Oral Health Behavior Among Independent Older Adults in Depok

Melissa Adiatman, Bernike Dasvitawati, Febriana Setiawati

Introduction: Oral health literacy is an important determinant of oral health, particularly among older adults who are vulnerable to oral diseases, tooth loss, and functional decline. This study aims to evaluate the association among oral health literacy, oral health status, and oral health behaviors among independent older people. Materials and Methods: This cross-sectional study involved 195 independent older adults aged 60 years and above in Depok. The subjects completed a self-administered questionnaire collect …

12.08.2026journal-article

Revista Enfermagem Atual In Derme

SINTOMAS NEUROLÓGICOS APRESENTADOS POR PESSOAS COM COVID-19 LONGA: REVISÃO DE ESCOPO

Bianca Cristina Galatti, Gustavo Diego Magno, Silvia Carla da Silva André Uehara

Objetivo: analisar os sintomas neurológicos desenvolvidos por pessoas com COVID-19 longa. Métodos: trata-se de uma revisão de escopo realizada nas bases de dados Web of Science, MEDLINE, LILACS, SCOPUS, SCIELO, Google Scholar e LitCovid. Para a inclusão, considerou-se artigos que abordaram: influência da idade, sexo, presença de comorbidades e situação vacinal. Resultados: foram selecionados nove estudos, que mostram os sintomas neurológicos mais comuns na COVID-19 longa como cefaleia, distúrbios do sono, fadiga e …

12.08.2026journal-article

Frontiers in Cardiovascular Medicine

Adjunctive qiliqiangxin capsule for heart failure in predominantly middle-aged and older adults: a systematic review and meta-analysis of randomized controlled trials

Shun Han, Xingxing Li, Xue Gao, Xuebin Chen

Background Heart failure (HF) is highly prevalent among middle-aged and older adults and remains associated with substantial residual morbidity and mortality despite guideline-guided treatment. Previous meta-analyses of Qiliqiangxin Capsule (QLQX) have mainly focused on general HF populations or patients with HF with reduced ejection fraction (HFrEF), with limited attention to age-related clinical applicability. Therefore, this study evaluated the adjunctive effects of QLQX in predominantly middle-aged and older st …

12.08.2026journal-article

Journal of Clinical Nursing

Exploring Pain Management for People Living With Dementia in Acute Care Settings Using the COM ‐B Framework to Guide Baseline Data Gathering

Faisal Mahama, Deirdre Harkin, Nicola Hayes, Mandy Doherty, Vivien Coates

ABSTRACT Aim To establish a comprehensive pre‐implementation baseline of pain management for people living with dementia (PLWD) in acute hospitals by exploring behavioural, contextual, organisational and clinical practice factors to inform the implementation of the DOTS approach. Background Pain is common yet frequently under‐recognised and inconsistently managed in PLWD in acute care. Behaviour change frameworks, such as COM‐B, may help identify determinants of practice and inform implementation strategies. Design …

12.08.2026journal-article

Community Dental Health

Impact of home-based professional dental cleaning on oral health and oral health-related quality of life in care-dependent older adults – a randomized controlled trial

Elisabeth Morén, Pia Gabre, Petteri Sjögren, Inger Wårdh, Pia Skott

Objective: The trial aimed to study the additive effect of domiciliary professional dental cleaning on root caries lesions (RCLs), oral hygiene outcomes and oral health-related quality of life (OHRQoL) in care-dependent older adults with in-home care that use high fluoride toothpaste, compared with oral care as usual for a year. Basic research design: Parallel-group evaluator-blinded randomized controlled trial. Clinical settings: Participants own home in Sweden. Participants: 194 care-dependent with in-home care a …

12.08.2026journal-article

Ageing International

How Dementia-Related Behavioral Changes and Characteristics of Family Relationship Determine the Growth and Decline of Supervision in Dementia Family Care

Andrés Oliva y Hausmann, Susanne Zank

Abstract Supervision is a burdensome aspect of family care for persons with dementia. For supervision that is both safe and bearable, potential dangers resulting from behavioral changes must be identified and tackled within the context of an ongoing family relationship. In this study, the development of the extent of supervision in the course of care is described from the perspective of family caregivers’ everyday care decisions. The influence of dementia-related behavioral changes, mobility, and relationship chara …

12.08.2026journal-article

Frontiers in Psychology

Subjective aging and psychological well-being in older adults: a narrative review and multilevel framework integrating perceptual, behavioral, and sociocultural pathways

Siyao Song, Kaiyang Jia, Bowen Hou

As the global population ages, understanding the psychological determinants of well-being in later life has become an important public health priority. A growing body of evidence suggests that how older adults experience, interpret, and evaluate their own aging—the domain of subjective aging—shapes psychological well-being. However, this literature remains fragmented across social gerontology, health psychology, and cultural psychology, with limited integration of perceptual, behavioral, and sociocultural mechanism …

12.08.2026journal-article

Frontiers in Aging Neuroscience

Stage-dependent clinical burden in hospitalized Parkinson’s disease with a positive bedside orthostatic hypotension screen: a retrospective cross-sectional analysis

Hengzhang Ma, Zhixiong Zheng, Caihua Chen, Mingyuan Xu, Qiaohui Zhu, Shenkun He

Background Orthostatic hypotension (OH) is common in Parkinson’s disease (PD), but what is known of its clinical associations comes from ambulatory or population-based cohorts assessed under protocolised or tilt-table conditions. The patients whom a routine bedside screen identifies on a general ward have not been described. Objective To characterise the modified Hoehn–Yahr (H–Y) stage distribution of hospitalized PD patients with a positive bedside OH screen, and to describe how clinical burden is distributed acro …

12.08.2026journal-article

Engineering Research Express

Blockchain, Internet of Medical Things and Artificial Intelligence based Medical Image Processing for Alzheimer Patient Monitoring

B Santhosh Kumar, P. Penchala Prasad, M. Raghavendra Reddy

Abstract Alzheimer’s disease is a neurodegenerative disorder that affects millions of individuals worldwide, making early diagnosis through Magnetic Resonance Imaging a significant clinical necessity. Existing medical image analysis techniques often suffer from limitations associated with inadequate preprocessing, reduced sensitivity to subtle abnormalities in the hippocampus and cortex, poor generalization across heterogeneous MRI acquisition systems, and insufficient mechanisms for secure medical data management. …

12.08.2026journal-article

Frontiers in Endocrinology

Association between sarcopenia and fall history in middle-aged and older adults: a multidimensional clinical analysis of nutritional status, bone health, and medication burden

Pin Wang, Jie Ke, Jingjing Wang, Jingyan Chen, Lei Zhang, Yan Yang

Background Sarcopenia has been associated with an increased risk of falls in older adults; however, this association may be influenced by nutritional status, bone health, comorbidity burden, and medication use. This study aimed to investigate the association between sarcopenia and fall history in middle-aged and older adults and to further identify sarcopenia-related components associated with fall history. Methods This cross-sectional clinical study included 298 middle-aged and older inpatients who underwent sarco …

12.08.2026journal-article

BMC Geriatrics

A new perspective in predicting fall risk in non-parkinsonian geriatric patients: the magnetic resonance parkinsonism index

Ilknur Seker Kaya, Kubra Bahar Baykan, Yilmaz Onal, Bugra Umut Kaya, Adil Aytac, Suleyman Emre Kocyigit

Abstract Objectives Falls are a major geriatric syndrome associated with significant morbidity and mortality in older adults. The Magnetic Resonance Parkinsonism Index (MRPI) is a neuroimaging biomarker reflecting brainstem structural alterations; however, its role in fall risk among non-parkinsonian older adults remains unclear. This study aimed to determine whether the MRPI is independently associated with recurrent falls in older adults. Methods This retrospective cross-sectional study included 250 adults aged ≥ …

12.08.2026journal-article

Dementia

“If She’s Anything Like Me…”: Exploring the Use of Verbally-Prompted Storytelling Techniques in Research With People Living With Dementia

Emma Conway, Ellen MacEachen, Laura Middleton, Carrie McAiney

Although approaches exist to address challenges in supporting participation of people living with dementia in research, these approaches are rarely evaluated, a critical step to understand their influence on promoting the engagement of people with dementia as research participants. This study sought to examine the influence of verbally-prompted storytelling techniques for engaging people with dementia in qualitative interviews. Participants (n = 12) completed a series of interviews utilizing both traditional semi-s …

12.08.2026journal-article

Journal of Diabetes Science and Technology

Analysis of Fasting Skin Spectra to Characterize Background Spectral Variance for Non-Invasive Glucose Sensing in People

Ariel B. Kauffman, Gary W. Small, Mark A. Arnold

Background: Background spectral variance (BSV) is a critical parameter that strongly impacts calibration models for noninvasive glucose measurements. To date, the ability to characterize such variances is limited. A protocol is described for collecting skin spectra under fasting conditions and using these spectra to characterize how the BSV impacts measurement accuracy. Methods: Transmission noninvasive skin spectra were collected over the combination region of the near infrared spectrum. These spectra were collect …

12.08.2026journal-article

Frontiers in Psychiatry

Dance-based exercise interventions in older adults: a narrative review examining the effects on depression, cognitive-motor function, mood, and quality of life

Shanshan Jin

Dance-based exercise has emerged as a promising non-pharmacological approach to support healthy aging by simultaneously engaging cognitive, motor, emotional, and social functions. This narrative review synthesizes evidence from randomized controlled trials and selected clinical studies investigating the effects of various dance modalities, including social dance, Latin dance, square dance, tango, and dance-based exergaming, on depression, cognitive-motor function, mood, and quality of life (QoL) in older adults. Ov …

12.08.2026journal-article

Advanced Neurology

Assessment of balance function in older adults with and without subjective cognitive decline

Yuting Hu, Haixin Tang, Jie Wu, Yanan Wang, Jie Xiang

As people age, their motor and cognitive functions gradually decline. Changes in balance function may emerge as early as the prodromal phase of cognitive decline. This study aimed to explore differences in balance abilities among older adults with and without subjective cognitive decline (SCD). This cross-sectional study included 31 healthy controls (HCs) and 31 older adults with SCD. Cognition was assessed using the following measures: the Mini-Mental State Examination, the Montreal Cognitive Assessment Scale, the …

12.08.2026journal-article

eLife

Aging-associated increase of GATA4 levels in articular cartilage is linked to impaired regenerative capacity of chondrocytes and osteoarthritis

Meagan J Makarczyk, Yiqian Zhang, Alyssa Aguglia, Olivia Bartholomew, Sophie Hines, Kate Li, Suyash Sinkar, Silvia Liu, Craig Duvall, Hang Lin

Although the causal association between aging and osteoarthritis (OA) has been documented, our understanding of the underlying mechanism remains incomplete. To define the regulatory molecules governing chondrocyte aging, we performed transcriptomic analysis of young and old human chondrocytes from healthy donors. The data predicted that GATA-binding protein 4 (GATA4) may play a key role in mediating the difference between young and old chondrocytes. Results from immunostaining and western blot showed significantly …

12.08.2026journal-article

Frontiers in Endocrinology

Body roundness index and its association with QUS-defined osteoporosis and bone mineral density in middle-aged and older adults: a cross-sectional analysis

Yucong Yang, Qichao Wang, Xiuwei Hou, Zhiwei Huang, Jing Bai, Bing He, Li Wu, Li Guo, Jirui Cai, Jin Wang, Qiaotao Xie, Haoran Wang

Objectives This study evaluated the association between Body Roundness Index (BRI) and QUS-defined osteoporosis, its discriminative ability, empirical cutoff, and subgroup heterogeneity in middle-aged and older adults. Methods We analyzed cross-sectional data from 1,444 community-dwelling adults aged 35–75 years. Osteoporosis was defined using tibial quantitative ultrasound-derived T-scores. Receiver operating characteristic curves assessed discrimination, restricted cubic splines examined dose-response relationshi …

12.08.2026journal-article

BMC Geriatrics

Prevalence of behavioural risk factors and their combinations among older adults: cross-sectional results of the nationwide study Gesundheit 65+

Beate Gaertner, Grit Eckert, Judith Fuchs, Jennis Freyer-Adam, Anne Starker

Abstract Background Behavioural risk factors (BRFs) negatively impact health and well-being across life course, including older age. Data on their prevalence among older adults in Germany are scarce. This study examines prevalence of single BRFs — alcohol use, smoking, insufficient vegetable and fruit consumption, physical inactivity, and obesity — and identifies BRF combinations with a focus on sociodemographic disparities in adults aged 65 years and older. Methods The nationwide Gesundheit 65 + study (06/2021–04/ …