EUVIMEDEuropean Health Evidence
Uhr 10/10Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Alter & Demenz · Seite 102

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

Journal of Burn Care & Research

A Matched Group Comparison of the Use of Autologous Skin Cell Suspension in Geriatric Burn Patients

Megan Newsom, Joseph Lewcun, Na Bo, Zachary Brown, Prabhu Senthil-Kumar, Michael Feldman

Abstract There is an increasing population of geriatric burn patients, and burns in this population are more morbid. Autologous skin cell suspension is an adjunct to autografting, which uses an 80:1 expansion of skin cells. The purpose of this investigation was to evaluate the ability of autologous skin cell suspension to augment wound healing in burn patients 65 years or older. We performed a single-center retrospective review of geriatric burn patients who underwent surgical treatment between January 2020 and Oct …

13.08.2026journal-article

Brazilian Journal of Medical and Health Sciences

Microbiota intestinal e suas relações com a doença de Alzheimer: uma revisão sistemática

Talles Vairo Magalhães

Esta revisão sistemática explora a relação entre a microbiota intestinal (MI) e a doença de Alzheimer (DA), uma condição neurodegenerativa caracterizada pelo acúmulo de placas βamiloides, neuroinflamação e disfunção da barreira hematoencefálica (BHE), levando a um declínio cognitivo progressivo e comprometimento da memória. Evidências sugerem que alterações na MI desempenham um papel relevante na patogênese da DA, tornando sua modulação uma estratégia terapêutica promissora. Com base nas diretrizes do PRISMA, foram …

13.08.2026journal-article

Information Technology & People

Determinants of pre-interaction swift trust and long-term adoption of care robots: the role of mind attribution and perceived similarity in eldercare robotics

Mahed Maddah, Shirin Hasavari, Shadi Esnaashari, Pouyan Esmaeilzadeh

Purpose The global eldercare crisis, driven by population aging and caregiver shortages, has accelerated interest in care companion robots. However, their integration into care settings depends partly on whether older adults are willing to trust unfamiliar robotic agents. Existing research has examined robot design, functionality and cultural acceptance, but has not fully integrated mind attribution and perceived relational alignment in explaining prospective trust and adoption intentions. This study therefore appl …

13.08.2026journal-article

Working with Older People

A community anchored integrated care pathway to address alternate level of care designation for older adults

Alicia Wickens

Purpose This study aims to examine Alternate Level of Care (ALC) pressures in Ontario as a health system design issue rather than solely a hospital flow problem, and to propose a Community-Anchored Integrated Care Pathway that addresses upstream determinants contributing to delayed transitions of care for older adults living with frailty. Design/methodology/approach This conceptual paper synthesizes evidence related to five upstream determinants of ALC pressures: early frailty identification, caregiver well-being, …

13.08.2026journal-article

Rehabilitation Counseling Bulletin

An Application of Rehabilitation Counseling Theory for Understanding Coping Among People With Alopecia Areata

Garrett E Huck, Yongsu Song, Kylee Kohlhoff, Emma Montero, Annika Covington, Shaina Baxter

Theories of rehabilitation counseling have enriched our understanding of individual responses to chronic disease and disability for nearly a century. Nevertheless, despite its prevalence and profound psychosocial impact, alopecia areata (AA) remains underrecognized in rehabilitation and health literature. This research aims to investigate the role of different coping styles on relationship-related and subjective quality-of-life outcomes among individuals with AA, considering Livneh’s conceptualization of psychosoci …

13.08.2026journal-article

Journal of Hypertension

Elevated urinary angiotensinogen excretion links incidence of chronic kidney disease among community-dwelling population: The Aging Kidney Study

Shun Yoshikoshi, Keisei Kosaki, Shoya Mori, Seiji Maeda, Makoto Kuro-o, Kunihiro Yamagata

Objectives: Activation of the intrarenal renin–angiotensin system (RAS) has been implicated in chronic kidney disease (CKD) pathophysiology. Although urinary angiotensinogen (AGT) is a noninvasive surrogate marker of intrarenal RAS activity, whether urinary AGT is associated with incident CKD remains unclear. We investigated the association between urinary AGT and incident CKD in community-dwelling adults without CKD. Methods: We conducted a prospective cohort study of community-dwelling adults without CKD. Urinary …

13.08.2026journal-article

PLOS One

Interventions involving young people for health equity targeting the fossil fuel industry’s practices and products: A realist review protocol

Thilagawathi Abi Deivanayagam, Sandie-Marie Szawlowski, Sufiyan Abdul-Qayum, Araceli Camargo, Angela Fonso, Rachel Isba, Shweta Narayan, Audrey Prost, May van Schalkwyk, Delan Devakumar

Background The fossil fuel industry’s practices and products create wide‑ranging harms to human health, with disproportionate impacts on communities already affected by structural disadvantage. Young people, particularly adolescents, are among those most affected by these harms, yet they are often excluded from health and climate decision-making. At the same time, youth-led initiatives to counter the fossil fuel industry’s practices and products are increasing globally. Despite this momentum, little is known about …

13.08.2026journal-article

Nursing Research

Subjective Cognitive Decline and Fear of Falling Among Community-Dwelling Racially Diverse Older Adults in Low-Income Settings

Renata Komalasari, Nikki L. Hill, Ladda Thiamwong

Background: Subjective cognitive decline (SCD) and fear of falling share similar mental health consequences (e.g. increased depression and anxiety), but limited research evaluates their relationships in racially diverse older adults living in low-income settings. Objectives: We examined associations of older adults’ SCD and SCD-related functional difficulties with fear of falling and the moderating effects of depressive and anxiety symptoms. Methods: A cross-sectional study, part of a larger clustered randomized co …

13.08.2026journal-article

Open Forum Infectious Diseases

Statin initiation and risk of serious respiratory infection: a population-based cohort study of older UK adults using linked health records

Adam J Streeter, Fergus Hamilton, Ian J Wellaway, Lauren R Rodgers, Sarah Walker, Stephen Mullin, André Karch, William Hamilton, William E Henley

Abstract Background While statins are typically prescribed to reduce the risk of cardiovascular diseases, they may also offer protection against influenza. We investigated the effect of statins on influenza and related respiratory outcomes in older adults not receiving influenza vaccination in the UK. Method We aggregated annual cohorts from 2010 to 2018 comprising UK patients registered in primary care within the UK Clinical Practice Research Datalink, aged ≥65 years on the1st September index date without influenz …

13.08.2026journal-article

The Gerontologist

A systematic review and meta-analysis of lifestyle interventions for informal caregivers of older adults: Effects on behavioral change, mental health, and physical health

Dara Kiu Yi Leung, Lucy Xi Lu, Yun-Han Wang, Yun-Lin Wang, Artemis Sze Kok Fung, Katrina Tingan Jin

Abstract Background and Objectives Informal caregivers of older adults often experience poorer lifestyle behaviors and elevated risks of physical and mental health problems. This systematic review and meta-analysis evaluated the effects of lifestyle interventions on behavioral, mental, and physical health outcomes among caregivers of older adults, and explored whether intervention characteristics influenced outcomes. Research Design and Methods Following the Preferred Reporting Items for Systematic Reviews and Meta …

13.08.2026journal-article

BMC Psychiatry

The association between childhood exposure to inter-parental violence and depression in middle-aged and older adults: an empirical analysis from China

Dongxu Li, Wenhui Li, Weile Zhang, Tianjiao Zhang, Zelin Liu, Min Su, Xi Guo

Abstract Background The association between exposure to inter-parental violence (IPV) and depression remains to be further explored. This study aimed to explore the association between childhood exposure to IPV and depression in middle-aged and older adults, and to explore the mediating roles between the two. Methods Using data from the 2011, 2013, 2015, 2018, and 2020 China Health and Retirement Longitudinal Study (CHARLS), and the 2014 Life History Survey Questionnaire. Generalized estimating equation was used to …

13.08.2026journal-article

Life

Comparative Analysis by Machine Learning of Geriatric Frailty and Alzheimer’s Disease Classification Using Independent Datasets

Lăcrămioara Luminița Apescaritei Apostol, Claudia Simona Ștefan, Mihai Grecu, Simona Moldovanu, Gabriela Isabela Verga, Mihaela Lungu, Gabriel Ioan Prada, Aurelia Romila

Frailty syndrome and Alzheimer’s disease are prevalent conditions in the elderly that are associated with aging, decreased quality of life, and a significant healthcare burden. Evidence for a relationship between physical frailty and neurodegenerative decline is accumulating. This study analyzed two independent datasets, a frailty dataset based on gait and mobility parameters and an AD dataset with clinical, functional and lifestyle variables, in order to evaluate and compare their classification performance using …

13.08.2026journal-article

npj Aging

Aging-induced hepatocyte CD44 drives IL6/STAT3 signaling that associates with impaired function of neighboring T cells

Armin Gandhi, Kathryn Lande, Kelly Yichen Li, Filipe A. Hoffmann, Michael LaPorte, Shirong Tan, K. Garrett Evensen, Benji Portillo, Marcos Garcia Teneche, Rouven Arnold, Adarsh Rajesh, Jessica Proulx, Shanshan Yin, Aaron Havas, Angela Liou, Allen Lee, Helene Martini, Xue Lei, Charlene Miciano, Qian Yang, Elizabeth W. Smoot, Sainath Mamde, Andrew Davis, Rebecca Porritt, Alessandra Sacco, João F. Passos, Kevin M. Tharp, Kevin Yip, Allen Wang, Bing Ren, April Williams, Susan Kaech, Peter D. Adams

Abstract Liver cancer incidences increase dramatically beyond 55 years of age, suggesting that age-associated changes contribute critically to tumor initiation. However, the mechanisms linking liver aging and cancer initiation remain incompletely defined. This study investigated the role of CD44, a marker of liver tumor-initiating cells (TICs), in age-associated liver pathophysiology. To define the role of CD44 in aged livers, we profiled CD44-expressing hepatocytes in young and aged livers by targeted and unbiased …

13.08.2026journal-article

PLANTS, PEOPLE, PLANET

Fonio ( Digitaria exilis and Digitaria iburua ) in Nigeria: Regional cultivation patterns, landrace diversity, and farmer knowledge for conserving a climate‐resilient indigenous cereal

Ishaq Muawiyya, Abubakar Bello, George P. Burton, Philippa Ryan, Maria S. Vorontsova

Societal Impact Statement Fonio ( Digitaria exilis and Digitaria iburua ) cereals are valued for their drought resilience, adaptability to poor soils, and cultural importance. In Nigeria, where both species are cultivated, fonio has declined due to labor‐intensive processing, lower yields, and changing livelihood choices. By documenting 21 landraces (15 D. exilis and 6 D. iburua ), this study highlights the need to conserve farmer‐managed diversity while improving processing and market opportunities. Strengthening …

13.08.2026journal-article

Journal of Enterprising Communities: People and Places in the Global Economy

Digital financial literacy, inclusion, and training as drivers of Muslim women’s entrepreneurial performance

Goso Goso, Harun Alrasyid, Mohamad Hazeem Sidik, Syamsu Alam

Purpose This study aims to develop and test an integrative framework examining how digital financial literacy, financial inclusion, entrepreneurial training and access to finance influence Muslim women’s entrepreneurial performance, with entrepreneurial self-efficacy as a mediator and socio-cultural norms as a moderator. Design/methodology/approach Survey data were collected from 441 Muslim women micro, small and medium enterprise entrepreneurs in Indonesia using purposive sampling. The proposed relationships were …

13.08.2026journal-article

Frontiers in Dementia

Diagnostic and treatment strategies in a memory clinic for older adults in a region with a predominantly low-income population

Patricia Solis, Ines Mintz, Nancy Medel, Zulma Sevillano, Julieta Lisso, Nicolas Irureta, Mauricio Federico Zalazar-Jaime, Brenda Giagante, Maria Carolina Dalmasso, Silvia Kochen

Background Early detection and interdisciplinary management of cognitive impairment are essential, particularly in socioeconomically vulnerable populations with limited access to specialized care. To address this need, a Memory Clinic was established in 2016 within the Argentine public healthcare system in Florencio Varela. This region reflects a condition of structural poverty, where 16.2% of the population lives in poverty according to Unsatisfied Basic Needs (UBN) and over 60% of residents lack essential service …

13.08.2026journal-article

BMC Geriatrics

Non-pharmacological interventions for older adults with mild cognitive impairment: an umbrella review

Diana C. Tiga-Loza, Edwing A. Urrea-Vega, Raquel Rivera-Carvajal, William A. Alvarez-Anaya, Jhosman A. Buitrago-Buitrago, Ana M. Hernández-Martínez, Paul A. Camacho-López

Abstract Background Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia in which preventive interventions may help delay cognitive decline. Multicomponent non-pharmacological interventions (NPTs) combining physical, cognitive, and psychosocial components have shown promising results; however, the available evidence remains heterogeneous. Objective Synthesize evidence from systematic reviews and meta-analyses (SRMAs) evaluating multicomponent, non-pharmacological interventions …

13.08.2026journal-article

Vaccines

The Epidemiological and Economic Burden of Vaccine-Preventable Respiratory Diseases Among Adults Aged 65 Years and Older in the Nordic Countries

Nicoline Weinreich Reinstrup, Renée Hangaard Gidsel, Terho Heikkinen, Anne Margarita Dyrhol-Riise, Lars-Åke Levin, Lars Jørgen Østergaard, Lars Holger Ehlers

Background: Despite the increasing availability of tailored vaccines, vaccine-preventable respiratory diseases (VPRDs), including influenza, respiratory syncytial virus (RSV), COVID-19, and pneumococcal disease (PD), continue to impose a significant health and economic burden. This study assessed the epidemiological and economic burden of VPRD among adults aged ≥65 across four Nordic countries (Denmark, Sweden, Norway, and Finland). Methods: Data on incidence, hospital admissions, and mortality were obtained from n …

13.08.2026journal-article

Frontiers in Nutrition

Serum 25-hydroxyvitamin D and cognitive performance in hospitalized older adults: a cross-sectional study from Central Poland

Ganna Kravchenko, Serena S. Stephenson, Julia Dmuchowska, Tomasz Kostka, Bartłomiej K. Sołtysik

Introduction Dementia constitutes a major and rapidly growing public health challenge worldwide. The identification of its risk factors and potential contributors has therefore become a major focus of research. This study aimed to investigate the association between serum 25(OH)D concentration and cognitive performance, as well as the odds of cognitive impairment and documented dementia in a hospitalized geriatric population. Materials and methods This cross-sectional study included 1,539 hospitalized individuals a …

13.08.2026journal-article

Journal of Clinical Medicine

Biologics in Older Adults with Chronic Obstructive Pulmonary Disease: A Narrative Review

Simone Scarlata, Alessio Marinelli, Panaiotis Finamore, Vitaliano Nicola Quaranta, Giulia Amoroso, Alessandra Tomasello, Claudio Sorino, Giovanna Elisiana Carpagnano, Nicola Scichilone, Silvano Dragonieri

Background: Chronic obstructive pulmonary disease (COPD) disproportionately affects older adults. While targeted biologic therapies have shown efficacy in type 2 eosinophilic endotypes, elderly patients remain underrepresented in pivotal clinical trials. This narrative review examines the pathophysiological rationale, efficacy data, and unique geriatric challenges of biologic therapies in older adults. Methods: A literature search was conducted in PubMed and Scopus for phase II and III randomized controlled trials …

13.08.2026journal-article

Physiotherapy Research International

Association Between Cervical Range of Motion and Swallowing Speed in Older Women After Total Hip Arthroplasty: A Cross‐Sectional Study

Katsuya Nakamura, Shinsuke Nagami, Akio Shimizu, Shinya Fukunaga, Shusaku Kanai

ABSTRACT Background and Purpose Total hip arthroplasty (THA) may induce acute alterations in spinopelvic alignment and compel the cervical spine to compensate for postural balance. Although these changes may biomechanically affect swallowing speed, the relationship between cervical range of motion (ROM) and swallowing speed in older adults after THA remains unclear. Therefore, this study aimed to investigate the relationship between cervical ROM and swallowing speed in older women after THA. Methods This cross‐sect …

13.08.2026journal-article

PLOS One

Achieving the triple endpoint of body weight reduction thresholds, systolic blood pressure reduction ≥5 mmHg and non-HDL cholesterol

Naveed Sattar, Reshmi Srinath, Luis-Emilio García-Pérez, Clare J. Lee, Chrisanthi A. Karanikas, Xinyue Chen, Arian Plat

Background Modest body weight reduction can greatly improve many health-related outcomes. In the SURMOUNT clinical trial program, once-weekly tirzepatide resulted in substantial body weight reductions in people with obesity, without and with type 2 diabetes. Objective This post-hoc analysis assessed the proportion of participants achieving body weight reduction thresholds (≥5%, ≥10%, ≥15%), systolic blood pressure reduction ≥5 mmHg, and non-high-density lipoprotein cholesterol (non-HDL-C)

13.08.2026journal-article

AGING MEDICINE

Beneficial Body Mass Index for Age‐Related Kidney Function in Males and Females

Lu Wei, Yao Ma, Xueqi Chen, Xinran Ni, Yu Zhang, Bei Zhu, Qun Zhang, Weihong Zhao

ABSTRACT Objectives Kidney function declines with aging, leading to a high prevalence of age‐related disease. Concurrently, the increasing prevalence of overweight and obesity may influence age‐related kidney changes. This study aims to clarify the relationship between body mass index (BMI) and kidney function in the Chinese population, with a focus on sex differences. Methods We conducted a retrospective cross‐sectional study involving 343,040 Chinese adults, stratified by sex and age. Glomerular filtration rate ( …

13.08.2026journal-article

Neuroscience Insights: Advances in Brain Studies

Bipolar Disorder in Older Adults: Clinical Presentation, Challenges, and Management Strategy

Michel Bourin

Bipolar disorder (BD) in older adults is a signifi cant yet under-recognized mental health concern. The clinical presentation in this population often diff ers from younger individuals, with increased cognitive impairment, comorbid medical conditions, and heightened sensitivity to medications. Accurate diagnosis is frequently complicated by overlapping symptoms with neurodegenerative disorders and age-related mood changes. This review examines epidemiology, clinical features, diagnostic challenges, and treatment st …