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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Paracapillaria philippinensis Infection in India: A Report of Four Cases

Ashis Kumar Choudhury, John Titus George, Nicholas Vijay Rao, Amit Kumar Dutta, Dipti Masih, Samuel George Hansdak, Ravikar Ralph, Sitara Swarna Rao Ajjampur

ABSTRACT. Capillaria philippinensis (recently renamed Paracapillaria philippinensis [ P. philippinensis ]) is a nematode infection endemic to Southeast Asia and Egypt and is rarely reported in India. This disease can be fatal if it is not diagnosed early and treated appropriately. Four cases of P. philippinensis infection identified over a decade from a single center in India are reported. All patients presented with diarrhea and reported symptoms such as abdominal pain, vomiting, and pedal edema, suggesting malabs …

02.09.2026journal-article

Frontiers in Nutrition

Flavonoids: biological activities, nutritional and immunological aspects, therapeutic potential, food applications, and human health benefits—A comprehensive review

Mohamed T. El-Saadony, Ahmed M. Saad, Mohamed A. Fahmy, Dina Mostafa Mohammed, Dina Khodeer, Esmael M. Alyami, Samar Sami Alkafaas, Mthokozisi Dladla, Soumya Ghosh, Mohammad A. A. Al-Najjar, Synan F. AbuQamar, Khaled A. El-Tarabily

The global burden of infectious and non-communicable diseases presents a critical challenge, highlighting the urgent need for novel, safe, and effective therapies. Bioactive compounds from medicinal plants, especially flavonoids, offer a promising resource for drug discovery due to their diverse and potent pharmacological effects documented in preclinical studies. This comprehensive review summarizes current knowledge of flavonoids, including their classification into 14 main groups and their production via biosynt …

02.09.2026journal-article

JAMA Surgery

Blood or Crystalloids for Hemorrhagic Shock—Response to the Agency for Healthcare Research and Quality

Julia R. Coleman, Reynold Henry, Nakul Raykar, John B. Holcomb

This Viewpoint evaluates the Agency for Healthcare Research and Quality report on prehospital blood transfusion and fluid interventions for hemorrhagic shock and argues that its claims of scientific equipoise stem from methodologic challenges instead of clinical equivalence of blood transfusion and crystalloid therapy.

02.09.2026journal-article

Journal of Functional Biomaterials

Data-Driven Development of Biomedical Hydrogels for Controlled Drug Delivery: Clinical Applications and Emerging Machine-Learning Approaches

Elham Eskandarnia, Ayah Binrajab, Adnan Alsaei, Fatema Rahimi, Nasser Alahmed, Ahmad Zarwi, G. Roshan Deen

Hydrogels are hydrated three-dimensional polymeric networks with biomedical potential because they can encapsulate therapeutic agents and provide localised, sustained, or stimulus-responsive drug delivery. Their performance is determined by interacting variables, including polymer composition, synthesis route, crosslinking chemistry, drug loading, swelling, degradation, and the biological microenvironment. This multidimensional design space often makes hydrogel development slow and dependent on trial-and-error expe …

02.09.2026journal-article

Pathogens

Partial Oral Antibiotic Therapy for Infective Endocarditis: A Practical Review of Current Evidence and Guidelines

Thomas Roland, Jean Cyr Yombi

Infective endocarditis (IE) is associated with an in-hospital mortality rate of 15–30%. Standard treatment requires 2 to 6 weeks of intravenous (IV) antibiotic therapy, resulting in prolonged hospitalization with its attendant risks, including catheter-related complications, increased length of stay, and cost. This review summarizes the current evidence, eligibility criteria, antibiotic regimen selection, and practical aspects of partial oral antibiotic therapy (POAT) for IE. Oral treatment is already recommended f …

02.09.2026journal-article

Medinformatics

An Adaptive Dual-Loop Artificial Intelligence Framework for Integrated Disease Surveillance and Health Workforce Learning in Low-Resource Health Systems

Kenneth Goga Riany, Agnes Linus Muthoni, Marcellah Eucabeth Onsomu, Pauldy C. J. Otermans, Dev Aditya

Background: In many low-resource health systems, disease surveillance and workforce training run on separate rails, so outbreaks are caught late, and frontline capacity stays thin. Most artificial intelligence (AI) tools pick one side or the other; almost none couple them. Methods: We built and tested an Adaptive Dual-Loop AI Framework. One loop, for epidemiological intelligence, handles multi-source ingestion, anomaly detection, and time series forecasting; the other, for workforce learning, runs a conversational …

02.09.2026journal-article

Smart Materials and Structures

Direct ink writing of flexible strain gauges for IoT-enabled structural health and usage monitoring of aerospace composites

Marilyne Philibert, Yuhang Pan, Ferri M.H Aliabadi, Zahra Sharif Khodaei

Abstract Structural health and usage monitoring of aerospace structures requires scalable, lightweight, and minimally intrusive sensing solutions capable of supporting real-time digital twin frameworks for individual aircraft life management. This work presents the development and characterization of flexible printed strain gauges as a core sensing component of the IoT sensing skin developed within the H2020 AVATAR project, dedicated to developing a digital twin framework for real-time health and usage monitoring o …

02.09.2026journal-article

Current Opinion in Clinical Nutrition & Metabolic Care

Iron deficiency during pregnancy and lactation

Laura Wasserfallen, Diego Moretti

Purpose of review Iron deficiency persists as the most common nutritional deficiency worldwide and is highly prevalent among women of reproductive age. Pregnancy substantially raises iron requirements, increasing the risk of complications for mother and newborn particularly in low-income and middle-income countries. We summarize current evidence on the determinants, physiological adaptations, diagnostic thresholds, and management of iron deficiency during pregnancy and lactation, focusing on recent developments. Re …

02.09.2026journal-article

The Clinical Teacher

Professional Identity Formation in the Transition From Undergraduate to Postgraduate Medical Education: A Scoping Review

Juliana Sá, Ana L. Da Silva, Pia Strand, Simon Kitto

ABSTRACT Background The transition from undergraduate to postgraduate medical education is a crucial phase of professional development, requiring trainees to assume greater clinical responsibility and adapt to new social norms. This transition influences professional identity formation (PIF), which is important for safe practice, well‐being and resilience. We conducted a scoping review to map studies of PIF during this transition and synthesise the key findings of this body of literature. Methods We searched five d …

02.09.2026journal-article

Journal of the American Society of Nephrology

ASN Kidney Health Guidance on the Cardiovascular-Kidney-Metabolic Syndrome

Nisha Bansal, Petter Bjornstad, Adam P. Bress, Tara I. Chang, Xingxing Cheng, Michelle M. Estrella, Alan S. Go, Amy K. Mottl, Sankar D. Navaneethan, Brendon L. Neuen, Brian S. Rifkin, Kim Zuber, Alexander R. Chang, on behalf of the ASN Kidney Health Guidance Workgroup on the Cardiovascular-Kidney-Metabolic Syndrome

Key Points The cardiovascular-kidney-metabolic (CKM) syndrome framework has important implications in the care of people with kidney diseases. Cardiovascular screening is important in people with kidney diseases, but the approach may differ in this high-risk population. Multiple pharmacotherapies for CKM syndrome offer significant cardiovascular and kidney benefits. Cardiovascular-kidney-metabolic (CKM) syndrome highlights the interconnected nature of cardiovascular disease, CKD, and metabolic dysfunction and under …

02.09.2026journal-article

Siberian Journal of Clinical and Experimental Medicine

The impact of intraoperative epiaortic scanning of the ascending aorta on the tactics and outcomes of coronary artery bypass grafting (literature review)

S. L. Andreev, Yu. Yu. Vechersky, V. V. Zatolokin, B. N. Kozlov

This review evaluates the use of intraoperative epiaortic scanning (IES) of the ascending aorta in coronary artery bypass grafting. The diagnostic advantages of IES 3 over traditional palpation and transesophageal echocardiography are discussed, allowing for the detection of atherosclerotic plaques, including mobile and ulcerated ones. Clinical trial data are presented, demonstrating that the use of IES leads to a change in surgical tactics in 5–15% of cases (avoidance of aortic manipulation, use of contactless dev …

02.09.2026journal-article

Journal of Psychedelic Studies

Classic psychedelic medicines for adolescent refractory mental health disease

Aly Shah Aziz

Abstract Adolescent refractory mental health disorders are rising globally, contributing to long-term morbidity and substantial societal burden. Conventional psychotropic medications and psychotherapeutic approaches sometimes fail to provide adequate relief, necessitating an interest in novel investigational interventions. Classic psychedelic compounds—Psilocybin, Lysergic Acid Diethylamide (LSD-25), and Dimethyltriptamine (DMT)—administered within Psychedelic Assisted Therapy (PAT) frameworks have shown strong eff …

02.09.2026journal-article

Dental Nursing

A valuable position

Tripat Mahajan

Tripat Mahajan discusses the role of the dental nurse in mouth cancer awareness and education.

02.09.2026journal-article

Anti-Cancer Agents in Medicinal Chemistry

In Silico Evaluation of Annonaceous Acetogenins as Potential HER2 and MELK Inhibitors for Targeted Cancer Therapy

Amisha Garg, Manasi Mishra

Introduction: Targeted cancer therapy focuses on inhibiting specific molecular pathways that drive tumor growth and survival. In this study, computational methods were employed to identify potential acetogenin- based inhibitors of two key anti-apoptotic proteins, HER2 and MELK. Given their crucial involvement in cancer pathogenesis, HER2 and MELK have emerged as significant molecular targets for the development of effective cancer therapies. Acetogenins, a class of bioactive compounds exclusive to the Annonaceae fa …

02.09.2026journal-article

Journal of Laparoendoscopic & Advanced Surgical Techniques

Clinical Outcomes of Magnesium-Based Balloon-Expandable Biodegradable Stenting for Benign Biliary Strictures: A Single-Center Retrospective Cohort Study

Mariano Eduardo Giménez, Chiara Innocenzi, Ignacio Corteggiano, Juliana Maria Racedo, Lucas Fehlauer, Samantha Robert, Pablo Acquafresca, Eduardo Houghton, Mariano Palermo

Background: Benign biliary strictures, most commonly anastomotic after hepaticojejunostomy or related to bile duct injury, are conventionally managed with balloon dilation, multiple plastic stents, or covered metal stents, all of which typically require repeated procedures. Magnesium-based balloon-expandable biodegradable stents (UNITY-B) have been proposed as a single-step alternative, but dedicated cohort data are limited. Methods: We retrospectively reviewed 22 consecutive UNITY-B stent-placement procedures perf …

02.09.2026journal-article

Healthcare

Digital Health Revolution in Saudi Arabia: A Narrative Review of Healthcare Transformation

Mahmoud Abdel Hameed Shahin

Digital transformation (DT) is a strategic priority for healthcare systems seeking to improve the quality of care, patient safety, and operational efficiency. In Saudi Arabia, DT is central to Vision 2030; however, evidence regarding its effects on healthcare quality and safety remains dispersed across technologies and healthcare settings. This narrative review aimed to examine the impact of digital transformation on healthcare quality and patient safety in Saudi Arabia and to identify the principal implementation …

02.09.2026journal-article

Evidence-Based Chinese Medicine and Technology Assessment

How can traditional Chinese medicine trials achieve global credibility

Ying Wang, Gordon Guyatt

Abstract Traditional Chinese medicine (TCM) needs credible evidence that meets international evidence-based medicine standards to achieve global credibility and acceptance. A fundamental and crucial task is to conduct high-quality randomized controlled trials (RCTs). To achieve global credibility, TCM RCTs should meet universal standards of scientific rigor, such as addressing clinically important questions, achieving sufficient sample size and minimizing risk of bias, and enhance generalizability through appropria …

02.09.2026journal-article

Journal of Nursing, Midwifery and Allied Health Sciences

Measurement Equivalence between Pidgin English and Igbo Versions of the Birth Satisfaction Scale–Revised among Postpartum Women in Owerri, Nigeria

Anne Chidinma Nwogu, Ayishetu Musa-Maliki, Yarhere Iroro, Joy Chiamaka Samuel, Josephine Nonye Amadi

Birth satisfaction is an indicator of the quality of intrapartum care, yet evidence on measurement equivalence of birth satisfaction instruments across Nigerian languages remains limited. In multilingual settings such as Nigeria, where Nigerian Pidgin is widely used alongside indigenous languages such as Igbo, establishing cross-language equivalence of patient-reported outcome measures is essential to ensure valid comparison of maternal birth experiences. This study assessed measurement equivalence between the Nige …

02.09.2026journal-article

Healthcare

Knowledge and Self-Reported Clinical Approaches Regarding Medication-Related Osteonecrosis of the Jaw Among Final-Year Dental Students, General Dentists, and Specialist Dentists: An Exploratory Cross-Sectional Study

İsmail Çapar, Çiğdem Şeker

Background/Objectives: Medication-related osteonecrosis of the jaw (MRONJ) must be recognized promptly by dental professionals at every career stage, yet whether this recognition differs across professional levels remains unclear. This study compared final-year dental students, general dentists, and specialist dentists in terms of their awareness, pharmacological knowledge, and self-reported clinical approaches to MRONJ. Methods: This cross-sectional, exploratory study used a 25-item online questionnaire administer …

02.09.2026journal-article

Journal of Crop Health

Atmospheric Dynamics and Diversity of Alternaria and Fusarium in a Common Wheat (Triticum aestivum L.) Crop in NW Spain

Kenia C. Sánchez Espinosa, Esperanza Duarte-Escalante, María Fernández-González, María del Rocío Reyes-Montes, Francisco Javier Rodríguez-Rajo

Abstract This study investigated the diversity of Alternaria and Fusarium species in atmospheric aerosols and plant tissue in a common wheat crop in NW Spain. The relationship between atmospheric fungal spore concentrations and weather conditions was analysed. To this end, non-viable and viable aerobiological monitoring methodologies were combined with isolates from plants showing symptoms of fungal infection. The isolates were identified by morphological characterisation and phylogenetic analysis of the 1‑alpha el …

02.09.2026journal-article

Regional Anesthesia & Pain Medicine

When gastric point-of-care ultrasound is indeterminate: an educational review and suggested reporting framework

Stephen C Haskins, Cristian Arzola, Yuriy Bronshteyn, Hari Kalagara, David Hardman, Oliver Panzer, Marissa M Weber, Eric Heinz, Jan Boublik, Javier Cubillos, Nadia Hernandez, Joshua Zimmerman, Anahi Perlas

Gastric point-of-care ultrasound (POCUS) is increasingly used to support aspiration-risk assessment when fasting history, comorbidities, medication exposure, or procedural urgency make clinical assessment uncertain. Its value depends on more than identifying gastric contents when images are clear. A useful examination must be attempted, completed, interpreted, and connected to a safe clinical decision. This article uses a focused secondary analysis of the 65 studies included in the original narrative review of gast …

02.09.2026journal-article

European Journal of Nutrition & Food Safety

Next-generation Probiotics for Human Health: A Critical Narrative Review of Mechanisms, Clinical Translation, Safety and Precision Microbiome Therapeutics

Sandhya Dhyani, Himani Belwal, Neetu Dobhal

The term next-generation probiotic (NGP) is increasingly used for health-associated gut commensals and rationally engineered microorganisms developed from microbiome science rather than from the historical food-fermentation route that produced most conventional probiotics. This expansion has created a translational opportunity, but also a recurrent evidential problem: taxonomic association, mechanistic plausibility, preclinical efficacy, human safety and clinical benefit are often treated as if they formed a single …

02.09.2026journal-article

BMC Medical Imaging

Automated whole-brain MRI segmentation combined with clinical scores for the diagnosis of sepsis-associated encephalopathy: a case-control study

Shasha Shao, Yanyan Liu, Jiale Yang, Daixing Zhou, Chengdong Peng, Dong Liu, Junshuai Wang, Jun Feng

Abstract Background Sepsis-associated encephalopathy (SAE) is a serious complication of sepsis that can lead to high mortality and poor neurological outcomes. Current diagnostic methods, whether based on clinical scores or brain images, remain inaccurate. We aimed to formulate a multimodal model that incorporated three-dimensional (3D) magnetic resonance imaging (MRI) neuroanatomical characteristics with clinical scores to improve SAE detection. Methods In this retrospective case-control study, 35 healthy controls …