Analyzing Mortality Trends in a UK Pediatric Critical Care Long-Stay Patient Cohort

Vollständiger Abstract

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Objectives: Long-stay patients in PICU are at-risk of higher mortality. The long-stay PICU population is growing larger. Identification of indicators of adverse outcomes in this cohort may provide opportunities for timely counselling and support. We aim to analyse the factors associated with higher mortality in the long-stay PICU patient cohort. Methods: Retrospective single centre study of long-stay PICU admissions defined as a PICU length of stay of at least 28 days during a three-year study period (1st April 2017 to 31st March 2020). Outcomes analysed included in-PICU mortality, and mortality within 12 months of PICU discharge. Variables analysed for association with outcomes, included primary diagnostic category, number and nature of additional comorbidities, long-term ventilation pathway etc. Results: During a three-year period, there were 2848 unique individual patient admissions to the PICU. 165 children had 172 long-stay admissions. The overall in-PICU mortality of long-stay patients was 30.2% compared to 6.4% (p