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Dystonia 3×3: A Training Guideline for Beginners in Botulinum Neurotoxin Treatment of Cervical Dystonia

Sebastian Paus, Andreas Funke, Jürgen Hamacher, Bernhard Haslinger, Jan Heckelmann, Chi Wang Ip, Wolfgang H. Jost, Anatol Kivi, Stephan Klebe, John-Ih Lee, Ebba Lohmann, Frederic Mack, Axel Schramm, Andrea Stenner, Pawel Tacik, Uwe Walter, David T. Weise

Toxins · 2026

Vollständiger Abstract

Worum geht es in dieser Arbeit?

Cervical dystonia (CD) is a hyperkinetic movement disorder characterized by involuntary muscle contractions leading to abnormal postures of the head and neck. The injection of botulinum neurotoxin type A (BoNT-A) into the muscles involved is the treatment of choice for CD. BoNT-A therapy of CD requires appropriate training, which has not been standardized in Germany. To address the key challenges in BoNT-A education, an expert panel developed a simplified step-by-step treatment guideline for beginners, adapted from the established Col-Cap-Concept (“Dystonia 3×3”). Based on expert consensus, recommendations were developed for the core clinical elements of BoNT-A treatment in CD—recognition of the movement pattern, identification of target muscles, development of an injection plan, ultrasound-guided injection, and dosing, taking into account the target audience of the guideline. As such, Dystonia 3×3 provides a user-friendly beginner’s guidebook, enhancing accessibility and standardization of CD treatment training. Further research is required to evaluate its clinical efficacy and suitability for training.

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Autor:innen
Sebastian Paus, Andreas Funke, Jürgen Hamacher, Bernhard Haslinger, Jan Heckelmann, Chi Wang Ip, Wolfgang H. Jost, Anatol Kivi, Stephan Klebe, John-Ih Lee, Ebba Lohmann, Frederic Mack, Axel Schramm, Andrea Stenner, Pawel Tacik, Uwe Walter, David T. Weise
Quelle
Toxins
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
2072-6651
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Sebastian Paus, Andreas Funke, Jürgen Hamacher, Bernhard Haslinger, Jan Heckelmann, Chi Wang Ip, Wolfgang H. Jost, Anatol Kivi, Stephan Klebe, John-Ih Lee, Ebba Lohmann, Frederic Mack, Axel Schramm, Andrea Stenner, Pawel Tacik, Uwe Walter, David T. Weise (2026). Dystonia 3×3: A Training Guideline for Beginners in Botulinum Neurotoxin Treatment of Cervical Dystonia. Toxins. https://doi.org/10.3390/toxins18090378
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