Day-7 caloric intake as an early dynamic prognostic marker for subsequent mortality in older patients with dysphagia: a landmark cohort analysis

Vollständiger Abstract

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Background Early nutritional status may influence prognosis in older adults with dysphagia receiving artificial nutrition. However, the predictive value of caloric intake shortly after initiation of enteral or parenteral nutrition remains unclear. This study aimed to investigate the association between day-7 caloric intake and subsequent all-cause mortality in older Japanese patients with dysphagia and assess its potential as an early dynamic prognostic marker. Methods We conducted a day-7 landmark cohort analysis of 246 older adults who survived beyond 7 days after initiation of percutaneous endoscopic gastrostomy (PEG) or total parenteral nutrition (TPN). Day-7 caloric intake was analyzed both as a continuous variable (per 100 kcal/day) and categorically (