Vollständiger Abstract
Worum geht es in dieser Arbeit?
The oral-systemic connection, salivary microbiome, and healthy longevity are increasingly recognized as biologically interconnected. This review summarizes lifespan changes in the salivary microbiome, its links to age-related systemic diseases, and recent progress in salivary MicroAge modeling. It further highlights advances in data preprocessing, feature engineering, and artificial intelligence-based prediction, while emphasizing the importance of standardization, generalizability, and biological interpretability for clinical translation. Overall, salivary MicroAge may provide a noninvasive and interpretable framework for biological aging assessment and healthier aging.
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Tongjun Guo, Yixuan Chen, Yuehan Yu, Yilin Shao, Cong Wang, Xue Li, Haoyu Zhang, Chao Xu, Yoo Cheung, Feng Chen, Tiansong Xu, Xiuhua Li, Chenggang Duan
- Quelle
- Frontiers in Microbiology
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 1664-302X
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Zitierfähiger Nachweis
Tongjun Guo, Yixuan Chen, Yuehan Yu, Yilin Shao, Cong Wang, Xue Li, Haoyu Zhang, Chao Xu, Yoo Cheung, Feng Chen, Tiansong Xu, Xiuhua Li, Chenggang Duan (2026). Clinical translation of salivary MicroAge for understanding the oral-systemic connection in healthy longevity. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2026.1903972
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