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Urolithin A-induced mitophagy: a mitochondrial therapeutic axis for decelerating musculoskeletal aging and modulating knee osteoarthritis pain

Aavrati Rastogi, Roop B. Kalia, Mukesh Bairwa

International Journal Of Community Medicine And Public Health · 2026

Vollständiger Abstract

Worum geht es in dieser Arbeit?

Knee osteoarthritis (OA) is a disease characterized by cellular energy dysregulation, in which structural joint deterioration and chronic pain are caused by mitochondrial dysfunction. OA is now recognized as a multifactorial condition caused by disturbed cellular homeostasis, metabolic imbalance, and typical biological processes of aging, notably mitochondrial dysfunction. However, it was once thought to be caused by mechanical wear and cartilage degradation

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Publikationsdaten

Autor:innen
Aavrati Rastogi, Roop B. Kalia, Mukesh Bairwa
Quelle
International Journal Of Community Medicine And Public Health
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
2394-6040, 2394-6032
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Zitierfähiger Nachweis

Aavrati Rastogi, Roop B. Kalia, Mukesh Bairwa (2026). Urolithin A-induced mitophagy: a mitochondrial therapeutic axis for decelerating musculoskeletal aging and modulating knee osteoarthritis pain. International Journal Of Community Medicine And Public Health. https://doi.org/10.18203/2394-6040.ijcmph20263245
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