Gut-ocular axis: An emerging strategy to treat ocular diseases

Vollständiger Abstract

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The gut-eye axis is a bidirectional communication pathway linking gut microbiota to ocular health, where a dysbiotic gut can contribute to eye diseases like age related macular degeneration, diabetic retinopathy, uveitis, and dry eyes; even ocular conditions can also influence the gut. This gut - ocular axis offers new therapeutic targets using probiotics, prebiotics, dietary modification, or novel methods like fecal microbiota transplantation to improve eye health. This review also discusses future research prospects in the gut-eye axis, while addressing a research gap in the existing literature.