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Sex hormones and menopause hormone therapy predict muscle strength across the lifespan

Rachel N. Logue Cook, Adina F. Turcu, Carrie A. Karvonen-Gutierrez, Sandra K. Hunter

Journal of Applied Physiology · 2026

Vollständiger Abstract

Worum geht es in dieser Arbeit?

We demonstrate that sex hormone concentrations are associated with age-related declines in muscle strength across the lifespan. Bioavailable testosterone was a predictor of handgrip strength, whereas total testosterone was not in both males and females, and estradiol was a strong predictor of strength in females during midlife and older age. Furthermore, menopause hormone therapy may have beneficial effects on strength maintenance in older females, particularly in sedentary females.

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Publikationsdaten

Autor:innen
Rachel N. Logue Cook, Adina F. Turcu, Carrie A. Karvonen-Gutierrez, Sandra K. Hunter
Quelle
Journal of Applied Physiology
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
8750-7587, 1522-1601
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Zitierfähiger Nachweis

Rachel N. Logue Cook, Adina F. Turcu, Carrie A. Karvonen-Gutierrez, Sandra K. Hunter (2026). Sex hormones and menopause hormone therapy predict muscle strength across the lifespan. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00366.2026
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