Vollständiger Abstract
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Objectives Cancer cachexia (CC) reduces treatment efficacy, quality of life and survival. However, few contemporary data quantify its prevalence or impact on death. This study assessed cachexia prevalence in advanced cancer using multiple diagnostic frameworks and explored its role in cancer-related mortality. Methods A retrospective analysis was conducted of all deaths over 3 years (August 2020 to August 2023) at a specialist palliative care unit. Using clinical, biochemical and CT body composition data, four definitions of CC (Evans et al , Fearon et al , Global Leadership Initiative on Malnutrition (GLIM) and the modified Glasgow Prognostic Score) were applied. A cachexia-related death was defined as one of global deterioration, infection, thrombo-embolic event or cardiac failure. Paired within-patient analysis compared measurements 30–90 days versus
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Michael S Yule, Flora Flinn, Elizabeth Mitchell, Jonathan Grey, Ratish Balagangatharan, Christian Montgomery, Leo R Brown, Duncan J F Brown, Barry J A Laird, Richard J E Skipworth
- Quelle
- BMJ Supportive & Palliative Care
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 2045-435X, 2045-4368
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Zitierfähiger Nachweis
Michael S Yule, Flora Flinn, Elizabeth Mitchell, Jonathan Grey, Ratish Balagangatharan, Christian Montgomery, Leo R Brown, Duncan J F Brown, Barry J A Laird, Richard J E Skipworth (2026). Prevalence of cachexia in advanced cancer and its impact on death: a retrospective analysis. BMJ Supportive & Palliative Care. https://doi.org/10.1136/spcare-2026-006305