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Oral Cyanocobalamin Treatment in Infants Under 1 Year With Nutritional Vitamin B12 Deficiency: A Retrospective Comparison of 500 and 1000 µg Dose Regimens

Gökçe P. Reis İskenderoğlu, Erol Erduran, Nilgün Eroğlu, Ayşenur Bahadır

Journal of Pediatric Hematology/Oncology · 2026

Vollständiger Abstract

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Background: Vitamin B12 deficiency is a significant health problem in infancy, particularly in developing countries. Oral treatment has emerged as an alternative to intramuscular therapy, but optimal dosing in infants remains unclear. Methods: This retrospective study included 93 infants aged 1 to 12 months diagnosed with nutritional vitamin B12 deficiency. Patients received either 500 or 1000 µg oral cyanocobalamin. Laboratory parameters were evaluated at baseline, 2 months, and 4 months. Results: Both treatment groups demonstrated significant increases in serum vitamin B12 levels and decreases in homocysteine levels ( P

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Publikationsdaten

Autor:innen
Gökçe P. Reis İskenderoğlu, Erol Erduran, Nilgün Eroğlu, Ayşenur Bahadır
Quelle
Journal of Pediatric Hematology/Oncology
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
1077-4114, 1536-3678
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Zitierfähiger Nachweis

Gökçe P. Reis İskenderoğlu, Erol Erduran, Nilgün Eroğlu, Ayşenur Bahadır (2026). Oral Cyanocobalamin Treatment in Infants Under 1 Year With Nutritional Vitamin B12 Deficiency: A Retrospective Comparison of 500 and 1000 µg Dose Regimens. Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/mph.0000000000003251
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