Vollständiger Abstract
Worum geht es in dieser Arbeit?
Abstract Infrequent standard-of-care (SOC) testing for respiratory syncytial virus (RSV) in adults with acute respiratory illness (ARI) contributes to underestimated disease burden. We compared RSV prevalence and RSV vaccine effectiveness (VE) among 14,044 adults ≥60 years with ARI ED/hospital admissions receiving SOC RSV testing versus those with SOC or salvaged respiratory specimen RSV testing. RSV was identified in 139 (0.99%) specimens by SOC testing alone versus 483 (3.44%) via SOC combined with salvage testing. Precision of VE against RSV-related ARI ED/hospital admissions improved substantially with inclusion of salvage testing compared to SOC testing alone (92% [67%- 98%] vs 90% [29%- 99%]).
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Bradley K Ackerson, Brandon Chia, Negar Aliabadi, Gabriella Goodwin, Jeff Slezak, Vennis Hong, Qing Liu, Sally Shaw, Sabrina Welsh, Julie A Stern, Banshri Kapadia, Brigitte C Spence, Joseph A Lewnard, Gregg Davis, Evan J Zasowski, Michael Aragones, Ashley Miller, Michael Dutro, Erica Chilson, Elisa Gonzalez, Robin Hubler, Luis Jodar, Bradford D Gessner, Elizabeth Begier, Sara Y Tartof
- Quelle
- Open Forum Infectious Diseases
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 2328-8957
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Zitierfähiger Nachweis
Bradley K Ackerson, Brandon Chia, Negar Aliabadi, Gabriella Goodwin, Jeff Slezak, Vennis Hong, Qing Liu, Sally Shaw, Sabrina Welsh, Julie A Stern, Banshri Kapadia, Brigitte C Spence, Joseph A Lewnard, Gregg Davis, Evan J Zasowski, Michael Aragones, Ashley Miller, Michael Dutro, Erica Chilson, Elisa Gonzalez, Robin Hubler, Luis Jodar, Bradford D Gessner, Elizabeth Begier, Sara Y Tartof (2026). The Impact of Respiratory Syncytial Virus Undertesting on Estimates of Disease Burden and Vaccine Effectiveness in a Large Integrated Healthcare System. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofag572
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