Vollständiger Abstract
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Abstract Background Strategies that seek to provide timely and effective therapy for febrile neutropenia (FN) in children with cancer or hematopoietic cell therapy (HCT) are threatened by increasing rates of antimicrobial resistance (AR). At our institution clinically stable patients with FN are treated with cefepime but this carbapenem-sparing strategy results in delays in the time to effective antimicrobial therapy and poorer clinical outcomes in patients with Gram-negative bloodstream infection (GNBSI) caused by cefepime nonsusceptible (CN) bacteria. Identification of risk factors for CN may allow providers to individualize treatment and improve outcomes. Methods This retrospective single-center study included patients
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Alexander Pruett, Jose Ferrolino, Ronald Dallas, Yilun Sun, Elisabeth Adderson
- Quelle
- Journal of the Pediatric Infectious Diseases Society
- Publikation
- 2026-01-01
- Band / Ausgabe
- Nicht angegeben
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 2048-7207
- Zitationen
- 0 laut Crossref
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Zitierfähiger Nachweis
Alexander Pruett, Jose Ferrolino, Ronald Dallas, Yilun Sun, Elisabeth Adderson (2026). Risk factors for Cefepime Resistance in Bacteria Causing Gram-negative Bloodstream Infections in a Children’s Cancer Center. Journal of the Pediatric Infectious Diseases Society. https://doi.org/10.1093/jpids/piag070/piag070.079
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