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Host RNA-binding proteins as broad-spectrum targets for antiviral therapy

Sagnik Biswas

npj Viruses · 2026

Vollständiger Abstract

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Abstract RNA-binding proteins (RBPs) regulate key host processes and facilitate viral replication. Certain antiviral RBPs limit infection and trigger immune responses. Targeting these proteins could yield broad-spectrum antiviral activity with a lower risk of resistance. Nonetheless, translating this approach into clinical use requires balancing antiviral activity with the preservation of essential host functions. This review explores current RBP-directed antivirals and considers key challenges and future research directions.

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Publikationsdaten

Autor:innen
Sagnik Biswas
Quelle
npj Viruses
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
2948-1767
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Zitierfähiger Nachweis

Sagnik Biswas (2026). Host RNA-binding proteins as broad-spectrum targets for antiviral therapy. npj Viruses. https://doi.org/10.1038/s44298-026-00234-0
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