Academia Medicine and Health

26.08.2026

Permeability to value in healthcare innovation procurements: a framework for design and assessment

Introduction: To address emerging health system needs that existing solutions fail to meet, public administrations must foster the development, implementation, adoption, and scaling of new goods and services. Innovation procurement allows the public sector to act as a promoter of …

14.08.2026

Intraoperative indocyanine green imaging for phlebosclerotic colitis with small bowel obstruction

Introduction: Phlebosclerotic colitis is a rare form of ischaemic colitis characterised by calcification and sclerosis of the mesenteric veins. It has been reported predominantly in Asian populations, although cases have also been described elsewhere. Clinical presentation is var …

29.07.2026

Mortality predictors of Clostridioides difficile infection in inflammatory bowel disease

Introduction: Inflammatory bowel disease (IBD) is characterized by chronic relapsing and remitting inflammation of the gastrointestinal tract. Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacillus. C. difficile infection (CDI) is the leading cause of coli …

21.07.2026

Need for guidance: a multidisciplinary survey on surgical emergencies in peritoneal surface malignancies

Introduction: Advances in systemic chemotherapy, cytoreductive surgery, and intraperitoneal treatment have improved long-term outcomes in peritoneal carcinomatosis (PC), yet acute complications such as obstruction, perforation, and strangulation remain poorly standardized in thei …

01.07.2026

Intravenous artesunate for imported malaria in pregnancy: two case reports

Introduction: Pregnant women have historically been underrepresented in clinical trials, resulting in limited evidence regarding malaria management in this population. This knowledge gap is particularly evident for imported malaria cases occurring in non-endemic regions. Case pre …

24.06.2026

Frontiers of renal medicine: innovation, crosstalk, and sustainable restoration in chronic kidney disease

Chronic kidney disease (CKD) affects more than 850 million people worldwide, caused mostly by aging, diabetes, and hypertension. Current management remains focused on renal replacement therapies (RRT), such as dialysis and transplantation, with limited capacity for prevention or …

23.06.2026

The destruction of healthcare in armed conflict: policy implications and accountability

This Perspective examines how the destruction of healthcare systems in armed conflict produces enduring public health harm and broad human insecurity. Drawing on social medicine, sociological theory, governance scholarship, and field observations from Afghanistan, it argues that …

15.06.2026

Adapted arm cycle ergometer training in COPD: randomized functional outcomes

Introduction: Patients with chronic obstructive pulmonary disease (COPD) frequently present peripheral muscle dysfunction, especially during unsupported upper limb activities, contributing to dyspnea, reduced exercise tolerance, and limitations in activities of daily living. Mate …

13.05.2026

Characterizing sleep disturbance phenotypes in long COVID: an EHR-based study from a safety-net hospital

Introduction: Sleep disturbances, including insomnia and hypersomnia, are among the most common and disabling symptoms of post-acute sequelae of SARS-CoV-2 infection (PASC), yet their pathophysiologies are incompletely understood. This study aimed to characterize sleep disturbanc …

29.04.2026

“A new type of dementia—called seizures”: temporal lobe epilepsy presenting as episodic neuropsychiatric symptoms

Introduction: Older adults frequently present with episodic mood changes and fluctuating memory lapses, which can be mistaken for depression or early neurodegenerative disease. Astute clinicians know that through careful history, physical, and appropriate test examinations, the d …

28.04.2026

Medicine and health: a necessary reunion

24.04.2026

Iron metabolism and genetic modifiers in thalassemia and sickle cell anemia

Iron metabolism plays a crucial role in the management of hemoglobinopathies, particularly in conditions such as β-thalassemia and sickle cell disease (SCD). This paper reviews briefly the present knowledge of iron overload in patients with transfusion-dependent thalassemia (TDT) …

24.04.2026

Focal cortical dysplasia and Bartter syndrome with refractory epilepsy and neurodevelopmental delay: a rare co-occurrence

Introduction: Focal cortical dysplasia (FCD) is a known cause of early-onset drug-resistant epilepsy (DRE). Bartter syndrome (BS) is a rare renal tubular disorder characterized by hypokalemia, hypomagnesemia, and metabolic alkalosis. Structural brain malformations are not conside …

15.04.2026 · 1 Zitationen

Demographic-specific TyG and TyG-BMI thresholds improve insulin resistance and mortality risk

Introduction: Insulin resistance (IR) is a key contributor to metabolic disorders and mortality. The triglyceride–glucose (TyG) and TyG–body mass index (TyG-BMI) indices are increasingly used as surrogate markers of IR. However, the influence of demographic factors, such as age, …

08.04.2026

The accuracy of an abbreviated echocardiographic protocol for the detection of congenital heart disease in newborns

Introduction: Although prenatal detection rates of congenital heart disease (CHD) have improved over time with modifications of scanning guidelines, in Australia, approximately 1/3 of infants with CHD are detected postnatally and delivered in centres without cardiac services. Ret …

01.04.2026

Relationship between peripheral muscle strength and functional mobility at extubation and ICU discharge in mechanically ventilated critically ill patients

Introduction: Muscle weakness acquired in the intensive care unit (ICU) (ICU-AW) is associated with worse clinical outcomes and prolonged functional recovery. Although handgrip strength (HS) and Perme mobility score (PE) are widely used, the relationship between peripheral streng …

05.03.2026

Value-based surgical care: barriers, facilitators and incentives. A meta-ethnographic synthesis

Introduction: Surgical specialties are increasingly being asked to transition from traditional volume-based fee-for-service models to value-based care, which prioritizes patient outcomes and cost-efficiency. Understanding the unique financial and operational challenges of value-b …

13.02.2026

Perceived impact of regular short-term medical missions: a qualitative study in Uganda

Introduction: While short-term medical missions (STMMs) are widely used to deliver humanitarian healthcare in low- and middle-income countries, existing research has largely focused on one-off interventions and has highlighted ongoing concerns related to sustainability, continuit …

13.02.2026

Armed conflict and cholera outbreaks: a narrative review of epidemiology, challenges, and responses

Background: Cholera remains a significant global public health threat, with its burden disproportionately affecting regions experiencing humanitarian crises. Armed conflict, through the disruption of infrastructure and governance, creates ideal conditions for cholera transmission …

03.02.2026

Assessment of knowledge of management of childhood diarrhoea among exclusively breastfeeding mothers in Oyo State, Nigeria

Background: Over the years, Oral rehydration solution [ORS] and zinc supplementation have proven to be simple and effective interventions for diarrhoea management. ORS usage ensures an estimated risk reduction of mortality due to childhood diarrhoea mortality by 93%, and zinc sup …

19.01.2026

Gravity-dependent blood pressure rise in essential hypertension: mechanism of orthostatic hypertension

Background: Orthostatic hypertension (oHTN)—a paradoxical increase in blood pressure upon standing—remains understudied despite its association with increased cardiovascular risk in individuals with essential hypertension. The role of low-pressure cardiopulmonary reflexes in medi …

09.01.2026

Clinical burden of dry eye disease in patients with ocular graft versus host disease

Background: Ocular graft-versus-host disease (oGVHD) is a frequent complication after hematopoietic stem cell transplant, with dry eye being the most common presentation. Patient experience with dry eye from oGVHD may negatively affect quality of life. The purpose of this study w …