Wissenschaftliches Journal · EZB
Hindawi Limited
Inhaltsverzeichnis
18.05.2026
Samson Olusola Adeboye, Victoria Olubunmi Olarewaju, Omolara Veronica Allen, Samuel Adeniyi Oyegbade, Bose Janet AdeboyeThe criticality of the first 1000 days of life in setting the stage for the colonization and development of infant gut microbiota cannot be negotiated. Multiple interactions going on within this period contribute to the composition and diversity of microbes found in this ecosyste …
20.08.2026
Doofan Bur, Kelechi Purity Ezennubia, Emmanuel Kennedy Ezika, Oluwabukunmi Ifedamola Rowaiye, Adekunle RowaiyeThe global escalation of multidrug‐resistant (MDR) bacteria necessitates alternative antimicrobial strategies beyond conventional antibiotics. Bacteriophage therapy has re‐emerged as a promising intervention, offering targeted bacterial killing with minimal disruption to host mic …
03.08.2026
Marcel Martínez-Porchas, Diana Medina-Félix, Cinthia Alejandra Olivas Bernal, Jesús Olivier Guirado-Flores, Francisco Vargas-Albores, Marcos Porchas-Quijada, Estefanía Garibay-ValdezThe microbiota–gut–brain axis (MGBA) is a dynamic bidirectional communication network that integrates microbial, neural, endocrine, and immune signals to regulate host physiology and behavior. This review synthesizes current evidence on the molecular mechanisms by which gut micro …
29.07.2026
Amelia H. Torster, Steven J. A. KimbleThe gut microbiome in Sauropsida—reptiles and wild birds—is vastly understudied. This lack of data and understanding creates an inefficiency in studies and conservation efforts. We address this through a collection of data from 64 published research papers. In this review, we pro …
18.08.2026
Sajjad Hassan QadeerThe gut microbiota of livestock is a metabolically active ecosystem that profoundly influences nutrient uptake, immune regulation and productive performance; its nutritional manipulation has emerged as a primary strategy for maintaining animal health in the postantibiotic era. A …
15.06.2026
Balasubramanian Chellammal Muthubharathi, Krishnaswamy BalamuruganInfectious diseases continue to pose a significant challenge to global health, particularly with the emergence of multidrug‐resistant pathogens. Understanding host–pathogen interactions (HPIs) is fundamental to uncovering mechanisms of infection, immunity, and adaptation. This na …
21.05.2026
Joha De Maayer, Pieter De Maayer, John Devar, Jasmin Patel, Palesa Ramashila, Geoffrey Candy, Ekene Emmanuel Nweke, Angela BotesPurpose The microbiome is increasingly recognised as a contributor to pancreatic ductal adenocarcinoma (PDAC) pathogenesis, presenting opportunities for biomarker discovery and therapeutic intervention. Characterising microbial signatures associated with PDAC could improve early …
07.07.2026
Hadda Lyzandra Austríaco Leite, Fernanda Ferreira LopesPeriodontopathogenic bacteria have been increasingly implicated in the prognosis of colorectal cancer. Among these microorganisms, Fusobacterium nucleatum has been frequently detected in tumor tissues and associated with unfavorable clinical outcomes. However, observational evide …
15.07.2026
Alfi Sophian, AbinawantoBackground and Aims Interactions between host noncoding RNAs (ncRNAs) and the tumor‐associated microbiome represent an emerging regulatory axis in cancer biology. Despite individual advances, a unified mechanistic framework integrating ncRNA biology, microbial oncology, and epitr …
06.05.2026 · 1 Zitationen
Mani Sebastian, S. Abhirami, D. S. Amrutha, R. Haritha, Maya G. Pillai, A. HelenAtherosclerosis is increasingly understood as a metabolically driven disease influenced by diet and lifestyle factors. Beyond traditional risk factors, the gut microbiota play a critical role in atherogenesis. Dietary patterns alter the gut microbiota to favor the synthesis of pr …
09.07.2026
Abongile Tolana, Xolani Mbongozi, Muambangu Jean Paul MilamboBackground Puerperal sepsis remains a major contributor to maternal morbidity and mortality, particularly in low‐ and middle‐income countries. The growing burden of antimicrobial resistance further complicates its management and threatens the effectiveness of empiric antibiotic t …
19.03.2026 · 1 Zitationen
N. V. Kanimozhi, S. Nagalakshmi, M. SukumarMetabolic dysfunction associated steatohepatitis (MASH) (formerly nonalcoholic steatohepatitis, NASH) is a progressive manifestation of metabolic dysfunction‐associated steatotic liver disease, strongly linked to oxidative stress and gut–liver axis dysregulation. Targeting microb …
13.04.2026 · 8 Zitationen
Mohammad Nazrul Islam Bhuiyan, Barun Kanti Saha, Mohammed Abdus Satter MiahThe convergence of artificial intelligence (AI) and microbiome science is reshaping strategies for modulating the gut microbiota to support healthy aging and precision nutrition. In this review, we synthesized recent advances in AI‐enabled tribiotic strategies—encompassing probio …
07.04.2026
Samson Adedeji Adejumo, Chioma Miracle Ojiako, Pritha Das, Felix Chukwuebuka Onyia, Mavis Nkem Okafor, Ifeanyi Ferdinand Chukwuma, Jarrad Hampton-Marcell, Angus Nnamdi OliProbiotics are emerging as promising alternative therapies with diverse health applications, particularly in enhancing immunity and combating infectious diseases. This scoping review synthesizes evidence on the immunomodulatory and antimicrobial effects of well‐characterized stra …
06.04.2026 · 1 Zitationen
Debabrata Dash, Raj Kumar KoiriChronic liver diseases (CLDs) are a heterogeneous group of disorders that involve progressive damage to the liver cells, leading to inflammation, metabolic disorders, and fibrosis. There is increasing evidence that abnormal iron metabolism is an important contributing factor in C …
11.04.2026
Kate R. Secombe, Ana R. da Silva Ferreira, Hanna L. Simpson, Mafalda Bispo, Andrea M. Stringer, Rachel J. Gibson, Wim J. E. Tissing, Hermie H. M. Harmsen, Joanne M. Bowen, Hannah R. WardillGastrointestinal mucositis (GI‐M) is a dose‐limiting complication of chemotherapy initiated by direct cytotoxic injury to the intestinal epithelium. It is then perpetuated by aberrant immune responses driven by the host and their microbiota. GI‐M presentation is heterogeneous, hy …
26.08.2026
Muhammad Lawal Jidda, Jafaru Muhammad Bunza, Halima Hussaini Salihu, Umar Asiya Imam, Muhammad Kabiru Dallatu, Ogunwale Kolawole Ayobami, Yusuf Habeb Demilola, Giwa Jamiah Ikeoluwa, Oladele Blessing Shina, Aliyu Maimuna Umar, Idris Safiyya AminuBackground Branched‐chain amino acids (BCAAs) are established biomarkers of insulin resistance. However, their relationship with gut microbiota composition, dietary patterns, and systemic inflammation in African populations with Type 2 diabetes mellitus (T2DM) remains unexplored. …
29.07.2026
Moses Ojo Oke, Oluwatoba Felix Owoyomi, Akeju Favour Omobade, Emmanuel Sunday OniHelicobacter pylori infection remains highly prevalent in low‐ and middle‐income countries and is influenced by demographic, clinical, and environmental factors. University students may be at increased risk due to shared living conditions and behavioral exposures. A cross‐section …
27.05.2026
Philip Boakye Bonsu, Kwadwo Fosu, Samuel Badu NyarkoThe complications that arise from pregnancy such as preterm birth (PTB), preeclampsia, and neonatal sepsis continue to pose significant threats to maternal and neonatal health worldwide. Early detection and treatment are crucial in reducing the morbidity and mortality of these co …
11.02.2026
Kehinde Abel Ajadi, Oluwapelumi Oyindamola Ogunleye, Adeogo Oreoluwa Jibodu, Awele Oluwayemisi Abuah, Olajide Olasubomi Diya, Benedicta Bialichukwu Onochie, Princess Okeoghene Irivradje, Oore-oluwapo Ololade Daramola, Adeleke OshoObjective Antibiotic‐induced dysbiosis predisposes hosts to colonization by opportunists such as Staphylococcus aureus , with downstream metabolic and inflammatory consequences. This study evaluated the physiological impact of dysbiosis and S. aureus challenge in rats and tested …
01.04.2026
Roopa Shri Balakrishnan, Josephine Anthony, Ashok Kumar SekarUrolithiasis, or kidney stone disease, is a chronic, recurrent disorder that significantly impacts renal health. Despite the availability of pharmacological and dietary strategies, recurrence of urolithiasis remains a major challenge. Emerging research highlights the gut–kidney a …
07.07.2026
Dr M. Ramya, B. HarshithaAlzheimer′s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, neuroinflammation, amyloid‐beta accumulation, and neuronal dysfunction. Emerging evidence suggests that the microbiota–gut–brain axis may play an important role in AD pathogen …
20.03.2026
Avishek Mandal, Sanmoy Karmakar, Mithun Bhowmick, Sweet Naskar, Ankita Sadhukhan, Arnab Sarkar, Pratibha BhowmickMalaria, an infectious disease caused by Plasmodium parasites, is a significant global health issue, particularly in tropical and subtropical regions. Understanding the development of malaria in the human body and its effects on vital organs like the liver is crucial for effectiv …
05.08.2026 · 1 Zitationen
Siddharth Singh, Vaishali Saini, Meenakshi Kandpal, Trushnal S. Waghmare, Bhupesh K. Prusty, Hem Chandra JhaThe coevolution of the human brain and microbiome has emerged as a pivotal area of research, highlighting the interactions that have shaped human development. Human accelerated regions (HARs), which are genomic sequences that evolved rapidly in humans, play an important role in b …
07.06.2026 · 2 Zitationen
Maliha Momtaj, Mohammad Nazrul Islam BhuiyanAnthocyanins are bioactive flavonoids with recognized capacity to modulate gut microbiota composition, microbial metabolism, and host physiological signaling. However, their nutraceutical and therapeutic applications are constrained by poor physicochemical stability, limited bioa …
17.03.2026 · 1 Zitationen
Adetolase Azizat Bakre, Ridwan Olamilekan Adesola, Ibrahim IdrisThe avian gut microbiota constitutes a complex, multiphyla ecosystem that critically shapes host physiology, immune function, disease resistance, and antimicrobial resistance dynamics. Bacteria, archaea, fungi, and viruses collectively regulate nutrient metabolism, mucosal barrie …
27.08.2026
Deepra Ghosh, Pritam Lenka, Swastipriya Sahoo, Sajalendu GhoshDiet and age are important determinants of the human gut microbiota, which are essential for metabolic regulation, immune homeostasis and healthy ageing. In the current study, we examined the association of vegetarian and nonvegetarian dietary patterns with gut microbiome diversi …
05.07.2026
Richa Rani, Atin Adhikari, Sudhir KumarExposure to glyphosate (GLY) or glyphosate‐based herbicides (GBHs), which are ubiquitously detected in various physical and biological matrices, has been reported to involve a crucial biological interaction between the gut microbiome and host functions. Extensive utilization of G …
27.05.2026
Amin Purhematy, Fariba Sharififar, Emmanuel Mshelia HaliluNeuroinflammatory disorders, such as Alzheimer’s disease (AD) and multiple sclerosis (MS), are increasingly recognized as systemic inflammatory syndromes rather than isolated brain pathologies. A central regulator of this systemic response is the microbiota–gut–brain axis (MGBA), …
06.09.2026
Vlada Stark, Autena Asefirad, Isabelle Kovaltchouk, Alexandrea Pitts, Amy E. L. StoneBackground Irritable bowel syndrome (IBS) is traditionally classified as a functional gastrointestinal disorder, yet it is frequently accompanied by anxiety and depressive symptoms that substantially worsen disease burden. Recent studies indicate that gastrointestinal and psychol …
27.08.2026
Benjamin Overland, Arun M. Shankregowda, Tamsyn M. Uren Webster, Matthew Hitchings, Carlos Garcia de Leaniz, Sofia ConsuegraThe gut microbiome is an important regulator of nutrition and immunity in fish, but it is highly sensitive to common aquaculture stressors (such as temperature shocks and air exposure during handling and transport) and influenced by host genetic factors, including immune function …
25.08.2026
Devabrata Saikia, Hijam Chandramani Singh, Surjya LoyingCurrent research on nutritional science focuses on the development of holistic, functionally active food matrices fortified with bioactive compounds to address chronic diseases. This review evaluates the scopes of Vigna umbellata (rice bean), an underutilized, climate‐resilient l …
02.04.2026
Meghana Shashikanth, D. B. M. VirupakshaiahHuman gut microbiome has risen as a critical nexus in the global landscape of antimicrobial resistance (AMR), acting both as a reservoir and a driver of multidrug‐resistant organisms (MDROs). This review explores the mechanistic foundations by which the gut microbiota contributes …
