EUVIMEDEuropean Health Evidence
Uhr Sources10/10 Journal Tree
Easy Demo

European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

EuropeanMultilingualInteroperableTraceable

EUVIMED BETA

EUVIMED is currently in beta

EUVIMED is under continuous development. Features, data coverage and presentation may change or be temporarily incomplete.

Results are beta

Search results, classifications, summaries and AI-assisted assessments may be incomplete, delayed or incorrect.

Check original sources

Do not use EUVIMED results without verification for diagnosis, treatment or other clinical decisions. Always consult the original source and applicable guidelines.

Errors and feedback help us improve EUVIMED: info@euvimed.com

A

Wissenschaftliches Journal · EZB

ACS Chemical Neuroscience

American Chemical Society

ISSN 1948-7193kostenlos
Artikel gesamt5.257
Aktueller Bestand1.117
Jahrgänge18
Aktuellster Jahrgang2026

Inhaltsverzeichnis

2026 · 260 Beiträge

Jahrgang 2026Online First / fortlaufend15.09.2026 · 13 Beiträge
ePub

15.09.2026

Lindsay P. Cameron, Matthew W. Johnson, Kevin S. Murnane, Mark M. Rasenick, Charles D. Nichols

Abstract Psychedelic medicine has gained rapid popularity for the treatment of a variety of neuropsychiatric disorders, including depression, anxiety, and post-traumatic stress disorder. As novel psychedelic analogues and treatment regimes emerge, increasing numbers of variables …

ePub

15.09.2026

InWook Park, Kyeonghwan Kim, Sunhee Lee, Wonbin Seo, Hye Yun Kim, Ikyon Kim, YoungSoo Kim

Abstract Fluorescence probes for visualizing amyloid-β (Aβ) plaques are important tools in Alzheimer’s disease (AD) research. We synthesized a library of 49 indolizine derivatives using a modular synthetic approach and evaluated their fluorescence labeling behavior directly in ex …

ePub

10.09.2026

Charleigh T. A. Agius, André D. J. McKenzie, Kim Woollett, Eryn L. Werry, Michael Kassiou

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with no disease-modifying therapeutics. The P2X7 receptor (P2X7R) presents as a promising target for AD drug discovery due to its pathogenic role in the onset and progression of neuroinflammation, a hal …

ePub

09.09.2026

Madiha Farooqui, Minha Fatima, Sameer Khan, Saumitra Singh, Furqan Choudhary, Tabinda Farooq, Anish Murtaja Alam Khan, Maryam Sarwat, Humaira Farooqi

Abstract Affective disorders, including major depressive disorder (MDD) and generalized anxiety disorder (GAD), impose a major global health burden because of their high prevalence, early onset, disability, and substantial social and economic impacts. Diagnosis remains challengin …

ePub

09.09.2026

Ashraf Abdo, Shaoren Yuan, Katarzyna Kuncewicz, Jisong Mo, Hongliang Duan, Moustafa T. Gabr

Abstract CAPON (NOS1AP) is an adaptor protein involved in neuronal nitric oxide synthase (nNOS) signaling and has been implicated in Alzheimer’s disease (AD), excitotoxicity, and tau-associated neurodegeneration. Here, we report the identification of cyclic peptide ligands target …

ePub

07.09.2026

Maitreyee Vaibhav Barve, Veronika Micov, Abrar Uddin, Ajmitra Gurubaran, Susmitha Madasu, Aniket Hiray, Charliene Lien, Nikesha Kelly, Matthew Sartori, Ruixiang Wang, Kathryn A. Hausknecht, Samir Haj-Dahmane, Roh-Yu Shen

Abstract Prenatal ethanol exposure (PE) causes fetal alcohol spectrum disorders (FASD), which have a high prevalence in the United States. There are various cognitive and behavioral deficits in FASD, including increased addiction risk. The diagnosis of FASD is often delayed, and …

ePub

05.09.2026

Martin N. Griffin, Daniel M. Dinakarapandian, Chenxing Li, Pranay Ramaswamy, Sia J. Saheba, Janie Lee, Tarunya Rao Sudarshan, Maria Sajimon, Christopher J. Wheeler, Jevgenij A. Raskatov, Anant K. Paravastu, Levi B. Wood

Abstract The progressive aggregation of amyloid beta (Aβ) monomers into oligomers is a critical factor in Alzheimer’s disease (AD) pathogenesis. Although mutated forms of Aβ have been shown to display altered aggregation dynamics, the specific effects of deamidated Aβ on microgli …

ePub

04.09.2026

Milind Kumar Anand, Pardhasaradhi Satha, Hariharan Moorthy, Madhu Ramesh, Sabyasachi Mandal, Thimmaiah Govindaraju

Abstract Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation and increasingly recognized as a key contributor to neurodegeneration (neuroferroptosis). Current pharmacological approaches primarily target downstream ferroptotic events and do n …

ePub

02.09.2026

Saman Rashid, Coral Crespo Gómez, Maria Dimitriadi

Abstract Spinal muscular atrophy (SMA) is a severe neuromuscular disorder caused by homozygous deletions or mutations in the SMN1 gene, resulting in reduced levels of the ubiquitously expressed survival motor neuron protein and progressive degeneration of lower motor neurons. Alt …

ePub

31.08.2026

Evelina Jankaitytė, Artu̅ras Polita, Andrius Sakalauskas, Rimgailė Tamulytė, Vytautas Smirnovas, Rima Budvytyte

Abstract The accumulation of the Aβ42 peptide is one of the key factors in the progression of Alzheimer’s disease, as it disrupts synaptic signaling and impairs neuronal function. Although the peptide is known to compromise plasma membrane integrity, the detailed mechanisms under …

ePub

31.08.2026

Santanu Singh, Sumit Kumar Singh

Abstract Alzheimer’s disease (AD), an age-associated neurodegenerative disorder characterized by cognitive decline and accumulation of amyloid-β (Aβ) plaques and tau tangles, has long been studied through the lens of protein aggregation and phosphorylation. However, emerging evid …

ePub

28.08.2026

Peibo Xu, Mei Shen

Abstract Integrated neural signaling and gut microbiome analysis are crucial for the mechanistic understanding of environmental exposure and health. Photochemical smog is a societal challenge; formaldehyde is a component of photochemical smog and a common indoor air pollutant. Al …

ePub

25.08.2026

Jordan Oman, Pooja Sapkota, Seyedeh Melika Akaberi, Sameena Mateen, Marvin Schulte, Srinath Pashikanti

Abstract l-ascorbic acid (AA), Vitamin-C, is a reductone that acts as a free radical scavenger, antioxidant, and critical cofactor in many biological pathways. Previously, AA was identified as a positive allosteric modulator (PAM) of α9α10 nicotinic acetylcholine receptors (nAChR …

Band 17Ausgabe 1702.09.2026 · 11 Beiträge
ePub

02.09.2026

10.1021/cnv017i017_2124641
ePub

02.09.2026

10.1021/cnv017i017_2124640
3203-3216

21.08.2026

Tae In Eom, Pill-Kyu Jang, Jiyun Nam, Suji Kim, Bong Hyo Lee, Suchan Chang, Hye Jin Cha, Jaesuk Yun, Chae Ha Yang, Sooyeun Lee, Seong Shoon Yoon

Abstract Menthol, a prevalent additive in tobacco and electronic cigarette products, has been reported to interact with nicotine at both neuropharmacological and behavioral levels. Although menthol alone is not reinforcing, converging evidence suggests that it may modulate the ph …

3150-3155

20.08.2026

Renan C. Ratis, Juliana S. Bonini, Angelica B. W. Bold

Abstract Extracellular protein aggregates have long been viewed primarily as toxic deposits, yet this framing fails to explain a critical clinical observation: removal of amyloid-β oligomers does not halt or reverse Alzheimer’s disease progression. Here, we propose that this para …

3229-3238

20.08.2026

Tomoteru Yamasaki, Zhiwei Xiao, Masayuki Fujinaga, Wakana Mori, Yiding Zhang, Jian Rong, Katsushi Kumata, Zhendong Song, Yusuke Kurihara, Haofeng Shi, Masanao Ogawa, Jiyun Sun, Nobuki Nengaki, Taoqian Zhao, Tomomi Kokufuta, Kazui Nakamoto, Lin Xie, Yinlong Li, Steven H Liang, Ming-Rong Zhang

Abstract Phosphodiesterase 7B (PDE7B) is involved in the cAMP-PKA signaling pathway and has been implicated in neurodegenerative disorders. Accordingly, PDE7B represents a promising target for the development of therapeutics to treat such diseases. Recent efforts have led to the …

3156-3168

20.08.2026

Min-Kyung Nam, Yeram Oh, Yemi Choi, Jieun Lee, Gi Heon Jeong, Sangjun Park, Seung-Ah Yoo, Moonseok Kim, Seongman Kang, Hyangshuk Rhim

Abstract Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons, with familial ALS (fALS) frequently caused by mutations in Cu/Zn superoxide dismutase (SOD1). The G93A mutation, one of the most aggress …

3217-3228

18.08.2026

Priyanka Tiwari, Gorantla Vikas Babu, Vikrant Rahi, Ravinder K. Kaundal, Sanjay Tiwari

Abstract Graphene quantum dots (GQDs) and their nitrogen-doped counterparts (N-GQDs) have recently been explored in the management of neurological disorders. However, their biocompatibility remains questionable, particularly subsequent to direct brain exposure. In this study, we …

3181-3191

17.08.2026

Mubaraq A. Toriola, Ethan T. Kowalczyk, Kayode M. Medubi, Michelle J. Meyer, Maya R. T. Fernando, Petra Scholze, Nethyanji Premananda, Shaun G. Harrington, Braden R. Barkley, Daniel A. Webb, Leggy A. Arnold

Abstract We report on the development of a highly water-soluble pegylated imidazodiazepine ETK-II-83. The compound binds selectively to GABAA receptors among forty-five other receptors expressed in the brain with a higher affinity for the α5-containing GABAA receptors. The compou …

3169-3180

15.08.2026

Lauren E. Honan, Sangbin Shin, W. Anthony Owens, Rebecca E. Horton, Yeon Ha Ju, Colby E. Witt, Georgianna G. Gould, Lief E. Fenno, Glenn M. Toney, Lynette C. Daws

Abstract Converging evidence implicates dysregulation of serotonin in emotion-related psychiatric disorders. Leading pharmacotherapies for such disorders, including general anxiety and posttraumatic stress disorders, target the serotonin transporter (SERT); yet, selective seroton …

3239-3251

12.08.2026

Anna Edward, Srinivas N. Puttapaka, Aravind Vulli, Shasi V. Kalivendi

Abstract The progressive loss of midbrain dopamine neurons leading to motor deficits is the primary cause of Parkinson’s disease (PD). Emerging reports on the role of NURR1 in the differentiation and maintenance of dopamine neurons; the association of reduced levels/familial muta …

3192-3202

02.07.2026

William H. Powell, Lucy E. Annett, Ronan Depoortere, Adrian Newman-Tancredi, Mahmoud M. Iravani

Abstract NLX-112 is a potent and selective 5-HT1A agonist that has successfully completed a Phase 2A clinical trial for the treatment of L-DOPA-induced dyskinesia in Parkinson’s disease (PD) patients. Here, we investigated the neuroprotective activity of NLX-112 in a mouse 1-meth …

Band 17Ausgabe 1619.08.2026 · 10 Beiträge
ePub

19.08.2026

10.1021/cnv017i016_2118766
ePub

19.08.2026

10.1021/cnv017i016_2118767
3094-3108

09.08.2026

Shubham Kumar Singh, Harsh Dinodiya, Shivay Parihar, Chiranjeevi Korupalli, Raviraj Vankayala

Abstract Alzheimer’s disease (AD) is characterized by progressive neurodegeneration and cognitive decline, largely driven by amyloid-β (Aβ) aggregation and dysregulated acetylcholinesterase (AChE) activity. While current pharmacological interventions utilize AChE inhibitors and A …

3122-3149

06.08.2026

Szu-Ying Li, Yun-Ting Kuo, Sheng-Huang Lin, Shun-An Kan, Bo-Wei Chen, Ssu-Ju Li, Ching-Wen Chang, Han-Lin Wang, Yu-Chun Lo, You-Yin Chen

Abstract Neural function emerges from the interplay between electrical activity and neurochemical signaling, yet most implantable neural interfaces primarily record electrophysiological signals and lack molecular specificity for neurotransmitter monitoring. Here, we developed a f …

3070-3081

06.08.2026

Arielle Nabatilan, Elena Sergeeva, M. Thomas Morgan, Abigail H. Wright, Larry I. Benowitz, Paul A. Rosenberg, Christoph J. Fahrni

Abstract The metal ion chelator TPEN is widely used to study the role of mobile zinc in biology; however, its high affinity for other metal ions raises questions about the specificity when interpreting biological effects of TPEN. Using the Cu(I)-selective chelator PSP-2, we found …

3109-3121

05.08.2026

Citlali Gutíerrez, Marie Mina, Jusung An, Saumitra Bhowmik, Kerui Xu, Jennifer Salaiza, Katie Chen, Tarek El Sayed, Liviu M. Mirica

Abstract With the recent FDA approval of antibody-based therapeutics for Alzheimer’s disease (AD), the need for diagnostic tools capable of detecting the disease at the earliest stages has become increasingly urgent. Although small molecules offer advantages in terms of productio …

3058-3069

04.08.2026

Girish Parmar, Kharerin Hungyo

Abstract Huntington’s disease (HD) is known for its abnormal polyQ stretch in the first exon of the HTT gene. HD is listed among the fatal autosomal dominant neurodegenerative disorders targeting the central nervous system and interfering with motor, cognitive, and psychiatric fu …

3082-3093

31.07.2026

Natalie Fuchs, Shaoren Yuan, Katarzyna Kuncewicz, Mohamed Atta Elhamouly, Farida El Gaamouch, Moustafa T. Gabr

Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is a key regulator of microglial function and a promising therapeutic target in Alzheimer’s disease. While current strategies have largely focused on antibody-based agonists, alternative modalities capable of modul …

3048-3057

28.07.2026

Oleksandr Ievglevskyi, Denis Zosen, Jordi Requena Osete, Joel C. Glover, Ragnhild Elisabeth Paulsen, Srdjan Djurovic, Elena Kondratskaya

Abstract The spinal cord exhibits a complex cytoarchitecture and neuronal circuitry organization that challenges in vitro replication of its functional integrity. Here we employed a previously published protocol to generate spinal cord organoids (SCOs) from human-induced pluripot …

3035-3047

08.07.2026

Rocío B. Foltran, Mariano Soiza-Reilly

Abstract Serotonin (5-HT) modulates a wide variety of functions across the central nervous systems. It is a key regulator of neuroplasticity, particularly in the hippocampus, where increased serotonergic signaling generally enhances the plasticity processes. However, the conseque …

Band 17Ausgabe 1505.08.2026 · 23 Beiträge
ePub

05.08.2026

10.1021/cnv017i015_2112239
ePub

05.08.2026

10.1021/cnv017i015_2112240
2933-2948

28.07.2026

Arpa Ebrahimi, Shuxin Chi, Jun Yang, Phoebe Y. Lee, Prongbaramee K. Colling, Hailey Mendenhall, Chad Giusti, David A. Hendrix, Leonard J. Foster, Claudia S. Maier

Abstract Single-cell proteomics enables direct measurement of cellular heterogeneity during dynamic biological processes, but its application to fragile and highly adherent neuronal models remains challenging. Here, we developed and applied an optimized single-cell proteomics wor …

2971-2981

27.07.2026

Aurelija Ippolito, Agnese Tiranti, Shaun Hurley, Gary Gilmour, Grant Churchill, Trevor Sharp

Abstract Current research into the actions of psychedelic drugs is focused on 5-HT2A receptor-coupled signaling pathways, particularly β-arrestin2 signaling. Here, we investigated the involvement of β-arrestin2 in psychedelic drug-induced mouse markers of hallucinogenic effects, …

2982-2990

25.07.2026

Albert W. Garofalo, Marcus D. Schonemann, Matteo Santoro, Jing Zhao, R. Jeremy Nichols, Thomas J. Montine

Abstract Gain-of-function mutations in the LRRK2 protein elevate kinase activity, and heterozygous or homozygous carriers of mutant LRRK2 have an increased risk of Parkinson’s disease (PD), together suggesting that inhibition of mutant LRRK2 kinase activity may be a promising the …

2771-2774

25.07.2026

Emona Jagaselvan, Prasenjit Mondal, Can Zhang

Abstract Emerging evidence suggests that dysregulated cellular stress responses, particularly the formation and persistence of stress granules (SGs), may significantly contribute to Alzheimer’s disease (AD) pathogenesis. SGs are dynamic, membrane-less ribonucleoprotein assemblies …

2858-2879

21.07.2026

Naveen Kumar, Venkateswarlu Yarlagadda

Abstract Alzheimer’s disease (AD) remains the leading cause of dementia, with mortality rates having doubled over the past two to three decades and projected to rise with continued population aging. Despite its profound health and economic impact, effective therapeutic and preven …

2893-2900

21.07.2026

Katsuya Morito, Suzumi Kimura, Saki Fujisawa, Yuki Nishimura, Kentaro Takayama

Abstract Repeated psychological stress is a major risk factor for psychiatric disorders. Sphingosine 1-phosphate (S1P), a bioactive sphingolipid, is known to contribute to regulating central nervous system functions. However, the relationship between the onset of psychological st …

2880-2892

20.07.2026

Xinming Zhang, Qi He, Yuan yuan Zhu, George H. Lorimer, Hasan Bayram, Reza A. Ghiladi, Jun Wang

Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that emerges in early childhood and significantly impacts the quality of life for individuals and families. Currently, there are no specific medications available for ASD. Increasing attention is now …

2823-2842

20.07.2026

Mengke Jia, Jinfei Mei, Yvning Guan, Zhi Wang, Hongqi Ai

Abstract In the pathogenesis of Alzheimer’s disease (AD), the aggregation of Aβ peptides into Aβ oligomers (AβOs) plays a critical neurotoxic role. By binding to various cell membrane receptors, AβOs can trigger abnormal intracellular signaling transduction, leading to neuronal d …

2910-2917

20.07.2026

R. Erin Jessup, Rachel S. Ehrlich, Kristine L. Teppang, Saswata Dasgupta, Christina J. Sigurdson, Jerry Yang

Abstract The accumulation of amyloid aggregates such as amyloid beta (Aβ) and tau deposits in the brain is a hallmark of many neurodegenerative diseases including Alzheimer’s disease. Recent advances in optical imaging have shown that fluorescent probes can detect amyloids in liv …

3013-3022

20.07.2026

Qinbo Qiao, Wenhui Wu, Stephanie J. Cragg

Abstract Serotonin 5-HT4 receptors (5-HT4Rs) have emerged as potential therapeutic targets in neuropsychiatric and neurodegenerative disorders by modulating circuits that shape mood, cognition, and motor functions. Ligands for 5-HT4Rs can modify dopamine (DA) and acetylcholine (A …

2949-2960

17.07.2026

Danlei Liu, Jiagui Zhong, Laijian Wang, Xiaonan Zhu, Shubin Chen, Jiong Li, Guoqing Guo, Caihui Cha, Jifeng Zhang, Guangyin Yu, Yuchuan Zhong

Abstract As a key component of the cytoskeleton, microtubule dynamics provide structural support for neurite growth. Spastin plays a critical role in reshaping microtubule arrangement, which is essential for axon development and regeneration. However, the mechanism by which spast …

2802-2817

16.07.2026

Navaneet Chaturvedi, Vaibhav Mishra, Shafiul Haque, Sabiha Khatoon, Kamal Rawal, Vijay Kumar

Abstract The dual activating potential of peroxisome proliferator-activated receptors (PPAR) α and γ offers a promising way to address metabolic issues, neuroinflammation, and protein balance in the development of Alzheimer’s disease (AD). The current study intends to underscore …

3023-3034

16.07.2026

Alexa E. Richardson, Anthony S. Ferranti, Li Peng, Xia Lei, Allie Han, Aidong Qi, Alice L. Rodriguez, Sichen Chang, Snehal Sant, Irene Zagol-Ikapitte, Srinivasan Krishnan, Analisa Thompson Gray, Joshua C. Wilkinson, Sri H. Kethanapalli, Hyekyung P. Cho, Kayla J. Temple, Dehui Mi, Emily L. Days, Joshua A. Bauer, N. Kithmini Wijesiri, Benjamin P. Brown, Olivier Boutaud, Carrie K. Jones, Darren W. Engers, Craig W. Lindsley, Colleen M. Niswender, Katherine E. Crocker

Abstract Herein, we report a potent, CNS penetrant, orally bioavailable metabotropic glutamate receptor subtype 8 (mGlu8) positive allosteric modulator (PAM), VU6081679, that shows robust efficacy in a rodent model of Parkinson’s disease. A high-throughput screening effort and su …

2843-2857

15.07.2026

Nour F. Al-Ghraiybah, Amer E. Alkhalifa, Dylan Spivey, Thomas Averill, Blake Engelkemier, Patricia Haro Lopez, Mary Grace Stuckey, Luke Jenkins, Amal Kaddoumi

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by several key hallmarks, including the accumulation of amyloid-β (Aβ), neurofibrillary tangles (NFTs), neuroinflammation, and blood–brain barrier (BBB) dysfunction. Similar to other neuro …

2918-2932

13.07.2026

Xiao-Xi Jia, Bing Xu, Chao Hu, Ru-Han A, Wei-Wei Zhang, Li-Ping Gao, Kang Xiao, Qi Shi, Cao Chen, Xiao-Ping Dong

Abstract β2-microglobulin (B2M) is implicated in neuroinflammatory and neurodegenerative processes, but its role in prion diseases remains unclear. Here, the alterations in B2M expression and distribution as well as its correlation with PrPSc accumulation were investigated in sev …

2901-2909

10.07.2026

José Alexandre Salerno, Elizabeth R. Dominguez, Karina Karmirian, Breno A.B.M.S. Arrais, Juliano Alves, Giovanna Erjautz, Kennedy Kroening, Leticia R. Q. Souza, Isis Ornelas, Stevens Rehen

Abstract The serotonergic psychedelic N,N-dimethyltryptamine (DMT) produces rapid antidepressant effects in preclinical and early clinical studies. Therapeutic benefits have been linked to sustained neural plasticity, including adult neurogenesis in rodents. Whether brief DMT exp …

2818-2822

09.07.2026

Carolina M. Vela, Josephin Wagner, Pal Pacher, Falk W. Lohoff

Abstract Cerebrovascular disease is a leading cause of death and long-term disability worldwide, most commonly manifesting as ischemic stroke. The pathogenesis of ischemic stroke is largely driven by atherosclerotic diseases of the cerebral and extracranial vasculature, where lip …

2775-2801

07.07.2026

Swati Verma, Ramesh Ambatwar, Ashok Kumar Datusalia, Gopal L. Khatik

Abstract Kynurenic acid (KYNA) is an endogenous molecule that acts as a nonselective antagonist of ionotropic glutamate receptors and has been shown to have neuroprotective properties. Although KYNA has shown considerable therapeutic potential in neurodegenerative disorders, its …

2961-2970

07.07.2026

Damian L. Stachura, Fátima Rivera-Escalera, Dion J. L. Turner, Mohd S.U. Rasheed, David M. Ruiz, Thomas D. Avery, Anibal R. Davalos, R. Jason Herr, Peter M. Grace, Andrew D. Abell

Abstract The transcription factor nuclear factor erythroid 2–related factor 2 (NRF2) is a master regulator of the antioxidant response pathway and an attractive target for treating diseases driven by oxidative stress, such as peripheral neuropathy. While activation of NRF2 by mon …

2991-2999

07.07.2026 · 1 Zitationen

Juliana Gretz, Jennifer M. Mohr, Bjoern F. Hill, Valeriia D. Andreeva, Luise Erpenbeck, Sebastian Kruss

Abstract Cells release signaling molecules such as neurotransmitters that diffuse through the extracellular space and bind to receptors. These signaling molecules can be detected by fluorescent sensors and probes to provide images of the signaling process. Such images are not equ …

3000-3012

18.06.2026

Krithi K. Bhagavath, Madhu Ramesh, Yogendra Kumar, Sabyasachi Mandal, Hiriyakkanavar Ila, Thimmaiah Govindaraju

Abstract Alzheimer’s disease (AD) is characterized by the pathological aggregation of amyloid-β (Aβ) peptides into plaques that drive neurodegeneration and cognitive decline. As Aβ remains the central and pathological biomarker for early and definitive AD diagnosis, there is a cr …

Band 17Ausgabe 1415.07.2026 · 18 Beiträge
ePub

15.07.2026

10.1021/cnv017i014_2103633
ePub

15.07.2026

10.1021/cnv017i014_2103634
2739-2751

07.07.2026

Tomayo I. Berida, Cayden J. Dodd, Joshua C. Wilkinson, Darrell R. Smith, Sichen Chang, Christopher C. Presley, Li Peng, Snehal Sant, Srinivasan Krishnan, Irene Zagol-Ikapitte, Katherine J. Watson, Analisa Thompson Gray, Alice L. Rodriguez, Hyekyung P. Cho, Carrie K. Jones, Olivier Boutaud, Colleen M. Niswender, Darren W. Engers, Paul Fernyhough, Craig W. Lindsley, Elizabeth S. Childress
2752-2770

07.07.2026

Vaishnavi Tammara, Ankita Das, Zion Desai, Atanu Das
2543-2559

06.07.2026

Xiu-Lan Jia, Tong-Hua Zhao, Wei-Hong Guo, Jing Xue, Da-Chuan Yin
2603-2619

06.07.2026

Rayla Kelly Magalhães Costa, Felipe Rodrigues Souza, Rudielson dos Santos Silva, Nicolás A. Rey, Andre Silva Pimentel
2713-2729

05.07.2026

Margaret Jane Robinson, Li Chen, Abhishek Thakur, Kuo-Hao Lee, Lei Shi
2577-2587

02.07.2026

Akila Ramesh, Ravinder Reddy, Anant Bahadur Patel
2641-2659

30.06.2026

Huong T. M. Nguyen, Elham Khajehali, Vi Pham, John W. Scott, Toby A. Dite, Laura F. Dagley, James M. Murphy, Geoff Thompson, Andrew B. Tobin, David M. Thal, Arthur Christopoulos, Emma T. van der Westhuizen, Celine Valant
2588-2602

30.06.2026

Takahiro Akasaka, Hiroyuki Watanabe, Masahiro Ono
2620-2627

26.06.2026

Guoshao Zhu, Changsheng Su, Zhenming Kang, Yangyi Li, Jianchuan Lin, Yadi Zhang
2660-2668

26.06.2026

S. Nag, V. C. Sousa, R. Zou, A. F. Morén, P. Datta, Y. Khani, A. Valade, C. Vermeiren, P. Motte, J. Mercier, H. Ågren, C. Halldin, A. Varrone
2628-2640

25.06.2026

Daniele C. Ramos, Jeane C. F. Vieira, Leonardo C. Souza, Mariza Bortolanza, Elaine Del Bel, Roberto Andreatini, Maria A. B. F. Vital
2683-2694

24.06.2026

Thuy Nguyen, Vineetha Vasukuttan, Lucas Laudermilk, Dharshini Ganeshan, Elaine Gay, Katie Hale, Samuel Banister, Julie Marusich, Michelle Glass, Rangan Maitra, Yanan Zhang
2669-2682

24.06.2026

Maria Vangelatou, Kian Stenbolt, Sylvie Bay, Karima Medjebeur, Gabriel Ayme, Pierre Lafaye, Arnaud Blondel, Laurie Peverini, Alexandre Mourot, Pierre-Jean Corringer
2730-2738

23.06.2026

Jeremy S. Coleman, Rory A. Capstick, Sichen Chang, Derek J. Rios, Michael Bubser, Analisa D. Thompson Gray, Irene Zagol-Ikapitte, Srinivasan Krishnan, Hyekyung P. Cho, Alice L. Rodriguez, Colleen M. Niswender, Olivier Boutaud, Georgina Perez Garcia, Gregory A. Elder, Darren W. Engers, Carrie K. Jones, Craig W. Lindsley
2695-2712

23.06.2026

Qinghong Liao, Xiaohan Wang, Yuetong Duan, Lina Guo, Siyu He, Weiping Lyu, Jiahe Shi, Ruihao Fu, Huachen Zhang, Yantao Han, Qi Li
2560-2576

03.06.2026 · 3 Zitationen

Hussan Adam, Sara Abdollahi, Othman Al Musaimi
Band 17Ausgabe 1301.07.2026 · 11 Beiträge
ePub

01.07.2026

10.1021/cnv017i013_2097733
ePub

01.07.2026

10.1021/cnv017i013_2097732
2504-2516

23.06.2026

Gabriel F. Martins, Cristiano Rocha, Nuno Galamba
2517-2532

22.06.2026

Shivangi Paliwal, Jayant Singh Bhardwaj, Rajeev Taliyan
2533-2542

22.06.2026

Kerui Xu, Jennifer A. Salaiza, Hammed Adeoye, Saumitra Bhowmik, Tarek El Sayed, Monika Rana, Liviu M. Mirica
2441-2453

18.06.2026 · 1 Zitationen

Phuong H. Nguyen, Philippe Derreumaux
2419-2440

17.06.2026

Meenakshi Kandpal, Harshita Shrivastava, Nfor Gael Njini, Srija Mukherjee, Sanjana Kumari, Ashutosh Srivastava, Awanish Kumar, Srikanth Karnati, Hem Chandra Jha

Abstract Neurological disorders are increasingly linked to dysfunction of key cellular organelles, including mitochondria, endoplasmic reticulum (ER), lysosomes, endosomes, and peroxisomes. These organelles coordinate essential neuronal processes via tightly regulated crosstalk. …

2486-2493

15.06.2026

Min Yang, Yuhan Wang, Jianhua Deng, Qinyue Wu, Zhangdong Wang, Qingguo Meng, Peng Wang, Jing Yang
2494-2503

11.06.2026 · 1 Zitationen

Lauren Fields, Vu Ngoc Huong Tran, Thao Duong, Tina C. Dang, Kendra G. Selby, Lingjun Li
2454-2468

29.05.2026

Bivas Talukdar, Damini Verma, Gopinath Packirisamy
2469-2485

22.05.2026

Rachit Pandey, Thomas Ruggiero, Brian Andrews, Brigita Urbanc
Band 17Ausgabe 1217.06.2026 · 15 Beiträge
ePub

17.06.2026

10.1021/cnv017i012_2092016
ePub

17.06.2026

10.1021/cnv017i012_2092017
2229-2237

08.06.2026 · 1 Zitationen

Hongjun Jin

Abstract Neuroinflammation is a central pathological process underlying neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD), and amyotrophic lateral sclerosis. Positron emission tomography (PET) molecular probes now enable the noninvasive, quantit …

2238-2261

08.06.2026 · 1 Zitationen

Yi-Bo Yuan, Miao-Miao Yin, Meng-Kang Jiang, Na Zhang, Zhi-Yu Zuo, Yan-Jun Hu

Abstract Despite substantial advances in modern medicine, neurodegenerative diseases, chronic disorders, and cancers remain major clinical challenges in which dysregulated reactive oxygen species (ROS) play a critical role. Iron oxide nanoparticles (IONPs), because of their uniqu …

2278-2301

08.06.2026 · 1 Zitationen

Anoushka Bhat, Elmira Zolali, Mahfuz A. Sakib, Mohammad Rahimian, Lance R. McMahon, Nadezhda German, Samuel Obeng

Abstract Psychedelics have re-emerged as promising therapeutics for neuropsychiatric disorders, including depression, anxiety, post-traumatic stress disorder, and substance use disorders. While their beneficial effects are largely attributed to serotonin 2A (5-HT2A) receptor acti …

2406-2418

06.06.2026 · 1 Zitationen

Caleb A. Jones, Renn A. Duncan, Kristen M. Gilliland, Carson W. Reed, Daniel H. Haymer, Paul K. Spearing, Rory A. Capstick, Bartholomew P. Roland, Paige Vinson, Marc Quitalig, Caroline Baggeroer, Natasha B. Billard, Jonathan W. Dickerson, Zixiu Xiang, Valerie M. Kramlinger, Olivier Boutaud, Julia Schlichtiger, Carrie K. Jones, Colleen M. Niswender, Hyekyung P. Cho, Jerri L. Rook, Carsten T. Wotjak, Matthias Freiwald, Riccardo Giovannini, Heiko Sommer, Scott Hobson, P. Jeffrey Conn, Bruce J. Melancon, Craig W. Lindsley

Abstract Herein, we report the discovery and development of the first-in-class (FIC), selective, and centrally active metabotropic glutamate receptor subtype 3 (mGlu3) positive allosteric modulator (PAM), VU6053371/BI03738809. A high-throughput screening campaign identified a pot …

2262-2277

04.06.2026 · 2 Zitationen

Adinath Markad, Taiba Nafis, Ashutosh Kumar Dubey, Vinod Tiwari

Abstract Chronic pain typically develops in situations such as tissue injury, inflammation, and ischemia, where extracellular acidity increases in the altered microenvironment. Acid-sensing ion channels (ASICs) are proton-gated membrane proteins that enable sensory neurons to det …

2324-2330

04.06.2026

Christopher B. Marotta, Henry A. Lester, Dennis A. Dougherty

Abstract Nicotinic acetylcholine receptors play vital roles in neuronal communication. The α5 subunit is unique, in that it assembles only into the auxiliary position (the “5th” subunit of the pentamer) of a functional receptor, yet it can have a substantial effect on a receptor’ …

2302-2318

02.06.2026 · 2 Zitationen

Siqi Guo, Qingyu Zhang, Rui Guo, Liyuan Fu, Huaxu Zhu, Qichun Zhang

Abstract Neurodegenerative disorders increasingly reflect failures of cellular state control rather than the linear accumulation of a single toxic lesion. Microglia become trapped in maladaptive states in which inflammatory activation is decoupled from effective cargo processing. …

2319-2323

01.06.2026

Anna Marie Buchanan, Sonja Virkus, N. Dalton Fitzgerald, Cesar E. Hernandez, Kirk M. Habegger, Jeremy Day, Troy A. Hackett, J. Andrew Hardaway, Aurelio Galli

Abstract Tirzepatide, a dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR), represents a new class of medication for obesity and type II diabetes treatment. Using laboratory mice, we show that GIPRs are p …

2379-2388

30.05.2026 · 1 Zitationen

Oabnithi Dornlakorn, Apiwat Sirichoat, Wanassanan Pannangrong, Nataya Sritawan, Anusara Aranarochana, Ram Prajit, Peter Wigmore, Jariya Umka Welbat

Abstract Chronic l-methionine (l-met) treatment induces hyperhomocysteinemia, which impairs neurogenesis and memory by increasing oxidative stress. Caffeic acid (CA) possesses antioxidant properties that reduce brain oxidative damage and promote neurogenesis. This study investiga …

2389-2405

30.05.2026

Jae Pyun, Asif Noor, Pranav Runwal, Celeste Mawal, Oliver K. Fuller, Casey L. Egan, Mark A. Febbraio, Paul S. Donnelly, Jennifer L. Short, Ashley I. Bush, Joseph A. Nicolazzo

Abstract Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) peptides in the brain. P-glycoprotein (P-gp), a key efflux transporter at the blood–brain barrier (BBB), plays a crucial role in the clearance of Aβ. …

2331-2347

29.05.2026 · 1 Zitationen

Fahima Madouri, Cyril Guimpied, Enora Pigeon, Nadège Hervouet, David Gosset, Pascal Auzou, Mélanie Kremer, Quentin Leboulleux, Marie-Aude Hiebel, Julie Le Bescont, Gérald Guillaumet, Franck Suzenet, Patrick Baril, Raphaël Serreau, Séverine Morisset-Lopez

Abstract The serotonin 5-HT7 receptor (5-HT7R), a member of the rhodopsin-like family of G protein-coupled receptors (GPCRs), is highly expressed in the central nervous system (CNS) and represents a promising target for treating CNS disorders such as sleep disturbances, migraine, …

2348-2363

27.05.2026 · 2 Zitationen

Grant C. Glatfelter, Serena S. Schalk, Donna Walther, Alexander D. Maitland, Nicholas R. Gonzalez, John S. Partilla, Nicholas A. Anas, Andrew R. Chadeayne, Marilyn Naeem, David R. Manke, John D. McCorvy, Michael H. Baumann

Abstract Tryptamine psychedelics induce psychoactive effects via agonist actions at serotonin 2A receptors (5-HT2A), but the compounds are generally nonselective. 4-Methoxy-N-methyl-N-isopropyltryptamine (4-MeO-MiPT) is a 5-HT2A agonist which also blocks the 5-HT transporter (SER …

2364-2378

23.04.2026

Xin Liu, Jie Liu, Pei-yang Wang, Jun-he Cui, Yu-meng Bu, Shan-shan Wu, Yan-hui Zhang, Chuang Guo

Abstract The treatment landscape for Alzheimer’s disease (AD) faces challenges such as prolonged drug development, high costs, and limited FDA-approved therapies. Given the pathological similarities between Early-Onset AD (EOAD) and Late-Onset AD (LOAD), repurposing existing drug …

Band 17Ausgabe 1103.06.2026 · 17 Beiträge
ePub

03.06.2026

10.1021/cnv017i011_2085931
ePub

03.06.2026

10.1021/cnv017i011_2085930
2086-2095

25.05.2026

Jinfei Mei, Ruhua Zha, Yuqin Qiu, Zhaoxian Du, Sitian Liang, Liangquan Sheng, Yumei Hou
2122-2131

22.05.2026

Maria Teresa Gallo, Aman Miezan Emmanuel Acquah, Luca Sbabo, Fabio Fumagalli, Paola Brivio, Francesca Calabrese
2219-2228

22.05.2026

Sashary Ramos, Matthew D. Watson, Jennifer C. Lee
2203-2218

21.05.2026

Kazi Asraful Alam, Josep Martí-Solans, Dorothea Schall, Sumit Kumar, Shahid Muhammad Iqbal, Knut Teigen, Simone Berkel, Daniela Mauceri, Bengt Erik Haug, Sara I. Liin, Timothy Lynagh, Aurora Martinez, Jan Haavik
2057-2070

20.05.2026

Fritjof Havemeister, Vesa Halipi, Marziyeh Ghaeidamini, Elin K. Esbjörner
2015-2036

20.05.2026

Poulin M., RamaRao Golime

Abstract Environmental neurotoxicants are widely used in various industries, including agriculture and public health sectors, and are known to cause harmful effects to humans through environmental and occupational exposures. Neurotoxicants are increasingly recognized as significa …

2152-2169

20.05.2026 · 1 Zitationen

Marzena Rugiel, Zuzanna Setkowicz, Agnieszka Drozdz, Aleksandra Wilk, Zofia Brylowska, Joanna Chwiej
2108-2121

18.05.2026

Wonju Kim, Yeongran Hwang, Xiao Liu, Minkyo Jung, Dongwan Ko, Srikanta Sahu, Moonseok Choi, Do-Geun Kim, Ji-Young Mun, Young-Tae Chang, Beomsue Kim
2049-2056

16.05.2026

Juan Facundo Morici, Mariana Imperatori, Pablo Koss, María Belén Zanoni, Agostina Sacson, Pedro Bekinschtein, Noelia V. Weisstaub
2071-2085

15.05.2026

Tarfah Al-Warhi, Mahmoud S. Elkotamy, Mahmoud Abdelrahman Alkabbani, Zainab M. Elsayed, Mohamed D. Morsy, Mostafa M. Elbadawi, Wagdy M. Eldehna
2096-2107

15.05.2026

Natalia Bryniarska-Kubiak, Andrzej Kubiak, Ewa Trojan, Alessandro Podestà, Małgorzata Lekka, Agnieszka Basta-Kaim
2190-2202

14.05.2026 · 1 Zitationen

Minjie Tian, Duohao Wang, Chi Zhang, Jiaxuan Fan, Wei Li, Xiangyi Liu, Jingping Shi
2132-2151

14.05.2026 · 1 Zitationen

Nithya Sree PR, Tejaswi Somarowthu, Jeyasankari S, Madhusudhana Kuncha, Sai Balaji Andugulapati, Sandip B. Bharate
2037-2048

13.05.2026 · 2 Zitationen

Linfeng Meng, Wendong Liu, Yadong Niu, Xinchen Lv, Tongbo Jin, Guanran Wang, Zhongqin Sun, Yong-Ming Wang, Ya Yang, Ying Wang
2170-2189

13.04.2026 · 1 Zitationen

Valentin Travers-Lesage, Marc Since, Alice Wang, Audrey Davis, Dimitri Fayolle, Benoit Bernay, Fabrice Modeste, Florian Nachon, Xavier Brazzolotto, Lucie Crouzier, Jana Sopkova-De Oliveira Santos, Tangui Maurice, Patrick Dallemagne, Christophe Rochais
Band 17Ausgabe 1020.05.2026 · 15 Beiträge
ePub

20.05.2026

10.1021/cnv017i010_2080440
ePub

20.05.2026

10.1021/cnv017i010_2080441
1824-1869

08.05.2026 · 1 Zitationen

Dia Panchal, Dattavi Solanki, Raghu Solanki, Amit K. Yadav, Dhiraj Bhatia, Pankaj Yadav
1955-1970

08.05.2026 · 1 Zitationen

Simon Thiou, Leslie Martin, Evangelia Manousaki, Marine Nguyen, Justine Mortelecque, Leila Heidsieck, François-Xavier Cantrelle, David Blum, Valérie Buée-Scherrer, Luc Buée, Isabelle Landrieu, Elian Dupré, Clément Danis
1989-2003

06.05.2026

Jenna M. Berger, J. Dylan Denison, A. Chathuri De Alwis, Hannah P. Sumner, Gregory S. McCarty, Elena V. Romanova, Jonathan V. Sweedler, Leslie A. Sombers
1879-1887

06.05.2026 · 1 Zitationen

Yongyu Ou, Yara A. Khatib, Adam Mosswood, Tarun K. Roy, David A. Gutierrez, David E. Olson, Jared T. Shaw
1809-1823

05.05.2026

Lorenzo Barolo, Maria Vittoria Farina, Giovanna Cimaglia, Ylenia Gigante, Anna Mirone, Lorenza Mautone, Alberto Boffi, Silvia Di Angelantonio, Paola Baiocco

Abstract Neurodegenerative diseases are characterized by progressive molecular and biochemical dysfunctions that disrupt neuronal homeostasis, leading to impaired nervous system function. In tauopathies, a specific class of neurodegenerative disorders, tau protein aggregation and …

2004-2014

05.05.2026

Haoqian Miao, Ralph Zhang, Lain X. Pierce, Ricardo DaLuz, Cole Helsell, Vicky Guan, Chae Joon Lee, Maxfield P. Benbow, Matthew N. McCarroll, Mark Mascal
1977-1988

04.05.2026

Issan Zhang, Andreas Herrmann, Ehsan Mohammadifar, Fritz Herre, Gerhard Multhaup, Rainer Haag, Dusica Maysinger
1870-1878

02.05.2026

Ángel Santiago, David Melendez-Martinez, Rodrigo Aguayo-Ortiz, Laura Dominguez
1945-1954

01.05.2026

Jason Younkin, Eda Koseli, Belle Buzzi, Edward Choi, Torin Honaker, Randall L. Davis, Dina Manetti, Maria Novella Romanelli, Aysel Cetinkaya-Fisgin, Hugo R. Arias, Ahmet Hoke, Javier Gonzalez-Maeso, M. Imad Damaj
1888-1908

30.04.2026

Ennian Li, Balaji S. Kale, Abeje A. Silte, Rui Lyu, Neha Upadhyay, Logan T. Neel, Ahmed Reda, Huiqun Wang, William L. Dewey, Piyusha P. Pagare, Yan Zhang
1919-1944

29.04.2026 · 1 Zitationen

Ahmet Hacımüftüoğlu, Nurullah Saraçoğlu, Sana Saffour, Nadeem Abad, Yunus Kesgun, Nadjiba Zegheb, Ersin Gundeger, Fatma Yeşilyurt, Merve Nur Ataş, Gizem Bati-Ayaz, Öznur Altunlu, Burak Çınar, Mehmet Ali Yörük, Ufuk Okkay, Mustafa Özkaraca, Orhan Ateş, Ali Taghizadehghalehjoughi, Ferruh Lafzi, Hasan Türkez
1909-1918

29.04.2026

Xuan Li, Lian-Lin Zeng, Xiao-Qian Jiang, Juan Yao, Li-Juan Song, Jin-He Xu, Jun-Fei Teng, Shu-Lei Liu, Bing Wu, Ke-Hui Hu
1971-1976

31.03.2026

Fatima Cheataini, Caroline Bouillot, Marco Valdebenito, Pierre Courault, Sophie Lancelot, Sandrine Bouvard, Luc Zimmer, Benjamin Vidal
Band 17Ausgabe 906.05.2026 · 18 Beiträge
ePub

06.05.2026

10.1021/cnv017i009_2074834
ePub

06.05.2026

10.1021/cnv017i009_2074835
1728-1742

28.04.2026

Huansuo Ren, Kunyuan Zhu, Hong Qu, Youcheng Li, Wei Jiang, Wenqian Chen, Xuejun Chen, Guobiao Liang, Tengfei Mao, Pengyu Pan
1779-1786

25.04.2026 · 1 Zitationen

Hongzhi Yang, Yanli Wang, Yongle Wang, Hua Cheng, Yafei Huang, Yulong Xu, Can Zhang, Changning Wang
1802-1808

24.04.2026

Yafei Huang, Yongle Wang, Yanli Wang, Hua Cheng, Hongzhi Yang, Changning Wang, Yulong Xu
1716-1727

24.04.2026

Samir Ranjan Panda, Ujjawal Soni, Pallabi Panja, Bishal Rajdev, Meenakshi Singh, Snehashis Kundu, Anagha Ranade, Sharad D. Pawar, Rabinarayan Acharya, V.G.M Naidu
1683-1692

23.04.2026

Yogyata Chawre, Manmohan L. Satnami, Ankita Beena Kujur, Akash Sinha, Prince Kumar Soni, Pinki Miri, Rekha Nagwanshi, Indrapal Karbhal, Kallol K. Ghosh
1644-1657

23.04.2026 · 2 Zitationen

Jian Yuan Yang, Wei Ming He, Wan Hua Li, Qianwen Wang, Tsz-Fung Wong, Xiaowan Jin, Dongjie Hu, Jingxuan Gao, Yilin Guo, Zhongping Yao, Deqiang Niu, Hon Cheung Lee, Ying-Chih Chiang, Yong Juan Zhao
1704-1715

21.04.2026

Hyo Gi Jung, Junho Bang, Juhyun Kim, Yeon Ho Kim, Wonbin Moon, Hyunji Kim, Jisung Yoon, Kyo Seon Hwang, Jeong Hoon Lee, Seung-Jae Lee, Jae-Yong Park, Dongtak Lee, Dae Sung Yoon
1630-1643

21.04.2026 · 1 Zitationen

Neelam, Pooja Sharma, Prabhjot Singh, Nataliia Atamas, Mohinder Kaur, Amit Dubey, Jan Paczesny, Vinod Kumar, Rohit K. Sharma, Nishima Wangoo
1670-1682

21.04.2026 · 1 Zitationen

Maxemiliano V. Vargas, Cassandra J. Hatzipantelis, Lee E. Dunlap, Robert J. Tombari, Arabo A. Avanes, Sam Vaillancourt, Pierre Llorach, Juliana S. Salgado, Boris D. Heifets, David E. Olson
1743-1765

17.04.2026

Arunabh Choudhury, Mohammad Umar Saeed, Sneh Prabha, Md. Imtaiyaz Hassan
1766-1778

16.04.2026

Shivam Tiwari, Bhubaneswar Mandal, K. Anki Reddy
1693-1703

15.04.2026

Noëlle van Egmond, Elisabeth A. Jalink, Daan van der Vliet, Anniek J. Henselijn, Marleen E. Ridder, Berend Gagestein, Anna F. Stevens, Sander I. van Kasteren, Mario van der Stelt
1658-1669

15.04.2026

Yuqi Cheng, Cuicui Jiang, Zhenhui Zhang, Xiaowen Zheng, Zihan Zhang, Haifeng Lu, Qunlin Zhang
1602-1610

14.04.2026

Jessica M. Lin, Benjamin Baah Konadu, Darci J. Trader, Hai-yan He

Abstract The proteasome is a major organelle responsible for protein degradation in neurons and has been implicated in the regulation of signal transduction and activity-dependent plasticity mechanisms that are essential for normal neuronal function. However, our understanding of …

1787-1801

13.04.2026 · 1 Zitationen

Chandan Chauhan, Paarth Kumar, Harapriya Baral, Tara Datt Bhatt, Joydev K. Laha, Maneesh Kashyap, Ravinder K. Kaundal
1611-1629

25.03.2026

Ankita Devi, Shashi Bala Singh, Saurabh Srivastava, Manoj P. Dandekar
Band 17Ausgabe 815.04.2026 · 15 Beiträge
ePub

15.04.2026

10.1021/cnv017i008_2066838
ePub

15.04.2026

10.1021/cnv017i008_2066837
1530-1539

03.04.2026 · 1 Zitationen

Yasaman Doroudian, Melissa Schepers, Tim Vanmierlo, Lennart Bunch
1555-1565

02.04.2026 · 1 Zitationen

Bivek Chaulagain, Avinash Gothwal, Arun Kumar Mahanta, Yagna P. R. Jarajapu, Jagdish Singh
1566-1578

02.04.2026 · 1 Zitationen

Xiang Zuo, Huijuan Bai, Qili Zhao, Xin Zhao, Xizeng Feng
1505-1515

30.03.2026

Priyajit Kaur, Sakshi Kumari, Abhinay Kumar Singh, Tirthankar Koley, Nitish Rai, Ethayathulla Abdul Samath, Sharmistha Dey
1579-1592

30.03.2026

Lei Ortigosa-Pascual, Noemi Ferrante Carrante, Katja Bernfur, Katarzyna Makasewicz, Emma Sparr, Sara Linse
1593-1601

30.03.2026 · 1 Zitationen

Alyssa Moore, Xiaoling Chen, Emerson Hernly, Jingliang Zhang, Yang Yang, Julia Laskin
1432-1461

29.03.2026 · 2 Zitationen

Feyza Sule Aslan, Beyza Barut, Sudenaz Ozturk, Tugba Eyigurbuz, Enes Akyuz
1469-1478

27.03.2026

Yoko Hirata, Yui Kobatake, Hiroko Koyama, Kyoji Furuta, Hiroshi Takemori, Yuji O Kamatari
1516-1529

27.03.2026

Courtney J. Wright, Silas A. Buck, Snezana Milosavljevic, Ashley M. Lewis, Nathan T.J. Wagner, Ana Pocivavsek
1490-1504

25.03.2026

Jaqueline Dantas Neres Martins, Lisa Maria Mendes de Almeida Souza, Leonardo Yuji Nihira Alencar, Pedro Henrique Freitas de Almeida, Caio Demetrius de Lima Meireles, Sávio Monteiro dos Santos, Kely Campos Navegantes Lima, Gabriel Mesquita da Conceição Bahia, Luana Ketlen Reis Leão da Penha, Anderson Manoel Herculano Oliveira da Silva, Karen Renata Herculano Matos Oliveira, Carlomagno Pacheco Bahia, Marta Chagas Monteiro
1540-1554

24.03.2026

Qihao Wang, Luqi Gao, Xiaoshan Yang, Bo Chen, Wenchen Li, Haifeng Wang
1479-1489

24.03.2026 · 1 Zitationen

Precious Earldom Mulaudzi, Heidi Abrahamse, Anine Crous
1462-1468

24.03.2026

Filippo Turchi, Haydar Taylan Turan, Marco Schiavina, Giuseppe Brancato, Isabella C. Felli, Roberta Pierattelli
Band 17Ausgabe 701.04.2026 · 17 Beiträge
ePub

01.04.2026

10.1021/cnv017i007_2060942
ePub

01.04.2026

10.1021/cnv017i007_2060941
1387-1400

23.03.2026

Viet Hoang Man, Xibing He, Taoyu Niu, Lianjin Cai, Fengyang Han, Phuong Nguyen, Junmei Wang
1362-1374

23.03.2026

Abhilasha A. Doke, Mona S. Kirmire, Anjali Jha, Santosh Kumar Jha
1345-1361

23.03.2026 · 2 Zitationen

Soni Tiwari, Zaidan Mohammed, Santi Ranjan Atta, Aryan Tiwari, Ekta Yadav, Shweta Kaushik, Amla Chopra, Itender Singh, Simantini Ghosh
1256-1268

20.03.2026

Eline Pottie, Emma Vertriest, Darío Martínez-Afani, Breno A. Soares, Bruce K. Cassels, Christophe P. Stove
1375-1386

20.03.2026

Kavita A. Iyer, Xiaolei Pan, Charles B. Jones, Hebing Liu, Malaika D. Argade, Osama I. Alwassil, Douglas H. Sweet, Małgorzata Dukat
1229-1232

19.03.2026

Komal Jindal, Shallu Sharma, Pravat K. Mandal
1303-1315

19.03.2026 · 3 Zitationen

Larry Rodriguez, Jolene Diedrich, Le Sun, Blake Tsu, Stefanie Kairs, Roman Vlkolinsky, Christopher A. Barnes, Aline M. A. Martins, Marisa Roberto, John R. Yates
1401-1414

17.03.2026

Paulina Kazmierska-Grebowska, Jacek Grebowski, Michał Żebrowski, Gino A. DiLabio, Oskar Ciesielski, Aneta Balcerczyk, Hugo R. Arias, Grzegorz Litwinienko
1415-1431

17.03.2026 · 2 Zitationen

Yuyi Hou, Guolong Huang, Yongshan Liu, Yifan Qiu, Peizhen Ye, Lei Bi, Pengcheng Zheng, Yanjun Xu, Sirui Wu, Caichuan Wei, Hongjun Jin
1286-1302

13.03.2026 · 2 Zitationen

Yoongyeong Baek, Anika Alim, Yanheng Dong, Tarek Olabi, Jungwook Paek, Myungwoon Lee
1245-1255

12.03.2026

Sophie A. M. Steinmüller, Alix C. Flake, Marcel Bermudez, Peter Ashdown, James N. Hislop, Michael Decker
1316-1331

12.03.2026

Sean McNeme, Anil Kumar, Yun Young Yim, Brandon W. Hughes, Corey St. Romain, Yi Li, Ashwani Kumar, Qichao Bao, Molly Estill, Shanghua Fan, Nadeen Takatka, Earnest P. Chen, Matthew Rivera, Haiying Chen, Alfred J. Robison, Mischa Machius, Stephen J. Haggarty, Jeannie Chin, Eric J. Nestler, Jia Zhou, Gabby Rudenko
1233-1244

12.03.2026

Junyue Tang, Yuning Sun, Xingyu Lin, Xinhui Zhao, Chun Mao, Mimi Wan, Jianying Li, Ya Guan
1332-1344

11.03.2026

Noelia Castedo, Amparo Alfonso, Rebeca Alvariño, Dawrin Pech-Puch, Lucía Ageitos, Jaime Rodríguez, Mercedes R. Vieytes, Carlos Jiménez, Luis M. Botana
1269-1285

27.02.2026 · 1 Zitationen

Lynn Ana Flavia Salamanca-Guillén, Liana Melo-Thomas, Kelly C. S. Roballo, André Schwambach Vieira, Bruno Henrique de Melo Lima, Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira
Band 17Ausgabe 618.03.2026 · 17 Beiträge
ePub

18.03.2026

10.1021/cnv017i006_2055362
ePub

18.03.2026

10.1021/cnv017i006_2055363
1054-1055

10.03.2026

Leslie Sombers, Parastoo Hashemi
1145-1158

10.03.2026 · 1 Zitationen

Nadia Allahyarzadeh Khiabani, Avery Russel-Jay Elmhirst, Osheen Dubey, Arjun Poudel, Mayank Singh, Hannah Monville, Andrew Sahouri, Yousef Alani, Douglas Swanson, Gary L. Dunbar, Julien Rossignol
1195-1210

06.03.2026

Manvendra Kumar, Shubham Upadhayay, Pritam Maity, Sourav Das, Uttam Kumar Mishra, Peeyush Shrivastava, Balram Singh Lodhi, Deepak Chouhan, Ashoke Sharon, Puneet Kumar, Ashutosh Kumar, Vinod Tiwari, Raj Kumar
1185-1194

05.03.2026 · 3 Zitationen

Giheon Kim, Seungjun Lee, Jonghee Eun, Namsun Chou, Hyogeun Shin
1104-1114

05.03.2026

Siddhanta V. Nikte, Durba Sengupta, Amitabha Chattopadhyay
1227-1228

04.03.2026

Nina Kastner, Núria Nadal-Gratacós, Selina Hemmer, Leticia Alves da Silva, John L. McKee, Tamara Hell, Giulia Cicalese, Marion Holy, Fatemeh Kooti, Kathrin Jäntsch, Ricarda Baron, Naomi Shacham, Bruna Cuccurazzu, Adam L. Halberstadt, John D. McCorvy, Thomas Stockner, Markus R. Meyer, Raúl López-Arnau, Matthias Grill, Harald H. Sitte
1171-1184

03.03.2026

Samuel E. Williamson, Elise K. Burkhartzmeyer, Michael T. Faley, Rachel F. Ohana, Ilia A. Guzei, Mike Valley, James J. Cali, Alexander M. Sherwood
1056-1063

03.03.2026

Nav Raj Phulara, Kadia Lissit, Yuejia Huang, Jin-Chong Xu, Herana Kamal Seneviratne
1064-1077

02.03.2026

Jingwen Li, Tingting Liu, Jianshe Wei
1211-1226

02.03.2026 · 1 Zitationen

Rachel Sim, Jeremy Lee, Joey Chieng, Ko Hui Tan, Grace Lim, Aaron Foo, Sunny Hei Wong, Kah Leong Lim, Kaicheng Liang
1078-1087

25.02.2026

Xiaotong Zheng, Xiaoyu Liu, Yuehong Yu, Tianmei Liu, Xiaolei Zhu, Yao Cen, Kai Kang, Fan Zhang
1159-1170

25.02.2026 · 1 Zitationen

Pomme M. F. Rigter, Karel Bezstarosti, Oguz Can Koc, Tyler L. Perfitt, Jeroen A. A. Demmers, Roger J. Colbran, Margaret M. Stratton, Ype Elgersma, Geeske M. van Woerden
1129-1144

25.02.2026

Nancy Vela Navarro, Gustavo De Nadai Mundim, Deepika Regmi, Ivet Boneva, Ramya Ayyalasomayajula, Maria E. Vezzi, Valentina Sopo Borraez, Alexis Crowder, Alejandra Coronel-Zegarra, Hasham Shafi, Heidi M. Mansour, Vivian Merk, Deguo Du, Dmitriy Minond, Maré Cudic
1088-1103

24.02.2026 · 1 Zitationen

Yixiao Liu, Zexuan Hu, Yitong Xiao, Xinyuan Han, Xiaorui Cheng, Tianyuan Ye
1115-1128

09.02.2026

Matteo Rossi Sebastiano, Antonio Vicidomini, Serena Francisco, Verdiana Pullano, Paola Defilippi, Gabriele Baj, Fabrizia Cesca, Giulia Caron, Giuseppe Ermondi
Band 17Ausgabe 504.03.2026 · 16 Beiträge
ePub

04.03.2026

10.1021/cnv017i005_2049871
ePub

04.03.2026

10.1021/cnv017i005_2049872
946-961

23.02.2026

Teja Kumar Ponduri, Chakravarthi Guntupalli, Balamurugan Jeganathan, Narender Malothu
987-997

20.02.2026 · 3 Zitationen

William Le Boeuf, Ahmed A. Hefny, Rahul C. Karuturi, Praveen P.N. Rao
932-945

20.02.2026

Mahzad Irandoust, Atiyeh Ghasemi, Ahmed A. Abdul-Azeez Al-Safar, Ali H. A. Kelkawi, Mahya Mohammad-Zaheri, Ali Akbar Saboury, Arefeh Seyedarabi
962-975

19.02.2026 · 2 Zitationen

Alex R. Lovins, Kevin A. Miller, Rose K. Homoelle, Hayden J. Hoover, Craig A. McElroy, Christopher S. Callam, Christopher M. Hadad
899-919

18.02.2026 · 3 Zitationen

Audrey Hannum, Isabella Spano, Edward Ofori
976-986

18.02.2026 · 2 Zitationen

Dima Bolmatov, Russel J. Reiter, Dmitry Zav’yalov, Changwoo Do, Gergely Nagy, Charles Patrick Collier, John Katsaras, Maxim O. Lavrentovich
1043-1053

18.02.2026

Vito F. Palmisano, Micaela Vidal−Sánchez, Juan J. Nogueira
1031-1042

17.02.2026

Alice Y. C. Liu, Kelvin Y. Kwan, Clarissa Kwan, Kuang Yu Chen
886-898

16.02.2026

Georgios Spyridon Ousta, Christos Adamopoulos, Christina Piperi
1015-1030

16.02.2026 · 1 Zitationen

Panpan Zhang, Ying Liu, Mingxuan Lv, Hanbo Pan, Mengqi Zhang, Zhengxin Liu, Wenshi Wei, Aijuan Yan
848-869

16.02.2026

Shima Mohammadi, Tahereh Ghorbandaiepour, Maryam Zahmatkesh, Leila Karimi-Zandi, Ali Mirzakhani
920-931

12.02.2026

Hongbin Liang, Xueqin Zheng, Yanping Liu, Chao Fu, Long Wang, Wanyou He, Han-bing Wang
870-885

12.02.2026 · 1 Zitationen

Himani Nautiyal, Kuldeep K. Roy, Shubham Dwivedi
998-1014

29.01.2026 · 1 Zitationen

Flavia B. Lopes, Tobias Werner, Izilda A. Bagatin, Holger Stark, João Paulo S. Fernandes
Band 17Ausgabe 418.02.2026 · 16 Beiträge
ePub

18.02.2026

10.1021/cnv017i004_2043485
ePub

18.02.2026

10.1021/cnv017i004_2043486
666-680

10.02.2026 · 10 Zitationen

Yingjun Chen, Weiwei Xue
719-739

09.02.2026

Tallan Black, Rhiannon E. Boseley, Amanda Quirk, Kaylen M. Young, Sarah Lunardi-Baccetto, Brett D. Muyres, Robert B. Laprairie, John G. Howland
778-790

05.02.2026 · 2 Zitationen

Dan Yang, Yilin Song, Shihui Yu, Youzhen Ma, Wenlong Du
791-804

05.02.2026

Ruben Torres, Oleg Kovtun, James R. McBride, Laurel G. Bellocchio, Sandra J. Rosenthal
701-718

05.02.2026 · 3 Zitationen

Teja kumar Ponduri, Chakravarthi Guntupalli, Balamurugan Jeganathan, Narender Malothu
740-751

05.02.2026 · 1 Zitationen

Dongni Wen, Yunjing Li, Lina Chen, Haoling Xu, Yingqing Wang, Yanhong Weng, Jing Zhang, Xiaochun Chen, En Huang, Yuqi Zeng, Qinyong Ye
846-847

04.02.2026

Sharif Arar, Md Anzarul Haque, Nemil Bhatt, Yingxin Zhao, Rakez Kayed
689-700

03.02.2026

Muhammad Junaid Tariq, Madiha Kanwal, Athar Ata, Humaira Nadeem, Mahwish Siddiqui
681-688

30.01.2026 · 1 Zitationen

Belén Machin, Silvana Soliz Santander, Agustín O. Pernicone, Eva M. M. Velez, Verónica E. Manzano, Florencia González-Lizárraga, Rossana E. Madrid, César L. Avila, Esteban Vera Pingitore, Oscar Varela, Rosana Chehín
823-832

29.01.2026 · 1 Zitationen

Yana Purvinsh, Mikhail Matveyenka, Dmitry Kurouski
752-766

28.01.2026

Nikhil R. Shah, Wesley B. Corey, Camden N. Harris, Anthony J. Baucum
833-845

28.01.2026 · 5 Zitationen

Ashish Kumar, Tanmay Mondal, Madhu Ramesh, Jikesh Bhoi, Sourav Samanta, Thimmaiah Govindaraju
767-777

28.01.2026 · 2 Zitationen

Vikrant Rahi, Swapnil Sharma, Ravinder K. Kaundal
805-822

27.01.2026 · 2 Zitationen

Kora Reichau, Lucie Crouzier, Eleonora Poeta, Tina Gehrig, Eva Schaller, Liga Zvejniece, Johann Meunier, Christoph Sotriffer, Barbara Monti, Tangui Maurice, Michael Decker
Band 17Ausgabe 304.02.2026 · 15 Beiträge
ePub

04.02.2026

10.1021/cnv017i003_2037031
ePub

04.02.2026

10.1021/cnv017i003_2037030
565-575

26.01.2026

Yu-Quan Wang, Wen-Bo Liu, Wen-Qiang Cui, Tong-Tong Guo, Teng Chen, Wen-Shan Sun, Yu-Xia Chu
599-609

26.01.2026 · 4 Zitationen

Zsofia Digby, Christine Diamond, Heather Wescott, Pam Smolak, Peter Thornton, Nicola Lindsay, Christopher A. Gabel, Nicholas Clarke, Alan P. Watt
610-623

26.01.2026

Scott H. Henderson, Anna E. Ringuette, David L. Whomble, Rory A. Capstick, Alexa E. Richardson, Mallory A. Maurer, Natasha B. Billard, Xia Lei, Joshua C. Wilkinson, Sri H. Kethanapalli, Hyekyung P. Cho, Alice L. Rodriguez, Colleen M. Niswender, Weimin Peng, Jerri M. Rook, Sichen Chang, Anna L. Blobaum, Olivier Boutaud, Andrew S. Felts, P. Jeffrey Conn, Craig W. Lindsley, Kayla J. Temple
649-665

25.01.2026

Alison R. Gregro, Charlotte Park, Madeline F. Long, Logan A. Baker, Katrina A. Bollinger, Anna E. Ringuette, Li Peng, Vincent B. Luscombe, Natasha B. Billard, Alice L. Rodriguez, Colleen M. Niswender, Weimin Peng, Jonathan W. Dickerson, Jerri M. Rook, Jordan O’Neill, Sichen Chang, Harrie C. M. Boonen, Thomas Jensen, Morten S. Thomsen, Thomas M. Bridges, Olivier Boutaud, P. Jeffrey Conn, Darren W. Engers, Craig W. Lindsley, Kayla J. Temple
592-598

23.01.2026 · 2 Zitationen

Emil Axell, Andreas Carlsson, Max Lindberg, Katja Bernfur, Emma Sparr, Sara Linse
635-648

23.01.2026

Bulat I. Khairutdinov, Diliara R. Khaibrakhmanova, Evgeniia V. Leisi, Ekaterina R. Sidorova, Yegor A. Sofronov, Vladimir I. Muronetz, Yuriy F. Zuev, Igor A. Sedov
537-549

23.01.2026

Parul Sharma, Rohit Goyal
576-591

21.01.2026 · 2 Zitationen

Diksha, Abhishek Kumar, Smita Saha, Vishal Gaurav, Yogendra Pratap Mathuria, Akash Ranjan, Shailesh Kumar Gupta, Debasish Kumar Ghosh
478-503

21.01.2026 · 3 Zitationen

Xu Yan, Hangyu Shen, Mingyue Zhao, Sheng Nie, Yi Huang, Jie Sun
525-536

15.01.2026

Lin Liu, Yang Yang, Zhongyuan Qu, Shuang Wu, Xiang Zou, Dongxue Wang
624-634

14.01.2026 · 2 Zitationen

Daniel C. Schultz, Lauren C. Parr, Hunter Sweet, Sean Lamb, Julie L. Engers, Nathaniel C. Napier, Hallie G. McKinnie, David Whomble, Valerie Kramlinger, Olivier Boutaud, Craig W. Lindsley
550-564

14.01.2026 · 2 Zitationen

Lily Henry, Shayon Bhattacharya, Talia Bergaglio, Dorothea Pinotsi, Peter Niraj Nirmalraj
504-524

12.01.2026

Diksha Rani, Nitesh Priyadarshi, Deepti Goyal, Nitin Kumar Singhal, Bhupesh Goyal
Band 17Ausgabe 221.01.2026 · 11 Beiträge
ePub

21.01.2026

10.1021/cnv017i002_2031737
ePub

21.01.2026

10.1021/cnv017i002_2031738
465-477

10.01.2026 · 1 Zitationen

Muhammad Noman, Halima Qadir, Sagheer Ahmed, Najeeb Ur Rehman, Fawad Ali Shah, Muhammad Riaz, Nadeem Ahmad, Zaheer Ul-Haq, Nadeem Irshad
423-439

09.01.2026

Valeria Francesconi, Anna Carbone, Gabriella La Spada, Davide Odino, Claudio Canale, Annalisa Relini, Sabrina Pricl, Marco Catto, Michele Tonelli
367-381

08.01.2026

Yu Lei, Meimei Guo, Shilin Zhang, Yutuo Zheng, Jiawei Hao, Yuhan Liu, Jiabin Zhou
335-351

07.01.2026 · 3 Zitationen

Charalampos L. Kandilakis, Costas Papatheodoropoulos
352-366

07.01.2026 · 1 Zitationen

Yutaka Itokazu, Wayne D. Beck, Alvin V. Terry
382-391

06.01.2026 · 5 Zitationen

Miguel Salfiti, Marios Kyriazis, Georgios Mikellides
450-464

05.01.2026 · 2 Zitationen

Hope Pan, Xinyi Cheng, Jeffrey Zhang, Ke Hou, Kevin A. Murray, Kapil Manglani, Cansheng Zhu, Hung-Kai Hsu, Marisa Mekkittikul, Tyler Halladay, Hilda Mirbaha, Gazmend Elezi, Romany Abskharon, Michael R. Sawaya, Alexander Bombino, Christopher K. Williams, Michael DeTure, Dennis W. Dickson, Harry V. Vinters, Julian P. Whitelegge, Patrick G. Harran, Gregory M. Cole, Sally A. Frautschy, David S. Eisenberg
440-449

02.01.2026 · 1 Zitationen

Mario de la Fuente Revenga, Javier González-Maeso
392-403

02.01.2026

Avijit Banik, Radhika Amaradhi, Michael Sau, Varun Rawat, Raymond Dingledine, Thota Ganesh
Band 17Ausgabe 107.01.2026 · 2 Beiträge
ePub

07.01.2026

10.1021/cnv017i001_2024473
ePub

07.01.2026

10.1021/cnv017i001_2024472
EUVIMED Journal ReaderACS Chemical Neuroscience