Acta Anaesthesiologica Scandinavica

13.09.2026

Measuring What Matters: Advancing Research on Intraoperative Pain During Cesarean Birth

10.09.2026

Application of the Quadratus Lumborum Block in Pediatric Gastrointestinal Surgery: A Scoping Review

ABSTRACT Background Effective pain control is critical in pediatric gastrointestinal surgery to support recovery and improve postoperative outcomes. Regional anesthetic techniques have gained increasing interest, with the quadratus lumborum block (QLB) emerging as a promising opt …

10.09.2026

General Versus Spinal Anaesthesia for Outpatient Arthroplasty: The Potential Role of Patient Preference

10.09.2026

Intracerebral Glutamate and Glycerol in Severe Acute Brain Injury: Retrospective Study of Association With Neuroworsening and Outcome

ABSTRACT Background Glutamate is the main excitatory neurotransmitter in the brain, and extracellular levels of glutamate and glycerol (a breakdown product of cell damage) increase after severe acute brain injury. Previous studies report that increased intracerebral glutamate—mea …

04.09.2026

Perioperative Use of Vasoactive Agents in Patients Undergoing Gastrointestinal Surgery: A Protocol for a Scoping Review

ABSTRACT Background Perioperative hypotension in patients undergoing gastrointestinal surgery is a known and well‐described condition. Timely treatment of perioperative hypotension, regardless of the reason, is important in order to reduce the associated postoperative complicatio …

04.09.2026

“Free of Delirium” Must Not Mean “Never Assessable” in CoreMS ‐ ICU

04.09.2026

The Association Between Postoperative Fluid Balance and Postoperative Complications in Adults Undergoing Gastrointestinal Surgery: Protocol for a Scoping Review

ABSTRACT Background Fluid balance in patients who have undergone gastrointestinal surgery is known to be challenging to monitor, resulting in imprecise and inaccurate measurements. Despite this knowledge, any association between fluid balance accuracy and the development of posto …

31.08.2026

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Se …

31.08.2026

Clinicians' Perspectives on Pre‐Anaesthetic Assessment and Their Attitudes Towards AI ‐Supported Models: Protocol for an International Survey of Anaesthesia Personnel

ABSTRACT Background Pre‐anaesthetic assessment is essential for safe perioperative care but is resource‐intensive and applied variably in clinical practice. Increasing surgical demand and workforce constraints have prompted interest in alternative models, including digital approa …

28.08.2026

Abstracts from the 2026 Congress of the Scandinavian Society of Anesthesiology and Intensive Care Medicine, Reykjavik, Iceland, June 10–12, 2026

27.08.2026

The Use of Intravenous Clonidine in Postoperative Pain Management: A Scoping Review

ABSTRACT Background Clonidine, an alpha‐2 receptor agonist, has been explored as a potential analgesic in postoperative pain management, but its efficacy and safety profile remain unclear. The aim of this scoping review was to present the evidence on the use of intravenous clonid …

27.08.2026

Anaesthetic Techniques for Cardiac Ablation—A Scoping Review

ABSTRACT Background Cardiac arrhythmias, particularly atrial fibrillation, have rising prevalence and represent a growing global health burden. Catheter ablation is a commonly used treatment demanding sedation or anaesthesia for comfort, stability and safety. Anaesthetic techniqu …

26.08.2026

Airway Management Practices in Burn Patients: A Protocol for a Scoping Review

ABSTRACT Background Loss of airway represents a serious clinical concern in the management of burn patients and frequently prompts early intubation. However, intubation itself carries inherent risks and is not invariably required for optimal care. Concern over the potentially sev …

24.08.2026

Acute Pain During Intensive Care: Prevalence, Predisposing Factors and Pain Trajectories. A Prospective Multicenter Observational Study

ABSTRACT Background A considerable proportion of patients in the intensive care unit (ICU) experience pain. The objective of this prospective observational cohort study was to investigate the prevalence of pain, factors associated with pain and pain trajectories in ICU patients. …

23.08.2026

Issue Information

23.08.2026

Prehospital Transfusion With Red Blood Cells and Fresh Plasma in Helicopter Emergency Medical Services

ABSTRACT Background Prehospital administration of blood products is a growing practice. We aimed to describe clinical parameters and mortality following prehospital blood component therapy with red blood cells (RBC) and/or plasma in patients with traumatic and non‐traumatic haemo …

23.08.2026

Anaesthetic Type and Survival in Metastatic Colorectal Cancer: A Nationwide Registry Study

ABSTRACT Background The impact of anaesthetic choice on survival following metastatic cancer surgery is uncertain. Inhalational anaesthetics, such as sevoflurane, may promote inflammation and tumour progression, while the intravenous agent propofol has been suggested to be anti‐i …

11.08.2026 · 1 Zitationen

Blood Pressure Targets During General Anaesthesia in High‐Risk Patients—A Randomised Clinical Feasibility Trial

ABSTRACT Background There is limited high‐quality evidence to guide haemodynamic and respiratory management during general anaesthesia. The goal of this trial was to test the feasibility of testing different ventilatory settings and blood pressure targets. Previous trials on bloo …

05.08.2026

Coagulopathy in Critically Ill Patients With Sepsis: Protocol for a Scoping Review

ABSTRACT Background Coagulopathy is a common complication in patients with sepsis, ranging from subclinical coagulation activation only seen in laboratory values to disseminated intravascular coagulation ( DIC ). Over the past 25 years, several scoring systems have been developed …

04.08.2026

Nerve Injury Following Birth, the Role of Epidural Analgesia—A Protocol for a Scoping Review

ABSTRACT Background Epidural analgesia is widely used during labor, and postpartum nerve injury is an uncommon but clinically relevant outcome. Neurological symptoms after childbirth may be related to obstetric or anesthetic factors. Studies vary considerably in how postpartum ne …

02.08.2026

Development and Clinical Utility of Machine Learning Models for Prediction of Same‐Day Discharge in Outpatient Hip and Knee Replacement: A Prognostic Study

ABSTRACT Background Hip and knee replacement are common procedures with an increasing focus on same‐day surgery. However, capacity constraints limit the number of eligible patients actually being scheduled for same‐day discharge, calling for further selection of those with the hi …

31.07.2026

Use of Coercion or Persuasion in Prehospital Treatment in the Region of Southern Denmark: A Retrospective Study

ABSTRACT Background The use of coercion or persuasion raises ethical challenges but may be justified when prehospital patients require immediate treatment and are unable to consent. This study aims to describe the characteristics of coerced or persuaded adult pre‐hospital patient …

29.07.2026

Prehospital Normoventilation in Critically Ill Anaesthetised Patients Cannot Be Reliably Monitored by Capnography—A Retrospective Observational Study

ABSTRACT Background End‐tidal carbon dioxide capnography (EtCO 2 ) is widely used to guide intubated patients' ventilation. Current guidelines for prehospital advanced airway management assume a gradient of approximately 0.67 kPa between EtCO 2 and arterial carbon dioxide partial …

29.07.2026

Prehospital PEEP for Acute Respiratory Distress: Protocol for a Scoping Review

ABSTRACT Background Positive end‐expiratory pressure (PEEP) can improve oxygenation and reduce the work of breathing in patients with acute respiratory distress. In the prehospital setting, systems providing continuous positive airway pressure (CPAP), bi‐level positive airway pre …

29.07.2026

Video‐Based Tool for Assessment of Airway Management With Flexible Laryngeal Mask in Clinical Practice—A Protocol for a Study Gathering Validity Evidence

ABSTRACT Background Flexible laryngeal mask airway (fLMA) devices are widely used in head, neck, and oral surgery, but insertion can be technically challenging, and inadequate placement may compromise ventilation. Competency‐based training requires trustworthy assessment instrume …

28.07.2026

International Consensus on Airway Management Procedures for Distance Simulation: A Delphi Study

ABSTRACT Background Airway management is a core clinical competency, yet consistent and patient‐safe hands‐on training opportunities remain limited. Distance simulation, in which learners and facilitators are in different physical locations, may expand access to technical skills …

27.07.2026 · 1 Zitationen

Positive End‐Expiratory Pressure, Tidal Volume, and Fraction of Inspired Oxygen During General Anaesthesia in High‐Risk Patients—A Randomised Clinical Feasibility Trial

ABSTRACT Background Optimal ventilatory settings during general anaesthesia are unknown. The goal of this trial was to test different ventilatory settings and blood pressure targets during general anaesthesia. This manuscript focuses on the ventilatory interventions. Methods This …

26.07.2026

Impaired Pre‐Critical Illness Quality of Life in Elderly ICU Patients

ABSTRACT Background The EuroQol EQ‐5D‐5L is recommended to assess health‐related quality of life (HRQoL) in intensive care unit (ICU) survivors and included in many national ICU registries at the time of follow‐up. While establishing baseline HRQoL in elderly ICU survivors is imp …

23.07.2026

Rebound Pain and Patient Satisfaction With Dexamethasone as an Adjunct for Peripheral Nerve Blocks. A Substudy Based on Two Randomised Clinical Trials

ABSTRACT Background Peripheral nerve blocks (PNBs) are a cornerstone in postoperative pain management, reducing pain, opioid consumption, and opioid‐related adverse effects. However, the duration of PNBs is limited and might result in rebound pain after block cessation. Dexametha …

23.07.2026

Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis

ABSTRACT Introduction The liver is essential for bacterial elimination, preventing intestinal bacteria from entering the systemic circulation, and for producing inflammatory cytokines. Glucocorticoids have been reported to exert heterogeneous effects on bacterial clearance in sep …

21.07.2026

Issue Information

21.07.2026

Perioperative Changes in Blood Volume and Fluid Distribution in Total Hip Arthroplasty—A Protocol for a Prospective Single‐Center Observational Study

ABSTRACT Background Surgical stress response initiates a complex pathophysiological cascade that alters fluid distribution and intravascular volume. In elective total hip arthroplasty (THA), the perioperative blood loss is potentially substantial, a significant part of the loss b …

21.07.2026

Management of Pain in the Intensive Care Unit: A Nordic Survey

ABSTRACT Background Pain is common in intensive care unit (ICU) patients with up to one‐third experiencing pain at rest and even more during mobilization and clinical procedures. This survey aimed to explore physicians' attitudes and preferences regarding pain management in adult …

17.07.2026

Catheter‐Based Therapies for Intermediate‐High Risk Pulmonary Embolism: A Protocol for a Systematic Review With Bayesian Pairwise and Network Meta‐Analyses

ABSTRACT Background Intermediate‐high risk pulmonary embolism ( PE ) represents a clinically challenging subgroup of acute PE , characterized by right ventricular dysfunction and increased risk of hemodynamic deterioration despite treatment with anticoagulation therapy. Although …

12.07.2026 · 1 Zitationen

Pediatric In‐Hospital Cardiac Arrest in Sweden: A Tertiary Care Cohort With High Survival

ABSTRACT Background Pediatric in‐hospital cardiac arrest is a rare event. Despite Sweden's extensive national health registries, data describing pediatric in‐hospital cardiac arrest are limited. In 2018, pediatric‐specific variables were introduced into the Swedish Registry for C …

09.07.2026

Patient‐Reported Outcome Measures After Labor Epidural Analgesia: Mental Presence as a Patient‐Centered Endpoint

07.07.2026

Prevalence and Risk Factors of Pressure Injuries in Norwegian Intensive Care Units: A Secondary Analysis

ABSTRACT Background Pressure injuries among critically ill patients are complications that may lead to increased morbidity, prolonged hospital stays, and higher healthcare costs. Despite this fact, there is limited national data on the prevalence of pressure injuries in Norwegian …

07.07.2026

Turnover Intentions Among Intensive Care Healthcare Workers: Key Factors Influencing Decisions to Stay or Leave

ABSTRACT Background Turnover among healthcare workers (HCWs) is highly prevalent in intensive care units (ICUs). Due to demanding workloads, stressful conditions, and increasing pressure to work more efficiently, this problem is likely to persist. Consequently, implementing proac …

06.07.2026

Reply to Gunka Et al.: Patient‐Reported Outcome Measures After Labor Epidural Analgesia: Mental Presence as a Patient‐Centered Endpoint

03.07.2026

Impact of Higher Versus Lower Blood Pressure Targets on Pulmonary Vascular Hemodynamics During Intensive Care After Out‐of‐Hospital Cardiac Arrest

ABSTRACT Background Hemodynamic management after out‐of‐hospital cardiac arrest (OHCA) is critical, yet the impact of vasopressor‐driven mean arterial pressure (MAP) targets on pulmonary circulation and right ventricular (RV) function remains unclear. Methods In this substudy of …

02.07.2026

Early Labour Epidural for Parturients With High BMI —A National Danish Survey

ABSTRACT Background Obesity in pregnancy increases obstetric and anaesthetic risk. Although early neuraxial access is frequently recommended for parturients with high BMI, the evidence base is limited, and national implementation has not been investigated. We aimed to describe cu …

30.06.2026

Contrast Media and Acute Kidney Injury in the ICU

ABSTRACT Background Acute kidney injury (AKI) is frequent and influences the prognosis of intensive care unit (ICU) patients. AKI may be categorised as contrast‐associated AKI (CA‐AKI). We investigated the development of CA‐AKI, including temporal and dose–response relationships. …

29.06.2026

The Impact of Diuretics on Mortality in Acute Kidney Injury With or Without Fluid Accumulation in Intensive Care—A Retrospective Cohort Study

ABSTRACT Background Acute kidney injury (AKI) is common in the intensive care unit (ICU) and associated with increased mortality. While diuretics are widely used to manage fluid accumulation, their impact on survival in established AKI remains uncertain. Methods This retrospectiv …

28.06.2026

Authors' Response to “Vasopressors in Early Burn Resuscitation: Physiological Concerns Revisited”

25.06.2026

Backrest Position and Outcome in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multi‐Center Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest ( DANOHCA ) Trial

ABSTRACT Background Intensive care following resuscitation from out‐of‐hospital cardiac arrest (OHCA) is based on a set of interventions, all of which are intended to reduce anoxic brain injury and improve outcomes, including sedation, mechanical ventilation, circulatory optimiza …

25.06.2026

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE ‐A Cohort of 1.2 Million Surgeries

ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models. Objectives To identify pr …

24.06.2026

Dexamethasone Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Study Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest Trial ( DANOHCA )

ABSTRACT Background The inflammatory response to whole‐body ischemia, as seen in comatose survivors after out‐of‐hospital cardiac arrest (OHCA), is associated with increased morbidity and mortality. Early high‐dose dexamethasone may dampen the inflammatory response, which may dim …

24.06.2026

Use of Prokinetic Agents in Adult ICU Patients: An International Inception Cohort Study ( PATIENCE )

ABSTRACT Background Feeding intolerance is common in intensive care unit (ICU) patients, but evidence supporting prokinetic use is limited. We aimed to provide international epidemiological data on the use of prokinetic agents in adult ICU patients and to explore potential associ …

23.06.2026

Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest ( DANOHCA ) Trial

ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic s …

23.06.2026

The Danish Out‐of‐Hospital Cardiac Arrest Trial: A Statistical Analysis Plan

ABSTRACT Background Post‐cardiac arrest care for patients resuscitated from out‐of‐hospital cardiac arrest (OHCA) includes multiple pharmacological and physiological interventions, yet optimal strategies to reduce post‐cardiac arrest syndrome–related morbidity and mortality remai …

23.06.2026

Issue Information

23.06.2026

Spinal Cord and Central Nervous System Distribution of Epidural Oxycodone—Experimental Pregnant Sheep Model

ABSTRACT Background Epidural oxycodone is a highly effective analgesic. However, oxycodone's distribution in the spinal cord after epidural injection is not known. In this experimental study, we evaluated the segmental spinal cord, brain, cerebrospinal fluid and plasma distributi …

21.06.2026

The Tale of the Two Circulations

19.06.2026

Glucagon‐Like Peptide‐1 Agonist vs. Placebo and Pulmonary Decline After Open‐Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial

ABSTRACT Background Postoperative pulmonary decline is an established complication of open‐heart surgery extending beyond the immediate postoperative phase. Inflammation‐mediated lung damage and ischaemia‐reperfusion injury secondary to extracorporeal circulation is a proposed pa …

16.06.2026

Remifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation—The ROCVIDEO Trial Protocol

ABSTRACT Background Routine use of neuromuscular blocking agents (NMBAs) is widely recommended to facilitate tracheal intubation. However, NMBA use is associated with potential adverse effects, including postoperative respiratory complications, intraoperative awareness and anaphy …

16.06.2026 · 1 Zitationen

Developing a Core Outcome Measurement Set for Adult ICU Patients, the CoreMS ‐ ICU —A Protocol

ABSTRACT Background Core outcome measurement sets (COMS) enhance the consistency and comparability of outcome reporting in clinical research. However, their effectiveness depends on the selection of valid, reliable, and feasible measurement instruments. Core outcome sets (COS) an …

16.06.2026

Establishing Expert Consensus on Competencies for Safe Ward‐Based Postoperative Epidural Analgesia Management: Protocol for a Modified Delphi Study

ABSTRACT Postoperative epidural analgesia (EA) is an important analgesic strategy for selected surgical procedures. However, clinical practice and training vary across settings, and no consensus‐based framework currently defines the competencies required for safe ward‐based EA ma …

16.06.2026

Subcutaneous Tranexamic Acid Achieves Comparable Serum Concentrations to Intramuscular Administration During Haemorrhagic Shock in a Swine Model

ABSTRACT Background Tranexamic acid is an antifibrinolytic agent reducing mortality when administered to trauma patients with haemorrhagic shock. This mortality reduction is time sensitive. Increased intramuscular dose administration has proven an effective alternative to intrave …

15.06.2026 · 1 Zitationen

General Anaesthesia Versus Spinal Anaesthesia for Outpatient Total Hip and Knee Arthroplasty: A Randomised Trial Protocol

ABSTRACT Introduction Same‐day discharge after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is increasing, but the optimal anaesthetic technique for outpatient pathways remains uncertain. Neuraxial anaesthesia is widely recommended based on observational …

15.06.2026

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events ( STEPCARE ‐ MAKE ): A Protocol for a Pre‐Planned Sub‐Study of a Randomized Clinical Trial

ABSTRACT Background Acute kidney injury (AKI) is a common and serious complication after cardiac arrest, affecting more than 30% of initially successfully resuscitated patients, with around 10% receiving Kidney Replacement Therapy (KRT). Currently, treatment options to prevent re …

14.06.2026

Association of Age, Sex and ASA Physical Status With Bispectral Index Values During General Anaesthesia: A Large Observational Cohort Study

ABSTRACT Background Depth of anaesthesia (DoA) is often guided by standard dosing protocols and evaluated through clinical signs, assuming these signs reliably indicate unconsciousness. However, this assumption is problematic: patients respond differently to anaesthetic drugs, an …

14.06.2026

COVID‐19 Mortality in Swedish Intensive Care Units: A Multicenter Survival Analysis

ABSTRACT Background Mortality among critically ill COVID‐19 patients has varied globally. In Sweden, geographic differences in mortality have also been observed. The current study aimed to determine whether mortality differences persist after adjusting for differences in case‐mix …

12.06.2026

Central Venous Pressure Referencing in the Lateral Position: Comparison With Direct Right Atrial Pressure in Mechanically Ventilated ICU Patients

ABSTRACT Background Right atrial pressure (RAP) is a key determinant of venous return and reflects right‐sided filling pressures in critically ill patients. Central venous pressure (CVP) is commonly used as a surrogate, but its accuracy depends on appropriate transducer levelling …

11.06.2026 · 1 Zitationen

Commentary: Vasopressors in Early Burn Resuscitation: Physiological Concerns Revisited

09.06.2026

Perioperative Antibiotic Prophylaxis in Burn Patients: Protocol for a Systematic Review

ABSTRACT Background Burn injuries are associated with substantial morbidity and mortality worldwide, with infections representing a major complication. The desirable and undesirable effects of perioperative antibiotic prophylaxis in burn patients are unresolved. Methods/Design We …

07.06.2026

Early Versus Late Wake‐Up Call After Out‐Of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest ( DANOHCA ) Trial

ABSTRACT Background Survivors of out‐of‐hospital cardiac arrest (OHCA) who remain comatose after return of spontaneous circulation are routinely sedated and mechanically ventilated during early post‐resuscitation care. Although prolonged sedation has traditionally been considered …

04.06.2026

Agreement Between Methods Assessing Changes in Plasma Volume During Fluid Therapy—A Post Hoc Analysis of a Randomized Trial

ABSTRACT Volume status of a patient is difficult to assess clinically. Methods to measure plasma volume as well as changes in plasma volume in connection with fluid therapy are therefore valuable for research purposes and could potentially be used bedside to guide fluid therapy i …

01.06.2026

Preferences for Blood Glucose Management in Adult Intensive Care Unit Patients—An International Survey

ABSTRACT Introduction Hyperglycaemia is common in intensive care unit (ICU) patients and blood glucose management practices likely vary, but there are limited contemporary data on ICU doctors' and nurses' preferences. Methods We conducted an international online survey of ICU doc …

31.05.2026

Prehospital Use of Non‐Invasive Ventilation for Acute Respiratory Failure due to Acute Exacerbation of Chronic Obstructive Pulmonary Disease. A Randomised Trial

ABSTRACT Background In‐hospital use of non‐invasive ventilation improves outcomes in patients with acute respiratory failure caused by acute exacerbation of chronic obstructive pulmonary disease. Prehospital use of non‐invasive ventilation is uncommon due to diagnostic uncertaint …

28.05.2026

Secondary Analysis of the CAN ‐Study, a Randomised Controlled Trial – Local Anaesthesia and Overall Survival

ABSTRACT Introduction This study investigates long‐term survival in the Cancer and Anaesthesia (CAN) study, focusing on the potential impact of local anaesthetic infiltration during breast cancer surgery. A positive effect from peritumoral infiltration has recently been suggested …

26.05.2026

Pantoprazole Use in Invasively Ventilated Patients With Septic Shock: A Protocol and Statistical Analysis Plan

ABSTRACT Sepsis is a recognized risk factor for upper gastrointestinal bleeding, yet sepsis‐specific randomized evidence informing stress ulcer prophylaxis remains limited. This protocol describes the rationale, methods, and statistical analysis plan for a post hoc subgroup analy …

22.05.2026 · 1 Zitationen

Digital Versus in‐Person Pre‐Anaesthetic Assessment and Postoperative Outcomes in Low‐Risk Patients: A Protocol for a Single‐Centre Cohort Study

ABSTRACT Pre‐anaesthetic assessment is essential for identifying perioperative risk and optimising patient safety. Digital alternatives, including video consultation and structured electronic health record (EHR) review, may improve efficiency, but comparative evidence regarding p …

22.05.2026

Glucocorticoids for Patients With Acute Decompensated Heart Failure: A Protocol for a Systematic Review With Meta‐Analysis and Trial Sequential Analysis

ABSTRACT Background Acute decompensated heart failure (ADHF) is associated with inflammation. Inflammatory biomarkers in patients with ADHF are associated with increased mortality. Glucocorticoids mitigate systemic inflammation and may therefore have a therapeutic role in ADHF. W …

19.05.2026

ICU Clinicians' View on Platelet Transfusion Thresholds for a Future Trial—Protocol for an International Survey

ABSTRACT Background Thrombocytopenia is frequent in adult intensive care unit (ICU) patients and may contribute to adverse outcomes, including bleeding, morbidity and mortality. To reduce the risk of bleeding, platelet transfusions are commonly used, yet transfusion thresholds va …

15.05.2026

Swedish Intensive Care Physicians' Attitudes Towards Withholding or Withdrawing Life‐Sustaining Treatment in Critically Ill Children

ABSTRACT Background Decisions to withhold or withdraw life‐sustaining treatments for critically ill children are challenging. This study aims to identify Swedish intensivists' attitudes, values and experiences towards the decision‐making process concerning withholding or withdraw …

14.05.2026

Association of Suspected Aspiration During of Out‐Of‐Hospital Cardiac Arrest With Development of Early‐Onset Pneumonia

ABSTRACT Background Early‐onset pneumonia is a possible complication after out‐of‐hospital cardiac arrest (OHCA) resuscitation. Whether or not a suspected aspiration during prehospital care is associated with the development of early‐onset pneumonia has not been studied. Methods …

13.05.2026

Malignant Hyperthermia in Sweden: Clinical Presentations and Genetic Findings

ABSTRACT Introduction Malignant hyperthermia (MH) is a pharmacogenetic, hypermetabolic and potentially lethal reaction to potent volatile anaesthetics and the muscle relaxant succinylcholine. To improve the understanding of MH, the aim of this retrospective study was to describe …

13.05.2026 · 1 Zitationen

A Systematic Review and Expert Evaluation of Perioperative SGLT2 Inhibitor‐Associated Ketoacidosis Case Reports

ABSTRACT Introduction The use of sodium–glucose cotransporter‐2 inhibitors (SGLT2i) in the perioperative setting may lead to SGLT2i‐associated postoperative ketoacidosis (SAPKA) in patients with type 2 diabetes (T2D). Therefore, cessation of this drug is recommended before surger …

13.05.2026

Ultrasound‐Guided Superficial Parasternal Intercostal Plane Block for Early Pain Management in Patients Undergoing Cardiac Surgery—A Randomized Controlled Trial

ABSTRACT Background Sternotomy causes substantial postoperative pain. Recently, several less invasive nerve blocks have been described that are safer to use even on anticoagulated patients. This study aims to evaluate early pain management using ultrasound‐guided superficial para …

13.05.2026

Whole Blood Transcriptomic Response to Perioperative Dexamethasone in Total Knee Arthroplasty: A Targeted Panel Analysis

ABSTRACT Background Changes in the transcriptome of immune cells are predictive of clinical outcomes. These effects may be surgery‐specific and possibly modulated by glucocorticoids. We investigated the immune response and the impact of dexamethasone on the response in patients u …

13.05.2026

Pre‐ and Postoperative N‐Terminal Pro B‐Type Natriuretic Peptide Dynamics and Outcomes After Emergency Laparotomy

ABSTRACT Background The prognostic value of N‐terminal pro B‐type natriuretic peptide has only been sparsely studied in patients undergoing emergency laparotomy, where acute systemic inflammation and physiological derangement may affect perioperative N‐terminal pro B‐type natriur …

12.05.2026

Mapping the Clinical Evidence on Remimazolam in Anaesthesia: A Protocol for a Scoping Review

ABSTRACT Background Remimazolam is a recently introduced benzodiazepine used for procedural sedation and general anaesthesia. Its pharmacokinetic profile, including rapid metabolism and predictable recovery, has generated interest in its potential advantages compared with traditi …

09.05.2026

Effect of Ultrasound‐Guided Lateral Infraclavicular Brachial Plexus Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures: A Randomized Controlled Noninferiority Trial

ABSTRACT Background Closed reduction of distal radius fractures is painful, and current analgesic strategies may be inadequate. Ultrasound‐guided lateral infraclavicular brachial plexus block may offer complete analgesia and muscle relaxation, potentially improving patient comfor …

07.05.2026

Cognitive Functioning After Circulatory Shock: A Prospective Observational Study

ABSTRACT Background Cognitive impairment in intensive care unit (ICU) survivors is multifactorial and can affect especially memory, attention, and executive functions. This study aimed to determine the cognitive functioning of patients with circulatory shock immediately after ICU …

06.05.2026

Combined Transversus Abdominis Plane and Rectus Sheath Blocks in Open Inguinal Hernia Repair: Protocol for a Double‐Blind Randomized Controlled Trial ( PRO ‐ RSTAP )

ABSTRACT Background Inguinal hernia repair is one of the most common surgical procedures worldwide and is frequently performed as day‐case surgery. Postoperative pain may delay recovery and occasionally necessitate unplanned hospital admission. Regional anesthesia techniques, inc …

05.05.2026

Does Speaking the Same Language With the Caretakers Associate With a Higher Neuraxial Labor Analgesia Use Rate?

ABSTRACT Use of neuraxial analgesia requires communication between the parturient and her caretakers. In this retrospective study, the use of labor analgesia is compared between parturients whose primary language is other than Finnish or Swedish and who don't communicate in these …

05.05.2026

An Observational Study of Changes in Renin Concentrations and Associations With Complications Following Cardiac Surgery

ABSTRACT Background Increased plasma renin concentrations have been reported in patients following cardiac surgery while correlations to clinical outcomes have varied. More evidence is needed to support the potential clinical utility of plasma renin as a biomarker guiding postope …

04.05.2026

Anesthetic Management for Manual Removal of Retained Placenta in Parturients Without Labor Epidural Analgesia: A Retrospective Multicenter Real‐World Study

ABSTRACT Background Manual removal of placenta (MRP) is required in 0.1%–3.3% of vaginal births. For patients who give birth without labor epidural analgesia, the choice between neuraxial or general anesthesia (GA) with or without tracheal intubation presents unique challenges. T …

30.04.2026

Initiation of High‐Potency Benzodiazepine Prescriptions Among Survivors of Severe Trauma

ABSTRACT Background Trauma is a major public health concern that often leads to long‐term psychological distress and chronic pain. Benzodiazepines (BZDs) are sometimes prescribed for anxiety, insomnia, or acute stress‐related symptoms, but long‐term use is associated with depende …

26.04.2026

Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single‐Center Cohort Study

ABSTRACT Background Air pollution, especially particle pollution, is increasingly recognized as a potential perioperative risk factor, yet modeling environmental exposures in surgical cohorts remains methodologically underdeveloped. We demonstrate a Bayesian hierarchical framewor …

26.04.2026

A Wireless Photoplethysmography Chest Patch for Continuous Vital Sign Monitoring: A Clinical Validation Study in Intensive Care Patients

ABSTRACT Background Continuous vital sign monitoring with wearable biosensors enables earlier detection of clinical deterioration and improves patient safety. This study validated an integrated wireless photoplethysmography‐based chest patch biosensor (Biobeat technology Ltd) cap …

24.04.2026

Cognitive Rehabilitation Interventions in the Intensive Care Unit: A Systematic Integrative Review

ABSTRACT Background Because critical illness, sedation, and ICU treatment commonly disrupt attention, memory, and executive function, early cognitive rehabilitation during the ICU stay may preserve or restore these capacities, reduce the delirium burden, and support engagement an …

22.04.2026

Issue Information

22.04.2026 · 1 Zitationen

A Possible Explanation to the Enigmatic Difference Between Ventilatory and Reversed Fick Assessments of Whole‐Body VO 2

17.04.2026 · 2 Zitationen

Early Prediction of Neurological Outcome After Cardiac Arrest‐Rationale and Design of the Prospective International Observational EARLY ‐ NEURO , a STEPCARE Substudy

ABSTRACT Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and those with no or minimal brain injury may be identified b …

16.04.2026

Risks of Serious Adverse Events Associated With Non‐Steroidal Anti‐Inflammatory Drugs in Orthopaedic Surgery. A Systematic Review With Meta‐Analysis and Trial Sequential Analysis

ABSTRACT Background Non‐steroidal anti‐inflammatory drugs (NSAIDs) are recommended for perioperative analgesic treatment. However, NSAID treatment may be associated with increased risk of adverse events. We investigated the risks of serious adverse events with perioperative NSAID …

14.04.2026

Diagnostic Accuracy of Arm Conicity to Detect Inaccurate Non‐Invasive Blood Pressure Measurement in Obese Patients

ABSTRACT Non‐invasive blood pressure (NIBP) measurement can be challenging in patients with obesity. We aimed to determine if arm conicity, mid arm circumference or body mass index (BMI) could be used to predict pre‐operative and intra‐operative NIBP measurement error. Eligible p …

09.04.2026

Hematologic Malignancies in Critical Care: A National Observational Comparison Between ICU and Non‐ICU Patients

ABSTRACT Purpose Critically ill patients with hematologic malignant (HM) diseases are a heterogeneous but vulnerable group, where intensive care (ICU) is associated with high mortality. The impact of ICU care on long‐term survival is less well described. This retrospective nation …

08.04.2026

Drainage of Pleural Effusion in the Intensive Care Unit ( DOPE ‐ ICU ) Feasibility Trial—Protocol and Statistical Analysis Plan

ABSTRACT Pleural effusions are common in adult intensive care unit (ICU) patients with respiratory failure. Ultrasonography‐guided therapeutic pleural drainage is widely used and associated with improved oxygenation and ventilatory parameters, but no randomised clinical trial dat …

02.04.2026

The Influence of Profession, Experience and Geographical Region on Intra‐ and Postoperative Opioid Practice in Denmark: A Post Hoc Analysis of the OPIAID Survey

ABSTRACT Background Clinicians often administer opioids to manage postoperative pain, but with considerable variation in chosen opioid and dosing strategies. This post hoc analysis of a Danish nationwide survey assessed how profession, length of experience, and geographical regio …

02.04.2026

Effects of Peri‐Operative Glucocorticoids in Hip Fracture Patients on Post‐Operative Outcomes: Systematic Review Protocol

ABSTRACT Background Hip fracture patients are often elderly and frail, with a high burden of comorbidity, placing them at substantial risk of post‐operative delirium and other complications. Post‐operative delirium is associated with prolonged recovery, functional decline, increa …

30.03.2026

Adverse Effects Associated With Spinal Versus General Anaesthesia for Hip and Knee Arthroplasties: Protocol for a Systematic Review

ABSTRACT Background Spinal and general anaesthesia are the most common anaesthetic methods for hip and knee arthroplasties. Differences in their effects on short‐ and long‐term postoperative outcomes, including mortality morbidity, and adverse events, remain uncertain. Identifyin …

30.03.2026 · 3 Zitationen

Effects of Continuous Versus Intermittent Glucose Monitoring in Intensive Care Unit Patients: A Systematic Review With Meta‐Analysis

ABSTRACT Introduction Glucose management in intensive care unit (ICU) patients often relies on point of care (POC) blood glucose measurements. An increasing number of randomized clinical trials (RCTs) have investigated continuous glucose monitoring (CGM) compared to POC, but effe …

26.03.2026

Issue Information

26.03.2026

Severity of Illness and Mortality According to Time of Admission to Intensive Care

ABSTRACT Introduction Staffing at hospital wards is at its lowest during nighttime, which may endanger prompt recognition of the need for intensive care. High severity of illness of patients admitted to the intensive care unit (ICU) in the morning may reflect delayed referral for …

26.03.2026

Key Features of Contemporary Pilot and Feasibility Trials: Protocol for a Methodological Study

ABSTRACT Background Randomised clinical trials (RCTs) are costly undertakings requiring careful design, planning and conduct. Failure to achieve timely participant recruitment, separation between intervention groups and adequate follow‐up contributes to waste in research. Pilot R …

21.03.2026

Mortality Predictions Including Pre‐Admission Functional Status in ICU Patients With Delirium—A Substudy of the AID ‐ ICU Trial

ABSTRACT Purpose Pre‐admission functional status affects patients' ability to overcome the deteriorating effects of acute critical illness. We aimed to develop a clinical prediction model for 90‐day and 1‐year mortality based on pre‐admission data, including functional status, in …

19.03.2026

Activities and Time Spent on Rehabilitation in Scandinavian ICUs : A Cross‐Sectional Survey Among Healthcare Professionals

ABSTRACT Introduction Survivors of critical illness commonly experience physical, cognitive, and psychological impairments. Early rehabilitation may mitigate these impairments; however, how rehabilitation practices are perceived and implemented by healthcare professionals in inte …

16.03.2026 · 1 Zitationen

Advanced Hemodynamic Monitoring During Postresuscitation Care After Out‐of‐Hospital Cardiac Arrest: Protocol for a Scoping Review

ABSTRACT Introduction Out‐of‐hospital cardiac arrest (OHCA) is associated with high mortality and substantial long‐term neurological sequelae among survivors. During postresuscitation intensive care after return of spontaneous circulation (ROSC), myocardial dysfunction, vasoplegi …

16.03.2026

Response to: “Impact of Rehabilitation in the Neurointensive Care Unit on Long‐Term Survival in Patients With Traumatic Brain Injury”

16.03.2026

Occurrence of Hypoxemia the First Day After Trauma Assessed by Continuous Pulse Oximetry

ABSTRACT Background Trauma is a leading cause of death and disability in young adults. Although supplemental oxygen is recommended early after trauma to prevent hypoxemia, evidence regarding the occurrence and distribution of hypoxemic episodes, to raise awareness on potential cl …

14.03.2026 · 1 Zitationen

The Relationship Between the American Society of Anesthesiologists Physical Status Classification and Patient Outcomes: A Scoping Review Protocol

ABSTRACT Background The American Society of Anesthesiologists Physical Status (ASA‐PS) classification system is ubiquitous in perioperative medicine and research as a tool for preoperative patient risk stratification. Despite widespread clinical adoption as a predictor of periope …

13.03.2026 · 1 Zitationen

Neuromuscular Block and Video Laryngoscope to Facilitate Intubation—A Survey of Current Practice in Denmark and Sweden

ABSTRACT Background Neuromuscular blocking agents (NMBA) provide optimal conditions for tracheal intubation. A high dose of opioid can be used as an alternative but may give suboptimal conditions for intubation. The use of a video laryngoscope for intubation might eliminate this …

12.03.2026

Continuous Glucose Monitoring With Real‐Time Alerts to Achieve Glycaemic Control in Surgical Patients With Diabetes: Protocol for a Multicentre, Randomised, Clinical Trial

ABSTRACT Background Perioperative glucose monitoring traditionally relies on intermittent point‐of‐care (POC) testing, whereas continuous glucose monitoring (CGM) enables real‐time glucose assessment with automated alerts for dysglycaemia. CGM remains understudied in hospitalised …

12.03.2026

Renal Adverse Events Associated With Ibuprofen Treatment After Hip and Knee Arthroplasties— A Protocol for the Preplanned Substudy of the PERISAFE Trial

ABSTRACT Introduction Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used for postoperative pain management after hip and knee arthroplasties but have been associated with renal adverse effects. The risk may increase when NSAIDs are combined with diuretics and angiot …

11.03.2026 · 1 Zitationen

Anatomical Coordinates for Adductor Canal Block: Targeting Saphenous Nerve and Nerve to Vastus Medialis

ABSTRACT Background The adductor canal block effectively targets the saphenous nerve and nerve to vastus medialis, providing pain relief after total knee arthroplasty while preserving quadriceps strength. Despite its widespread use, the ideal needle insertion point remains uncert …

10.03.2026 · 1 Zitationen

Bicarbonate and Other Buffer Therapies in Acute Metabolic Acidosis: A Systematic Review and Meta‐Analysis

ABSTRACT Background The aim of this study was to perform a systematic review and meta‐analysis on the effect of buffering therapies on clinical outcomes in adult patients with acute metabolic acidosis. Methods Searches were conducted in Embase, Cochrane, and PubMed for randomised …

08.03.2026

Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients—A Retrospective Study

ABSTRACT Background The reported prevalence of pulmonary embolism (PE) detected during intensive care varies substantially. Computed tomography pulmonary angiography (CTPA) is the diagnostic reference method, but assessing pre‐test probability and finding distinct indications for …

27.02.2026

APECx —Anaesthesia, Perfusion and Surgical Practices in Cardiac Surgery: Main Study Protocol of a Modular Multiphase Prospective International Multicentre Observational Study

ABSTRACT The perioperative management in adult cardiac surgery patients remains highly variable across centres and regions. The APECx study (Anaesthesia, Perfusion and surgical practicEs in Cardiac surgery) aims to describe the incidence of key clinical patient outcomes, map glob …

26.02.2026

National Online Peer Support for People Recovering From Critical Illness and Their Families: A Study Protocol

ABSTRACT Background People surviving critical illness often experience long‐lasting impairments of varying severity known as post‐intensive care syndrome. These challenges persist well beyond hospital discharge and affect not only patients but also their families. Peer support se …

26.02.2026 · 1 Zitationen

Testing of Pre‐Operative Peripheral Nerve Blocks in Randomised Controlled Trials: A Scoping Review

ABSTRACT Background Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgery, but the methods used to assess their success vary substantially. This scoping review examined contemporary research practises and the extent to which trials report on peri …

25.02.2026

Why Am I Getting Less Detached? Reflections on End‐Of‐Life Care

25.02.2026 · 1 Zitationen

Predictors of Acute Postoperative Pain in Cancer Patients Undergoing Elective Video‐Assisted Thoracoscopic Surgery

ABSTRACT Introduction Postoperative pain after video‐assisted thoracoscopic surgery affects 43%–99% of patients and is associated with prolonged hospital stay. Pre‐ and intraoperative risk factors can help identify patients at higher risk of postoperative pain. This study aimed t …

25.02.2026

Issue Information

25.02.2026

Translation and Cultural Adaption of the Revised ICU Family Satisfaction Questionnaire ( FS ‐ ICU ‐ 24R ) Into Danish

ABSTRACT Background Systematic assessment of family satisfaction is essential for improving the quality of care in intensive care units (ICUs). The Family Satisfaction with Care in the Intensive Care Unit questionnaire (FS‐ICU‐24R) is internationally used but has not previously b …

22.02.2026

Treatment‐Limiting Decisions in Neurointensive Care: Withholding or Withdrawal of Life‐Sustaining Measures

ABSTRACT Background Treatment‐limiting decisions (TLDs) in neurointensive care are frequently reported with no distinction between withholding and withdrawal of treatment. We investigated the proportion of patients subjected to withholding and withdrawal of life‐sustaining treatm …

19.02.2026

Rehabilitation After Moderate‐To‐Severe Traumatic Injury: A Protocol for a Scoping Review

ABSTRACT Background Traumatic injury is a leading cause of death and disability worldwide. Advances in acute trauma care have improved survival rates, shifting the focus towards long‐term outcomes and the role of rehabilitation in recovery. Although rehabilitation is clearly defi …

19.02.2026 · 2 Zitationen

Glucose Management in the ICU : The Bi‐Centre GEM ‐ ICU Cohort Study

ABSTRACT Introduction Dysglycaemia is common in intensive care unit (ICU) patients and has been associated with worse outcomes. Data on glucose management and insulin use from contemporary intensive care units (ICUs) are limited. Methods We conducted a bi‐centre, retrospective co …

16.02.2026 · 1 Zitationen

Evaluating Shivering and Hypothermia After Removing Forced‐Air Heating From Short‐Duration Surgery

ABSTRACT Background Single‐use forced‐air heating blankets can prevent intraoperative hypothermia, but their use carries environmental and economic costs. Whether omitting heating blankets for short‐duration surgical procedures affects patient outcomes remains unclear. Objectives …

16.02.2026

Albumin for Adult ICU Patients With Shock: Protocol for the INCEPT ‐Albumin Platform Trial Domain

ABSTRACT Background Intravenous albumin is used for resuscitation of adult intensive care unit (ICU) patients with shock and substitution in those with hypoalbuminemia, which is common in critically ill patients. There is, however, substantial clinical practice variation as it is …

15.02.2026 · 1 Zitationen

Automated Calculation of Sequential Organ Failure Assessment ( SOFA ) Score in the Intensive Care Unit: Algorithm Development, Validation, and Association With 30‐Day Mortality

ABSTRACT Background Sequential Organ Failure Assessment (SOFA) score is routinely used in the intensive care unit (ICU) to describe severity of organ dysfunction, for prognostication and sepsis diagnosis, and in clinical trials. Inter‐rater variability and scalability are known c …

12.02.2026

Anesthesia Practices for Preterm Infants: A Survey in the Nordic Countries and Review of the Literature

ABSTRACT Background Preterm infants are at increased risk of perioperative mortality and are among the most vulnerable patients anesthesiologists can encounter. The literature on anesthesia practice in preterm infants is limited, mainly focusing on their physiological immaturity …

08.02.2026 · 2 Zitationen

Recommendations for Stress Ulcer Prophylaxis in Critically Ill Adults: A Contextualized Clinical Practice Guideline From the Saudi Critical Care Society and the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Endorsed by the Kuwait Anesthesia and Critical Care Society

ABSTRACT Background Critically ill adults are at risk for stress‐related upper gastrointestinal bleeding (UGIB). Regional variations in gastrointestinal bleeding incidence, infection epidemiology, formulary access, and the relative value placed on bleeding versus infection outcom …

05.02.2026 · 1 Zitationen

The Impact of Early Postoperative Oral Intake on the Length of Hospital Stay: A Meta‐Analysis

ABSTRACT Background International guidelines regarding the resumption of postoperative intake of liquids are limited. Surgical patients are subjected to unnecessarily prolonged fasting times after surgery, which can lead to increased postoperative complications. Research has show …

03.02.2026 · 2 Zitationen

Intraoperative Hypotension and Vasoactive Treatment: An International Survey of Anaesthesiologists

ABSTRACT Background Intraoperative hypotension is a common occurrence in patients undergoing anaesthesia, although there is no standardised definition of hypotension. International consensus statements provide some guidelines for the management of intraoperative hypotension, but …

02.02.2026 · 1 Zitationen

The Association Between Endothelial Biomarkers and Intravascular Albumin Loss After Major Abdominal Surgery—An Exploratory Pilot Study

ABSTRACT Background Elevated endothelial biomarkers may indicate damage to the endothelium and increased fluid loss after surgery. This study aimed to assess endothelial damage after pancreatic surgery with selected biomarkers and transvascular fluid loss assessed with radioactiv …

30.01.2026

Low‐Molecular‐Weight Heparin for Adult ICU Patients Who Require Thromboprophylaxis: Protocol for the INCEPT ‐Thromboprophylaxis Platform Trial Domain

ABSTRACT Background Low‐molecular‐weight heparin (LMWH) is recommended for thromboprophylaxis in adult intensive care unit (ICU) patients. Despite its widespread use, there is insufficient evidence on the optimal dose, and there appears to be practice variation. Determining the L …

28.01.2026

Correction to “Failure to Protect Against Myocardial Ischemia‐Reperfusion Injury With Sevoflurane Postcondioning in Old Rats In Vivo”

28.01.2026 · 3 Zitationen

Parturients' Perspectives on Labor Pain and Epidural Analgesia: An Explorative Qualitative Study

ABSTRACT Background Labor pain is among the most intense forms of pain, yet its subjective and multidimensional nature makes it challenging to assess and manage. Labor epidural analgesia is the most effective method of relief, but clinical practice often emphasizes physical outco …

28.01.2026

Correction to “Higher Versus Lower Mean Arterial Blood Pressure After Cardiac Arrest and Resuscitation ( MAP ‐ CARE ): A Protocol for a Randomized Clinical Trial”

28.01.2026 · 3 Zitationen

Vasopressor Use in Acute Burn Resuscitation: A Retrospective Study

ABSTRACT Background Vasopressors are often introduced in severe burn patients who respond poorly to fluid resuscitation to maintain adequate blood pressure and avoid fluid creep . This study aims to characterise these patients and explore potential correlations between vasopresso …

25.01.2026

Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians

ABSTRACT Background Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack …

25.01.2026 · 2 Zitationen

Anesthetic Strategies for Closed Reduction of Dislocated Total Hip Arthroplasty: A Scoping Review

ABSTRACT Background Total hip arthroplasty (THA) is a frequently performed orthopedic procedure, with dislocation being a common complication, often requiring closed reduction. Anesthetic strategies for this vary, and evidence on the efficacy, safety, and cost‐effectiveness of cu …

23.01.2026

Issue Information

23.01.2026

Informed Consent in Randomized Emergency Clinical Trials in Denmark: A Systematic Review and National Survey Protocol

ABSTRACT Background Informed consent is a fundamental part of clinical research involving human participants. However, in certain emergency medical situations, participants are unable to provide prospective informed consent before inclusion, or the urgency of the situation deems …

23.01.2026 · 2 Zitationen

Ultrasound Use in Anesthesiology and Intensive Care in the Nordic Countries—An International Survey on Availability, Frequency of Use, Operator Training, and Assessment

ABSTRACT Ultrasound is increasingly used in anesthesia and intensive care medicine for procedural guidance and patient assessment. However, training and formal skills assessment vary, and there is limited knowledge about current ultrasound practices in the Nordic countries. This …

19.01.2026

Correction to “Estimation of the Maximum Potential Cost Saving from Reducing Serious Adverse Events in Hospitalized Patients”

15.01.2026

Response: AKI During Cardiac Surgery—Still to Be Solved

14.01.2026

Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study

ABSTRACT Background Intraoperative hypotension is a well‐known clinical condition and often treated with vasoactive agents. Previous cohort studies have indicated that large numbers of patients receive this treatment, but they have been limited to specific surgical populations or …

13.01.2026 · 1 Zitationen

Dexmedetomidine for Emergence Delirium and Agitation in Preschool Children Undergoing Adeno‐Tonsillectomy: A Scoping Review Protocol

ABSTRACT Emergence delirium (ED) and emergence agitation (EA) are behavioural disturbances in the early postoperative period in children. Preschool‐aged children (1–6 years) undergoing adeno‐tonsillectomy constitute a high‐risk group. The α 2 ‐adrenergic agonist dexmedetomidine h …

13.01.2026

Association Between Severe Anaemia and Outcome in Moderate and Severe Traumatic Brain Injury: A Retrospective Cohort Study

ABSTRACT Background Anaemia is common among patients with traumatic brain injury (TBI), and it might contribute to the development of secondary brain injury. However, the impact of anaemia on outcome among TBI patients remains controversial. The aim of this study was to investiga …

09.01.2026 · 2 Zitationen

Impact of a Care Pathway for Older Patients Undergoing Emergency Abdominal Surgery: A Before‐and‐After Study

ABSTRACT Background Older patients undergoing emergency abdominal surgery face high risks of mortality and complications. Objective Investigate whether a care pathway designed for older patients improves surgical outcomes. Methods This single‐centre study investigated the effect …

06.01.2026 · 1 Zitationen

“End‐of‐Life Care Is as Important as Any Other Lifesaving Task”: A Scandinavian Survey Study

ABSTRACT Background Intensive care physicians often provide end‐of‐life (EOL) care in the intensive care units (ICUs). However, knowledge about the physicians' role and confidence in EOL care after the decision to withdraw life‐sustaining therapy is unknown. This study aimed to e …

06.01.2026

Issue Information

06.01.2026 · 1 Zitationen

Pre‐Anaesthesia Assessments of Adults Undergoing Elective Surgery: A Scoping Review

ABSTRACT Introduction Pre‐anaesthesia (PA) assessments aim to ensure that anaesthesia is administered as safely and efficiently as possible, minimising risks and improving patient care. While the goal remains the same, the content, delivery, setup and evaluation of PA assessments …