Vollständiger Abstract
Worum geht es in dieser Arbeit?
Abstract The global emergence and dissemination of epidemic Clostridioides difficile ribotype 027 (RT027) and related lineages illustrate the role of antimicrobial pressure in shaping the epidemiology of this pathogen. We propose a hierarchical model in which fluoroquinolones (FQs) served as the dominant selective force underlying the worldwide expansion of RT027-related strains, with rifampin and rifamycins acting as secondary modifiers that promoted persistence and regional dominance.
Bibliografischer Nachweis
Publikationsdaten
- Autor:innen
- Isabella A Tickler, Richard V Goering, Fred C Tenover
- Quelle
- Journal of Antimicrobial Chemotherapy
- Publikation
- 2026-09-04
- Band / Ausgabe
- 81 / 10
- Seiten
- Nicht angegeben
- ISSN / ISBN
- 0305-7453, 1460-2091
- Zitationen
- 0 laut Crossref
- Referenzen
- 24 hinterlegt
Zitieren
Zitierfähiger Nachweis
Isabella A Tickler, Richard V Goering, Fred C Tenover (2026). The underappreciated role of rifampin in shaping the epidemiology of RT027-like Clostridioides difficile lineages. Journal of Antimicrobial Chemotherapy, 81 (10). https://doi.org/10.1093/jac/dkag310
Kontext
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